References
- Szyf M . The early-life social environment and DNA methylation . Clin. Genet.81 ( 4 ), 341 – 349 ( 2012 ).
- Feinberg A . DNA methylation in cancer: three decades of discovery . Genome Med.6 ( 5 ), 36 ( 2014 ).
- Waalwijk C , FlavellRA . DNA methylation at a CCGG sequence in the large intron of the rabbit beta-globin gene: tissue-specific variations . Nucleic Acids Res.5 ( 12 ), 4631 – 4634 ( 1978 ).
- Razin A , SzyfM . DNA methylation patterns. Formation and function . Biochim. Biophys. Acta782 ( 4 ), 331 – 342 ( 1984 ).
- Kitamura E , IgarashiJ , MorohashiAet al. Analysis of tissue-specific differentially methylated regions (TDMs) in humans . Genomics89 ( 3 ), 326 – 337 ( 2007 ).
- Lister R , PelizzolaM , DowenRHet al. Human DNA methylomes at base resolution show widespread epigenomic differences . Nature462 ( 7271 ), 315 – 322 ( 2009 ).
- http://encodeproject.org/ENCODE/ .
- Tylee DS , KawaguchiDM , GlattSJ . On the outside, looking in: a review and evaluation of the comparability of blood and brain “-omes” . Am. J. Med. Genet. B Neuropsychiatr. Genet.162B ( 7 ), 595 – 603 ( 2013 ).
- Provençal N , SudermanMJ , GuilleminCet al. The Signature of maternal rearing in the methylome in rhesus macaque prefrontal cortex and T cells . J. Neurosci.32 ( 44 ), 15626 – 15642 ( 2012 ).
- Uddin M , AielloAE , WildmanDEet al. Epigenetic and immune function profiles associated with posttraumatic stress disorder . Proc. Natl Acad. Sci. USA107 ( 20 ), 9470 – 9475 ( 2010 ).
- Borghol N , SudermanM , McardleWet al. Associations with early-life socio-economic position in adult DNA methylation . Int. J. Epidemiol.41 ( 1 ), 62 – 74 ( 2012 ).
- Mehta D , KlengelT , ConneelyKNet al. Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder . Proc. Natl Acad. Sci. USA110 ( 20 ), 8302 – 8307 ( 2013 ).
- Weaver IC , CervoniN , ChampagneFAet al. Epigenetic programming by maternal behavior . Nat. Neurosci.7 ( 8 ), 847 – 854 ( 2004 ).
- Mcgowan PO , SasakiA , D’alessioACet al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse . Nat. Neurosci.12 ( 3 ), 342 – 348 ( 2009 ).
- Perroud N , Paoloni-GiacobinoA , PradaPet al. Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of trauma . Transl. Psychiatry1 , e59 ( 2011 ).
- Oberlander TF , WeinbergJ , PapsdorfM , GrunauR , MisriS , DevlinAM . Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses . Epigenetics3 ( 2 ), 97 – 106 ( 2008 ).
- Klengel T , MehtaD , AnackerCet al. Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions . Nat. Neurosci.16 ( 1 ), 33 – 41 ( 2013 ).
- Guintivano J , BrownT , NewcomerAet al. Identification and replication of a combined epigenetic and genetic biomarker predicting suicide and suicidal behaviors . Am. J. Psychiatry doi:10.1176/appi.ajp.2014.14010008. ( 2014 ) ( Epub ahead of print ).
- Unternaehrer E , LuersP , MillJet al. Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF) after acute psychosocial stress . Transl. Psychiatry2 , e150 ( 2012 ).
- Jack A , ConnellyJJ , MorrisJP . DNA methylation of the oxytocin receptor gene predicts neural response to ambiguous social stimuli . Front. Hum. Neurosci.6 , 280 ( 2012 ).
- Kim JM , StewartR , KangHJet al. A longitudinal study of BDNF promoter methylation and genotype with poststroke depression . J. Affect. Disord.149 ( 1–3 ), 93 – 99 ( 2013 ).
- Koenen KC , UddinM , ChangSCet al. SLC6A4 methylation modifies the effect of the number of traumatic events on risk for posttraumatic stress disorder . Depress. Anxiety28 ( 8 ), 639 – 647 ( 2011 ).
- Wang D , SzyfM , BenkelfatCet al. Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression . PLoS ONE7 ( 6 ), e39501 ( 2012 ).
- Nikolova YS , KoenenKC , GaleaSet al. Beyond genotype: serotonin transporter epigenetic modification predicts human brain function . Nat. Neurosci. doi:https://doi.org/10.1038/nn.3778 ( 2014 ) ( Epub ahead of print ).