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Research Highlights

Epigenetic reprogramming and blood development

Pages 9-11 | Published online: 17 Feb 2015

References

  • de Lima M , McNieceI , RobinsonSNet al. Cord-blood engraftment with ex vivo mesenchymal-cell coculture . N. Engl. J. Med.367 ( 24 ), 2305 – 2315 ( 2012 ).
  • Dahlberg A , DelaneyC , BernsteinID . Ex vivo expansion of human hematopoietic stem and progenitor cells . Blood117 ( 23 ), 6083 – 6090 ( 2011 ).
  • Chaurasia P , GajzerDC , SchanielC , D’SouzaS , HoffmanR . Epigenetic reprogramming induces the expansion of cord blood stem cells . J. Clin. Invest.124 ( 6 ), 2378 – 2395 ( 2014 ).
  • Milhem M , MahmudN , LavelleDet al. Modification of hematopoietic stem cell fate by 5aza 2’deoxycytidine and trichostatin A . Blood103 ( 11 ), 4102 – 4110 ( 2004 ).
  • Araki H , MahmudN , MilhemMet al. Expansion of human umbilical cord blood SCID-repopulating cells using chromatin-modifying agents . Exp. Hematol.34 ( 2 ), 140 – 149 ( 2006 ).
  • Araki H , YoshinagaK , BoccuniP , ZhaoY , HoffmanR , MahmudN . Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential . Blood109 ( 8 ), 3570 – 3578 ( 2007 ).
  • Chaurasia P , BerenzonD , HoffmanR . Chromatin-modifying agents promote the ex vivo production of functional human erythroid progenitor cells . Blood117 ( 17 ), 4632 – 4641 ( 2011 ).
  • Lioznov MV , FreibergerP , KrögerN , ZanderAR , FehseB . Aldehyde dehydrogenase activity as a marker for the quality of hematopoietic stem cell transplants . Bone Marrow Transplant.35 ( 9 ), 909 – 914 ( 2005 ).
  • Di Ruscio A , EbralidzeAK , BenoukrafTet al. DNMT1-interacting RNAs block gene-specific DNA methylation . Nature503 ( 7476 ), 371 – 376 ( 2013 ).
  • Khulan B , ThompsonRF , YeKet al. Comparative isoschizomer profiling of cytosine methylation: the HELP assay . Genome Res.16 ( 8 ), 1046 – 1055 ( 2006 ).
  • Bartholdy B , ChristopeitM , WillBet al. HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia . J. Clin. Invest.124 ( 3 ), 1158 – 1167 ( 2014 ).
  • Akalin A , Garrett-BakelmanFE , KormakssonMet al. Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia . PLoS Genet.8 ( 6 ), e1002781 ( 2012 ).
  • Aschenbrenner J , DrumM , TopalH , WielandM , MarxA . Direct sensing of 5-methylcytosine by polymerase chain reaction . Angew. Chem. Int. Ed. Engl.53 ( 31 ), 8154 – 8158 ( 2014 ).
  • Okano M , BellDW , HaberDA , LiE . DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development . Cell99 ( 3 ), 247 – 257 ( 1999 ).
  • Li E , BestorTH , JaenischR . Targeted mutation of the DNA methyltransferase gene results in embryonic lethality . Cell69 ( 6 ), 915 – 926 ( 1992 ).
  • Lei H , OhSP , OkanoMet al. De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells . Development122 ( 10 ), 3195 – 3205 ( 1996 ).
  • Ley TJ , DingL , WalterMJet al. DNMT3A mutations in acute myeloid leukemia . N. Engl. J. Med.363 ( 25 ), 2424 – 2433 ( 2010 ).
  • Grossmann V , HaferlachC , WeissmannSet al. The molecular profile of adult T-cell acute lymphoblastic leukemia: mutations in RUNX1 and DNMT3A are associated with poor prognosis in T-ALL . Genes Chromosomes Cancer52 ( 4 ), 410 – 422 ( 2013 ).
  • Bamford S , DawsonE , ForbesSet al. The COSMIC (catalogue of somatic mutations in cancer) database and website . Br. J. Cancer91 ( 2 ), 355 – 358 ( 2004 ).
  • Challen GA , SunD , JeongMet al. Dnmt3a is essential for hematopoietic stem cell differentiation . Nat. Genet.44 ( 1 ), 23 – 31 ( 2012 ).
  • Challen GA , SunD , MayleAet al. Dnmt3a and dnmt3b have overlapping and distinct functions in hematopoietic stem cells . Cell Stem Cell15 ( 3 ), 350 – 364 ( 2014 ).

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