829
Views
0
CrossRef citations to date
0
Altmetric
Editorial

Cell-Specific Gene Promoters are Marked by Broader Spans of H3K4me3 and are Associated with Robust Gene Expression Patterns

&
Pages 129-131 | Published online: 05 May 2015

References

  • Whyte WA , OrlandoDA , HniszDet al. Master transcription factors and mediator establish super-enhancers at key cell identity genes . Cell153 ( 2 ), 307 – 319 ( 2013 ).
  • Parker SC , StitzelML , TaylorDLet al. Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants . Proc. Natl Acad. Sci. USA110 ( 44 ), 17921 – 17926 ( 2013 ).
  • Hnisz D , AbrahamBJ , LeeTIet al. Super-enhancers in the control of cell identity and disease . Cell155 ( 4 ), 934 – 947 ( 2013 ).
  • Chapuy B , McKeownMR , LinCYet al. Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma . Cancer Cell24 ( 6 ), 777 – 790 ( 2013 ).
  • Xie W , SchultzMD , ListerRet al. Epigenomic analysis of multilineage differentiation of human embryonic stem cells . Cell153 ( 5 ), 1134 – 1148 ( 2013 ).
  • Jeong M , SunD , LuoMet al. Large conserved domains of low DNA methylation maintained by Dnmt3a . Nat. Genet.46 ( 1 ), 17 – 23 ( 2014 ).
  • Benayoun BA , PollinaEA , UcarDet al. H3K4me3 breadth is linked to cell identity and transcriptional consistency . Cell158 ( 3 ), 673 – 688 ( 2014 ).
  • Barski A , CuddapahS , CuiKet al. High-resolution profiling of histone methylations in the human genome . Cell129 ( 4 ), 823 – 837 ( 2007 ).
  • Dong X , GrevenMC , KundajeAet al. Modeling gene expression using chromatin features in various cellular contexts . Genome Biol.13 ( 9 ), R53 ( 2012 ).
  • Migliori V , MapelliM , GuccioneE . On WD40 proteins: propelling our knowledge of transcriptional control?Epigenetics7 ( 8 ), 815 – 822 ( 2012 ).
  • Yang YW , FlynnRA , ChenYet al. Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency . Elife3 , e02046 ( 2014 ).
  • Loven J , HokeHA , LinCYet al. Selective inhibition of tumor oncogenes by disruption of super-enhancers . Cell153 ( 2 ), 320 – 334 ( 2013 ).
  • Mendenhall EM , WilliamsonKE , ReyonDet al. Locus-specific editing of histone modifications at endogenous enhancers . Nat. Biotechnol.31 ( 12 ), 1133 – 1136 ( 2013 ).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.