Age-And Gender-Related Pattern of Methylation in the MT-RNR1 Gene

References

• Anderson S , BankierAT , BarrellBGet al. Sequence and organization of the human mitochondrial genome . Nature290 ( 5806 ), 457 – 465 ( 1981 ).
   PubMed Web of Science ®Google Scholar
• Clayton DA . Vertebrate mitochondrial DNA-a circle of surprises . Exp. Cell Res.255 ( 1 ), 4 – 9 ( 2000 ).
   PubMed Web of Science ®Google Scholar
• Christian BE , SpremulliLL . Mechanism of protein biosynthesis in mammalian mitochondria . Biochim. Biophys. Acta.1819 ( 9–10 ), 1035 – 1054 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Richman TR , RackhamO , FilipovskaA . Mitochondria: unusual features of the mammalian mitoribosome . Int. J. Biochem. Cell Biol.53 , 115 – 120 ( 2014 ).
   PubMed Web of Science ®Google Scholar
• Lightowlersa RN , RozanskaaA , Chrzanowska-LightowlersbZM . Mitochondrial protein synthesis: figuring the fundamentals, complexities and complications, of mammalian mitochondrial translation . FEBS Lett.588 ( 15 ), 2496 – 2503 ( 2014 ).
   PubMed Web of Science ®Google Scholar
• Sokol AM , SztolsztenerME , WasilewskiM , HeinzE , ChacinskaA . Mitochondrial protein translocases for survival and wellbeing . FEBS Lett.588 ( 15 ), 2484 – 2495 ( 2014 ).
   PubMed Web of Science ®Google Scholar
• O’Brien TW . Properties of human mitochondrial ribosomes . IUBMB Life55 ( 9 ), 505 – 513 ( 2003 ).
   PubMed Web of Science ®Google Scholar
• Eperon IC , AndersonS , NierlichDP . Distinctive sequence of human mitochondrial ribosomal RNA genes . Nature286 ( 5772 ), 460 – 467 ( 1980 ).
   PubMed Web of Science ®Google Scholar
• Fernández-Silva P , EnriquezJA , MontoyaJ . Replication and transcription of mammalian mitochondrial DNA . Exp. Physiol.88 ( 1 ), 41 – 56 ( 2003 ).
   PubMed Web of Science ®Google Scholar
• Manev H , DzitoyevaS . Progress in mitochondrial epigenetics . Biomol. Concepts4 ( 4 ), 381 – 389 ( 2013 ).
   PubMedGoogle Scholar
• Sadakierska-Chudy A , FrankowskaM , FilipM . Mitoepigenetics and drug addiction . Pharmacol. Ther.144 ( 2 ), 226 – 233 ( 2014 ).
   PubMed Web of Science ®Google Scholar
• Rebelo AP , WilliamsSL , MoraesCT . In vivo methylation of mtDNA reveals the dynamics of protein-mtDNA interactions . Nucleic Acids Res.37 ( 20 ), 6701 – 6715 ( 2009 ).
   PubMed Web of Science ®Google Scholar
• Shock LS , ThakkarPV , PetersonEJ , MoranRG , TaylorSM . DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria . Proc. Natl Acad. Sci. USA108 ( 9 ), 3630 – 3635 ( 2011 ).
   PubMed Web of Science ®Google Scholar
• Wong M , GertzB , ChestnutBA , MartinLJ . Mitochondrial DNMT3A and DNA methylation in skeletal muscle and CNS of transgenic mouse models of ALS . Front. Cell. Neurosci.7 , 279 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Chestnut BA , ChangQ , PriceA , LesuisseC , WongM , MartinLJ . Epigenetic regulation of motor neuron cell death through DNA methylation . J. Neurosci.31 ( 46 ), 16619 – 16636 ( 2011 ).
   PubMed Web of Science ®Google Scholar
• Bellizzi D , D’AquilaP , ScafoneTet al. The control region of mitochondrial DNA shows an unusual CpG and non-CpG methylation pattern . DNA Res.20 ( 6 ), 537 – 547 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Iacobazzi V , CastegnaA , InfantinoV , AndriaG . Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool . Mol. Genet. Metab.110 ( 1–2 ), 25 – 34 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Byun HM , PanniT , MottaVet al. Effects of airborne pollutants on mitochondrial DNA methylation . Part. Fibre Toxicol.10 , 18 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Infantino V , CastegnaA , IacobazziFet al. Impairment of methyl cycle affects mitochondrial methyl availability and glutathione level in Down’s syndrome . Mol. Genet. Metab.102 ( 3 ), 378 – 382 ( 2011 ).
   PubMed Web of Science ®Google Scholar
• Sun C , ReimersLL , BurkRD . Methylation of HPV16 genome CpG sites is associated with cervix precancer and cancer . Gynecol. Oncol.121 ( 1 ), 59 – 63 ( 2011 ).
   PubMed Web of Science ®Google Scholar
• Chen H , DzitoyevaS , ManevH . Effect of valproic acid on mitochondrial epigenetics . Eur. J. Pharmacol.690 ( 1–3 ), 51 – 59 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Pirola CJ , GianottiTF , BurgueñoALet al. Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease . Gut62 ( 9 ), 1356 – 1363 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Feng S , XiongL , JiZ , ChengW , YangH . Correlation between increased ND2 expression and demethylated displacement loop of mtDNA in colorectal cancer . Mol. Med. Rep.6 ( 1 ), 125 – 130 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Ghosh S , SenguptaS , ScariaV . Comparative analysis of human mitochondrial methylomes shows distinct patterns of epigenetic regulation in mitochondria . Mitochondrion18 , 58 – 62 ( 2014 ).
   PubMed Web of Science ®Google Scholar
• D’Aquila P , RoseG , BellizziD , PassarinoG . Epigenetics and aging . Maturitas74 ( 2 ), 130 – 136 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• De Rango F , MontesantoA , BerardelliMet al. To grow old in southern Italy: a comprehensive description of the old and oldest old in Calabria . Gerontology57 ( 4 ), 327 – 334 ( 2011 ).
   PubMed Web of Science ®Google Scholar
• Montesanto A , LaganiV , MartinoCet al. A novel, population-specific approach to define frailty . Age (Dordr)32 ( 3 ), 385 – 395 ( 2010 ).
   PubMedGoogle Scholar
• Zeschnigk M , BöhringerS , PriceEA , OnadimZ , MasshöferL , LohmannDR . A novel real-time PCR assay for quantitative analysis of methylated alleles (QAMA): analysis of the retinoblastoma locus . Nucleic Acids Res.32 ( 16 ), e125 ( 2004 ).
   PubMed Web of Science ®Google Scholar
• Agresti A . A survey of models for repeated ordered categorical response data . Stat. Med.8 ( 10 ), 1209 – 1224 ( 1989 ).
   PubMed Web of Science ®Google Scholar
• Wang J , GeigerH , RudolphKL . Immunoaging induced by hematopoietic stem cell aging . Curr. Opin. Immunol.23 ( 4 ), 532 – 536 ( 2011 ).
   PubMed Web of Science ®Google Scholar
• Wallace DC . Mitochondrial DNA mutations in disease and aging . Environ. Mol. Mutagen.51 ( 5 ), 440 – 450 ( 2010 ).
   PubMed Web of Science ®Google Scholar
• Lee HC , WeiYH . Mitochondria and aging . Adv. Exp. Med. Biol.942 , 311 – 327 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Bollati V , SchwartzJ , WrightRet al. Decline in genomic DNA methylation through aging in a cohort of elderly subjects . Mech. Ageing Dev.130 ( 4 ), 234 – 239 ( 2009 ).
   PubMed Web of Science ®Google Scholar
• Garagnani P , BacaliniMG , PirazziniCet al. Methylation of ELOVL2 gene as a new epigenetic marker of age . Aging Cell11 ( 6 ), 1132 – 1134 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Madrigano J , BaccarelliA , MittlemanMAet al. Aging and epigenetics: longitudinal changes in gene-specific DNA methylation . Epigenetics7 ( 1 ), 63 – 70 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Bellizzi D , D’AquilaP , MontesantoAet al. Global DNA methylation in old subjects is correlated with frailty . Age (Dordr)34 ( 1 ), 169 – 179 ( 2012 ).
   PubMedGoogle Scholar
• Oksuzyan A , JuelK , VaupelJW , ChristensenK . Men: good health and high mortality. Sex differences in health and aging . Aging Clin. Exp. Res.20 ( 2 ), 91 – 102 ( 2008 ).
   PubMed Web of Science ®Google Scholar
• De Benedictis G , RoseG , CarrieriGet al. Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans . FASEB J.13 ( 12 ), 1532 – 1536 ( 1999 ).
   PubMed Web of Science ®Google Scholar
• Camus MF , ClancyDJ , DowlingDK . Mitochondria, maternal inheritance, and male aging . Curr. Biol.22 ( 18 ), 1717 – 1721 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Bellizzi D , D’AquilaP , GiordanoM , MontesantoA , PassarinoG . Global DNA methylation levels are modulated by mitochondrial DNA variants . Epigenomics.4 ( 1 ), 17 – 27 ( 2012 ).
   PubMed Web of Science ®Google Scholar