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Special Report

Advances in Imaging The Innate and Adaptive Immune Response to Toxoplasma Gondii

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Pages 1321-1328 | Published online: 22 Sep 2010

Bibliography

  • Schlundt J , ToyofukuH, JansenJ, HerbstSA: Emerging food-borne zoonoses.Rev. Sci. Tech.23 , 513–533 (2004).
  • Barragan A , HitzigerN: Transepithelial migration by Toxoplasma.Subcell. Biochem.47 , 198–207 (2008).
  • Montoya JG , LiesenfeldO: Toxoplasmosis.Lancet363 , 1965–1976 (2004).
  • Denkers EY , GazzinelliRT: Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection.Clin. Microbiol. Rev.11 , 569–588 (1998).
  • Gazzinelli RT , HayashiS, WysockaMet al. : Role of IL-12 in the initiation of cell mediated immunity by Toxoplasma gondii and its regulation by IL-10 and nitric oxide.J. Eukaryot. Microbiol.41 , 9S (1994).
  • Gazzinelli RT , WysockaM, HayashiSet al. : Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii.J. Immunol.153 , 2533–2543 (1994).
  • Denkers EY , ButcherBA, Del RioL, BennounaS: Neutrophils, dendritic cells and Toxoplasma.Int. J. Parasitol.34 , 411–421 (2004).
  • Hunter CA , RemingtonJS: Immunopathogenesis of toxoplasmic encephalitis.J. Infect. Dis.170 , 1057–1067 (1994).
  • Suzuki Y : Host resistance in the brain against Toxoplasma gondii.J. Infect. Dis.185(Suppl. 1) , S58–S65 (2002).
  • Bousso P , RobeyE: Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes.Nat. Immunol.4 , 579–585 (2003).
  • Chtanova T , SchaefferM, HanSJet al. : Dynamics of neutrophil migration in lymph nodes during infection.Immunity29(3) , 487–496 (2008).
  • Dzierszinski F , PepperM, StumhoferJSet al. : Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells.Infect. Immun.75 , 5200–5209 (2007).
  • John B , HarrisTH, TaitEDet al. : Dynamic Imaging of CD8+ T cells and dendritic cells during infection with Toxoplasma gondii.PLoS Pathog.5 , e1000505 (2009).
  • Wilson EH Harris HT , MrassP, JohnBet al.: Behavior of parasite-specific effector CD8+ T cells in the brain and visualization of a kinesis-associated system of reticular fibers.Immunity30 , 300–311 (2009).
  • Hitziger N , DellacasaI, AlbigerB, BarraganA: Dissemination of Toxoplasma gondii to immunoprivileged organs and role of Toll/interleukin-1 receptor signalling for host resistance assessed by in vivo bioluminescence imaging.Cell Microbiol.7 , 837–848 (2005).
  • Coombes JL , RobeyEA: Dynamic imaging of host–pathogen interactions in vivo.Nat. Rev. Immunol.10 , 353–364 (2010).
  • Barragan A , BrossierF, SibleyLD: Transepithelial migration of Toxoplasma gondii involves an interaction of intercellular adhesion molecule 1 (ICAM-1) with the parasite adhesin MIC2.Cell Microbiol.7 , 561–568 (2005).
  • Chtanova T , HanSJ, SchaefferMet al. : Dynamics of T cell, antigen-presenting cell, and pathogen interactions during recall responses in the lymph node.Immunity31 , 342–355 (2009).
  • Dellacasa-Lindberg I , HitzigerN, BarraganA: Localized recrudescence of Toxoplasma infections in the central nervous system of immunocompromised mice assessed by in vivo bioluminescence imaging.Microbes Infect.9 , 1291–1298 (2007).
  • Goldszmid RS , CoppensI, LevAet al. : Host ER–parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells.J. Exp. Med.206(2) , 399–410 (2009).
  • Pepper M , DzierszinskiF, CrawfordA, HunterCA, RoosD: Development of a system to study CD4+-T-cell responses to transgenic ovalbumin-expressing Toxoplasma gondii during toxoplasmosis.Infect. Immun.72 , 7240–7246 (2007).
  • Schaeffer M , HanSJ, ChtanovaTet al. : Dynamic imaging of T cell-parasite interactions in the brains of mice chronically infected with Toxoplasma gondii.J. Immunol.182 , 6379–6393 (2009).
  • Boothroyd JC : Toxoplasma gondii: 25 years and 25 major advances for the field.Int. J. Parasitol.39 , 935–946 (2009).
  • Tait ED , HunterCA: Advances in understanding immunity to Toxoplasma gondii.Mem. Inst. Oswaldo Cruz.104 , 201–210 (2009).
  • Dubremetz JF , FergusonDJ: The role played by electron microscopy in advancing our understanding of Toxoplasma gondii and other apicomplexans.Int. J. Parasitol.39 , 883–893 (2009).
  • Dzierszinski FS , HunterCA: Advances in the use of genetically engineered parasites to study immunity to Toxoplasma gondii.Parasite Immunol.30 , 235–244 (2008).
  • Gubbels MJ , StriepenB: Studying the cell biology of apicomplexan parasites using fluorescent proteins.Microsc. Microanal.10 , 568–579 (2004).
  • Striepen B , HeCY, MatrajtM, SoldatiD, RoosDS: Expression, selection, and organellar targeting of the green fluorescent protein in Toxoplasma gondii.Mol. Biochem. Parasitol.92 , 325–338 (1998).
  • Gubbels MJ , LiC, StriepenB: High-throughput growth assay for Toxoplasma gondii using yellow fluorescent protein.Antimicrob. Agents Chemother.47 , 309–316 (2003).
  • Gubbels MJ , WiefferM, StriepenB: Fluorescent protein tagging in Toxoplasma gondii: identification of a novel inner membrane complex component conserved among Apicomplexa.Mol. Biochem. Parasitol.137 , 99–110 (2004).
  • Wille U , VillegasEN, StriepenB, RoosDS, HunterCA: Interleukin-10 does not contribute to the pathogenesis of a virulent strain of Toxoplasma gondii.Parasite Immunol.23 , 291–296 (2001).
  • Courret N , DarcheS, SonigoPet al. : CD11c- and CD11b-expressing mouse leukocytes transport single Toxoplasma gondii tachyzoites to the brain.Blood107 , 309–316 (2006).
  • Lambert H , HitzigerN, DellacasaI, SvenssonM, BarraganA: Induction of dendritic cell migration upon Toxoplasma gondii infection potentiates parasite dissemination.Cell Microbiol.8 , 1611–1623 (2006).
  • Unno A , SuzukiK, BatanovaTet al. : Visualization of Toxoplasma gondii stage conversion by expression of stage-specific dual fluorescent proteins.Parasitology136 , 579–588 (2009).
  • Saeij JP , BoyleJP, GriggME, ArrizabalagaG, BoothroydJC: Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains.Infect. Immun.73 , 695–702 (2005).
  • Hutchens M , LukerGD: Applications of bioluminescence imaging to the study of infectious diseases.Cell Microbiol.9 , 2315–2322 (2007).
  • Lambert H , VutovaPP, AdamsWC, LoreK, BarraganA: The Toxoplasma gondii-shuttling function of dendritic cells is linked to the parasite genotype.Infect. Immun.77 , 1679–1688 (2009).
  • Koshy AA , FoutsAE, LodoenMBet al. : Toxoplasma secreting Cre recombinase for analysis of host–parasite interactions.Nat. Methods7(4) , 307–309 (2010).
  • Boothroyd JC , DubremetzJF: Kiss and spit: the dual roles of Toxoplasma rhoptries.Nat. Rev. Microbiol.6 , 79–88 (2008).
  • Sauer B : Inducible gene targeting in mice using the Cre/lox system.Methods14 , 381–392 (1998).
  • Gubbels MJ , StriepenB, ShastriN, TurkozM, RobeyEA: Class I major histocompatibility complex presentation of antigens that escape from the parasitophorous vacuole of Toxoplasma gondii.Infect. Immun.73 , 703–711 (2005).
  • McSorley SJ , AschS, CostalongaM, ReinhardtRL, JenkinsMK: Tracking salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection.Immunity16 , 365–377 (2002).
  • Pope CS , KimK, MarzoAet al. : Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection.J. Immunol.166 , 3402–3409 (2001).
  • Kumar S , TarletonRL: Antigen-specific Th1 but not Th2 cells provide protection from lethal Trypanosoma cruzi infection in mice.J. Immunol.166 , 4596–4603 (2001).
  • Pepper M , DzierszinskiF, WilsonEet al. : Plasmacytoid dendritic cells are activated by Toxoplasma gondii to present antigen and produce cytokines.J. Immunol.180 , 6229–6236 (2008).
  • Blanchard N , GonzalezF, SchaefferMet al. : Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum.Nat. Immunol.9 , 937–944 (2008).
  • Frickel EM , SahooN, HoppJet al. : Parasite stage-specific recognition of endogenous Toxoplasma gondii-derived CD8+ T cell epitopes.J. Infect. Dis.198 , 1625–1633 (2008).
  • Wilson DC , GrotenbregGM, LiuKet al. : Differential regulation of effector- and central-memory responses to Toxoplasma gondii infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells.PLoS Pathog.6 , e1000815 (2010).
  • Kirak O , FrickelEM, GrotenbregGMet al. : Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT.Science328 , 243–248 (2010).
  • Mempel TR , HenricksonSE, Von AndrianUH: T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases.Nature427 , 154–159 (2004).
  • Miller MJ , SafrinaO, ParkerI, CahalanMD: Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes.J. Exp. Med.200 , 847–856 (2004).
  • Miller MJ , WeiSH, CahalanMD, ParkerI: Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy.Proc. Natl Acad. Sci. USA100 , 2604–9260 (2003).
  • Hickman HD , TakedaK, SkonCNet al. : Direct priming of antiviral CD8+ T cells in the peripheral interfollicular region of lymph nodes.Nat. Immunol.9 , 155–165 (2008).
  • Junt T , MosemanEA, IannaconeMet al. : Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells.Nature450 , 110–114 (2007).
  • Ng LG , HsuA, MandellMAet al. : Migratory dermal dendritic cells act as rapid sensors of protozoan parasites.PLoS Pathog.4 , e1000222 (2008).
  • Peters NC , EgenJG, SecundinoNet al. : In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies.Science321 , 970–974 (2008).
  • Liu CH , FanYT, DiasAet al. : Cutting edge: dendritic cells are essential for in vivo IL-12 production and development of resistance against Toxoplasma gondii infection in mice.J. Immunol.177 , 31–35 (2006).
  • Persson CM , LambertH, VutovaPPet al. : Transmission of Toxoplasma gondii from infected dendritic cells to natural killer cells.Infect. Immun.77 , 970–976 (2009).
  • Tait ED , JordanKA, DupontCDet al. : Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells.J. Immunol.185(3) , 1502–1512 (2010).
  • Reinhardt RL , HongS, KangSJ, WangZE, LocksleyRM: Visualization of IL-12/23p40 in vivo reveals immunostimulatory dendritic cell migrants that promote Th1 differentiation.J. Immunol.177 , 1618–1627 (2006).
  • Suzuki Y : Immunopathogenesis of cerebral toxoplasmosis.J. Infect. Dis.186(Suppl. 2) , S234–S240 (2002).
  • Chieppa M , RescignoM, HuangAY, GermainRN: Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement.J. Exp. Med.203 , 2841–2852 (2006).
  • Kim JV , KangSS, DustinML, McGavernDB: Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis.Nature457 , 191–195 (2009).
  • Beattie L , PeltanA, MaroofAet al. : Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells.PLoS Pathog.6 , e1000805 (2010).

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