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Systematic review

Coenzyme Q10 in breast cancer care

Pages 1035-1041 | Received 14 Dec 2016, Accepted 21 Feb 2017, Published online: 08 May 2017

References

  • Bahar M , KhaghaniS, PasalarPet al. Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model. Nutr. J.9, 62 (2010).
  • Cooney RV , DaiQ, GaoYTet al. Low plasma coenzyme Q(10) levels and breast cancer risk in Chinese women. Cancer Epidemiol. Biomarkers Prevent.20(6), 1124–1130 (2011).
  • Complementary treatments highlighted at recent meeting. Oncology (Williston Park, N.Y.)13(2), 166 (1999).
  • Hill GJ , ShriverBJ, ArnettDB. Examining intentions to use CoQ10 amongst breast cancer patients. Am. J. Health Behav.30(3), 313–321 (2006).
  • Sivak LA , Askol’skiiAV, Lial’kinSA, KlimanovM, MaidanevichNN, KasapNV. Cardiotoxicity of conservative treatment of solid tumors. Lik. Sprava (3–4), 51–59 (2011).
  • Portakal O , OzkayaO, Erden InalM, BozanB, KosanM, SayekI. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin. Biochem.33(4), 279–284 (2000).
  • Sinatra ST . “Care,” cancer and coenzyme Q10. J. Am. Coll. Cardiol.33(3), 897–899 (1999).
  • Greenlee H , ShawJ, LauYK, NainiA, MaurerM. Lack of effect of coenzyme q10 on doxorubicin cytotoxicity in breast cancer cell cultures. Integr. Cancer Ther.11(3), 243–250 (2012).
  • Perumal SS , ShanthiP, SachdanandamP. Augmented efficacy of tamoxifen in rat breast tumorigenesis when gavaged along with riboflavin, niacin, and CoQ10: effects on lipid peroxidation and antioxidants in mitochondria. Chem. Bio. Interact.152(1), 49–58 (2005).
  • Lockwood K , MoesgaardS, FolkersK. Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10. Biochem. Biophys. Res. Communs.199(3), 1504–1508 (1994).
  • Lockwood K , MoesgaardS, HaniokaT, FolkersK. Apparent partial remission of breast cancer in ‘high risk’ patients supplemented with nutritional antioxidants, essential fatty acids and coenzyme Q10. Mol. Aspects Med.15(Suppl.), s231–s240 (1994).
  • Lockwood K , MoesgaardS, YamamotoT, FolkersK. Progress on therapy of breast cancer with vitamin Q10 and the regression of metastases. Biochem. Biophys. Res. Communs.212(1), 172–177 (1995).
  • Premkumar VG , YuvarajS, VijayasarathyK, GangadaranSG, SachdanandamP. Effect of coenzyme Q10, riboflavin and niacin on serum CEA and CA 15-3 levels in breast cancer patients undergoing tamoxifen therapy. Biol. Pharm. Bull.30(2), 367–370 (2007).
  • Premkumar VG , YuvarajS, ShanthiP, SachdanandamP. Co-enzyme Q10, riboflavin and niacin supplementation on alteration of DNA repair enzyme and DNA methylation in breast cancer patients undergoing tamoxifen therapy. Br. J. Nutr.100(6), 1179–1182 (2008).
  • Premkumar VG , YuvarajS, SathishS, ShanthiP, SachdanandamP. Anti-angiogenic potential of coenzymeQ10, riboflavin and niacin in breast cancer patients undergoing tamoxifen therapy. Vascul. Pharmacol.48(4–6), 191–201 (2008).
  • Premkumar VG , YuvarajS, VijayasarathyK, GangadaranSG, SachdanandamP. Serum cytokine levels of interleukin-1beta, −6, −8, tumour necrosis factor-alpha and vascular endothelial growth factor in breast cancer patients treated with tamoxifen and supplemented with co-enzyme Q(10), riboflavin and niacin. Basic Clin. Pharmacol. Toxicol.100(6), 387–391 (2007).
  • Yuvaraj S , PremkumarVG, VijayasarathyK, GangadaranSG, SachdanandamP. Augmented antioxidant status in tamoxifen treated postmenopausal women with breast cancer on co-administration with coenzyme Q10, niacin and riboflavin. Cancer Chemother. Pharmacol.61(6), 933–941 (2008).
  • Yuvaraj S , PremkumarVG, ShanthiP, VijayasarathyK, GangadaranSG, SachdanandamP. Effect of coenzyme Q(10), riboflavin and niacin on tamoxifen treated postmenopausal breast cancer women with special reference to blood chemistry profiles. Breast Cancer Res. Treat.114(2), 377–384 (2009).
  • Yuvaraj S , PremkumarVG, VijayasarathyK, GangadaranSG, SachdanandamP. Ameliorating effect of coenzyme Q10, riboflavin and niacin in tamoxifen-treated postmenopausal breast cancer patients with special reference to lipids and lipoproteins. Clin. Biochem.40(9–10), 623–628 (2007).
  • Sachdanandam P . Antiangiogenic and hypolipidemic activity of coenzyme Q10 supplementation to breast cancer patients undergoing tamoxifen therapy. Biofactors32(1–4), 151–159 (2008).
  • Lesser GJ , CaseD, StarkNet al. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer. J. Support. Oncol.11(1), 31–42 (2013).
  • Iwase S , KawaguchiT, YotsumotoDet al. Efficacy and safety of an amino acid jelly containing coenzyme Q10 and L-carnitine in controlling fatigue in breast cancer patients receiving chemotherapy: a multi-institutional, randomized, exploratory trial (JORTC-CAM01). Support. Care Cancer24(2), 637–646 (2016).
  • Bjorklund G . The Adjuvant Nutritional Intervention in Cancer (ANICA) trial. Nutr. Cancer67(8), 1355–1358 (2015).
  • Chai W , CooneyRV, FrankeAAet al. Plasma coenzyme Q10 levels and postmenopausal breast cancer risk: the multiethnic cohort study. Cancer Epidemiol. Biomarkers Prevent.19(9), 2351–2356 (2010).

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