Lactic Dehydrogenase to Albumin Ratio in Prediction of Unresectable Pancreatic Cancer with Intervention Chemotherapy

References

• Siegel RL , MillerKD, JemalA. Cancer statistics: 2017. CA Cancer J. Clin.67(1), 7–30 (2017).
   PubMed Web of Science ®Google Scholar
• Pu N , LvY, ZhaoGet al. Survival prediction in pancreatic cancer patients with no distant metastasis: a large-scale population-based estimate. Future Oncol.14(2), 165–175 (2018).
   PubMed Web of Science ®Google Scholar
• Chen Y , WangXL, WangJHet al. Transarterial infusion with gemcitabine and oxaliplatin for the treatment of unresectable pancreatic cancer. Anticancer Drugs25(8), 958–963 (2014).
   PubMed Web of Science ®Google Scholar
• Saka B , BalciS, BasturkOet al. Pancreatic ductal adenocarcinoma is spread to the peripancreatic soft tissue in the majority of resected cases: rendering the AJCC T-stage protocol (7th edition) inapplicable and insignificant: a size-based staging system (pT1: </=2: pT2: > 2-</=4: pT3: > 4 cm) is more valid and clinically relevant. Ann. Surg. Oncol.23(6), 2010–2018 (2016).
   PubMed Web of Science ®Google Scholar
• Ferreira LM , HebrantA, DumontJE. Metabolic reprogramming of the tumor. Oncogene31(36), 3999–4011 (2012).
   PubMed Web of Science ®Google Scholar
• Li G , GaoJ, TaoYLet al. Increased pretreatment levels of serum LDH and ALP as poor prognostic factors for nasopharyngeal carcinoma. Chin. J. Cancer31(4), 197–206 (2012).
   PubMedGoogle Scholar
• Hirschhaeuser F , SattlerUG, Mueller-KlieserW. Lactate: a metabolic key player in cancer. Cancer Res.71(22), 6921–6925 (2011).
   PubMed Web of Science ®Google Scholar
• Rong Y , WuW, NiXet al. Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells. Tumour Biol.34(3), 1523–1530 (2013).
   PubMedGoogle Scholar
• Tas F , AykanF, AliciS, KaytanE, AydinerA, TopuzE. Prognostic factors in pancreatic carcinoma: serum LDH levels predict survival in metastatic disease. Am. J. Clin. Oncol.24(6), 547–550 (2001).
   PubMed Web of Science ®Google Scholar
• Danner BC , DidilisVN, WiemeyerSet al. Long-term survival is linked to serum LDH and partly to tumour LDH-5 in NSCLC. Anticancer Res.30(4), 1347–1351 (2010).
   PubMed Web of Science ®Google Scholar
• Wu SJ , LinYX, YeH, XiongXZ, LiFY, ChengNS. Prognostic value of alkaline phosphatase: gamma-glutamyl transpeptidase and lactate dehydrogenase in hepatocellular carcinoma patients treated with liver resection. Int. J. Surg.36(Pt A), 143–151 (2016).
   PubMedGoogle Scholar
• Don BR , KaysenG. Serum albumin: relationship to inflammation and nutrition. Semin. Dial.17(6), 432–437 (2004).
   PubMed Web of Science ®Google Scholar
• Gupta D , LisCG. Pretreatment serum albumin as a predictor of cancer survival: a systematic review of the epidemiological literature. Nutr. J.9, 69 (2010).
   PubMed Web of Science ®Google Scholar
• He X , GuoS, ChenDet al. Preoperative albumin to globulin ratio (AGR) as prognostic factor in renal cell carcinoma. J. Cancer8(2), 258–265 (2017).
   PubMed Web of Science ®Google Scholar
• Xu WZ , LiF, XuZKet al. Preoperative albumin-to-globulin ratio and prognostic nutrition index predict prognosis for glioblastoma. Onco. Targets Ther.10, 725–733 (2017).
   PubMed Web of Science ®Google Scholar
• Pu N , GaoS, XuYet al. Alkaline phosphatase-to-albumin ratio as a prognostic indicator in pancreatic ductal adenocarcinoma after curative resection. J. Cancer8(16), 3362–3370 (2017).
   PubMed Web of Science ®Google Scholar
• Kanda M , FujiiT, KoderaY, NagaiS, TakedaS, NakaoA. Nutritional predictors of postoperative outcome in pancreatic cancer. Br. J. Surg.98(2), 268–274 (2011).
   PubMed Web of Science ®Google Scholar
• Camp RL , Dolled-FilhartM, RimmDL. X-tile: a new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization. Clin. Cancer Res.10(21), 7252–7259 (2004).
   PubMed Web of Science ®Google Scholar
• Zeng Q , XueN, DaiDet al. A nomogram based on inflammatory factors C-reactive protein and fibrinogen to predict the prognostic value in patients with resected non-small cell lung cancer. J. Cancer8(5), 744–753 (2017).
   PubMed Web of Science ®Google Scholar
• Zhang J , YaoYH, LiBG, YangQ, ZhangPY, WangHT. Prognostic value of pretreatment serum lactate dehydrogenase level in patients with solid tumors: a systematic review and meta-analysis. Sci. Rep.5, 9800 (2015).
   PubMed Web of Science ®Google Scholar
• Arroyo V , Garcia-MartinezR, SalvatellaX. Human serum albumin: systemic inflammation: and cirrhosis. J. Hepatol.61(2), 396–407 (2014).
   PubMed Web of Science ®Google Scholar
• Grunnet M , SorensenJB. Carcinoembryonic antigen (CEA) as tumor marker in lung cancer. Lung Cancer76(2), 138–143 (2012).
   PubMed Web of Science ®Google Scholar
• Shimada H , NoieT, OhashiM, ObaK, TakahashiY. Clinical significance of serum tumor markers for gastric cancer: a systematic review of literature by the Task Force of the Japanese Gastric Cancer Association. Gastric Cancer17(1), 26–33 (2014).
   PubMed Web of Science ®Google Scholar
• Nazli O , BozdagAD, TansugT, KirR, KaymakE. The diagnostic importance of CEA and CA 19-9 for the early diagnosis of pancreatic carcinoma. Hepatogastroenterology47(36), 1750–1752 (2000).
   PubMedGoogle Scholar
• Zhou G , LiuX, WangXet al. Combination of preoperative CEA and CA19-9 improves prediction outcomes in patients with resectable pancreatic adenocarcinoma: results from a large follow-up cohort. Onco. Targets Ther.10, 1199–1206 (2017).
   PubMed Web of Science ®Google Scholar
• Imaoka H , MizunoN, HaraKet al. Prognostic impact of carcinoembryonic antigen (CEA) on patients with metastatic pancreatic cancer: a retrospective cohort study. Pancreatology16(5), 859–864 (2016).
   PubMed Web of Science ®Google Scholar
• Martin HL , OharaK, KiberuA, Van HagenT, DavidsonA, KhattakMA. Prognostic value of systemic inflammation-based markers in advanced pancreatic cancer. Intern. Med. J.44(7), 676–682 (2014).
   PubMed Web of Science ®Google Scholar
• Liu Z , JinK, GuoMet al. Prognostic value of the CRP/Alb ratio: a novel inflammation-based score in pancreatic cancer. Ann. Surg. Oncol.24(2), 561–568 (2017).
   PubMed Web of Science ®Google Scholar