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Future Oncology Volume 19, 2023 - Issue 38
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Clinical Trial Protocol

Sintilimab Combined Neoadjuvant Intraperitoneal And Systemic Chemotherapy in Gastric Cancer With Peritoneal Metastasis

Hong Yuan1 Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, ChinaORCID Iconhttps://orcid.org/0000-0002-1492-5173
ORCID Icon,
Sheng Lu2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Min Shi1 Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Zhongyin Yang2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Wentao Liu2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Zhentian Ni2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Xuexin Yao2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Zichen Hua2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Runhua Feng2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Yanan Zheng2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Zhenqiang Wang2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Birendra Kumar Sah2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Mingmin Chen2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Zhenglun Zhu2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Changyu He2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Chen Li2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
,
Jun Zhang1 Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China;3 State Key Laboratory of Oncogenes & Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai200025, China
,
Chao Yan2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, ChinaCorrespondence[email protected]
,
Min Yan2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
&
Zhenggang Zhu2 Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai200025, China
 show all
Pages 2517-2523 | Received 24 Jul 2022, Accepted 04 May 2023, Published online: 22 May 2023

References

  • Sung H , FerlayJ, SiegelRLet al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin.71(3), 209–249 (2021).
  • Xia C , DongX, LiHet al. Cancer statistics in China and United States, 2022: profiles, trends, and determinants. Chin. Med. J.135(5), 584–590 (2022).
  • Cortés-Guiral D , HübnerM, AlyamiMet al. Primary and metastatic peritoneal surface malignancies. Nat. Rev. Dis. Primers7(1), 91 (2021).
  • Nashimoto A , AkazawaK, IsobeYet al. Gastric cancer treated in 2002 in Japan: 2009 annual report of the JGCA nationwide registry. Gastric Cancer16(1), 1–27 (2013).
  • Thomassen I , van GestelYR, van RamshorstBet al. Peritoneal carcinomatosis of gastric origin: a population-based study on incidence, survival and risk factors. Int. J. Cancer134(3), 622–628 (2014).
  • Foster JM , ZhangC, RehmanS, SharmaP, AlexanderHR. The contemporary management of peritoneal metastasis: a journey from the cold past of treatment futility to a warm present and a bright future. CA Cancer J. Clin.73(1), 49–71 (2023).
  • Ishigami H , FujiwaraY, FukushimaRet al. Phase III trial comparing intraperitoneal and intravenous paclitaxel plus S-1 versus cisplatin plus S-1 in patients with gastric cancer with peritoneal metastasis: PHOENIX-GC trial. J. Clin. Oncol.36(19), 1922–1929 (2018).
  • Lu S , YangZY, YanCet al. A phase III trial of neoadjuvant intraperitoneal and systemic chemotherapy for gastric cancer with peritoneal metastasis. Future Oncol.18(10), 1175–1183 (2022).
  • Janjigian YY , ShitaraK, MoehlerMet al. First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial. Lancet398(10294), 27–40 (2021).
  • Salas-Benito D , Pérez-GraciaJL, Ponz-SarviséMet al. Paradigms on immunotherapy combinations with chemotherapy. Cancer Disc.11(6), 1353–1367 (2021).
  • Lee HE , ParkKU, YooSBet al. Clinical significance of intratumoral HER2 heterogeneity in gastric cancer. Eur. J. Cancer49(6), 1448–1457 (2013).
  • Röcken C , AmallrajaA, HalskeCet al. Multiscale heterogeneity in gastric adenocarcinoma evolution is an obstacle to precision medicine. Genome Med.13(1), 177 (2021).
  • Joshi SS , BadgwellBD. Current treatment and recent progress in gastric cancer. CA Cancer J. Clin.71(3), 264–279 (2021).
  • The Chicago Consensus on peritoneal surface malignancies: management of gastric metastases. Cancer126(11), 2541–2546 (2020).
  • Ceelen W , BraetH, van RamshorstG, WillaertW, RemautK. Intraperitoneal chemotherapy for peritoneal metastases: an expert opinion. Expert Opin. Drug Deliv.17(4), 511–522 (2020).
  • Fujiwara Y , TakiguchiS, NakajimaKet al. Neoadjuvant intraperitoneal and systemic chemotherapy for gastric cancer patients with peritoneal dissemination. Ann. Surg. Oncol.18(13), 3726–3731 (2011).
  • Shi M , YangZ, LuSet al. Oxaliplatin plus S-1 with intraperitoneal paclitaxel for the treatment of Chinese advanced gastric cancer with peritoneal metastases. BMC Cancer21(1), 1344 (2021).

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