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Priority Paper Evaluation

Significance of Serum DKK1 as a Diagnostic Biomarker in Hepatocellular Carcinoma

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Pages 1525-1528 | Published online: 12 Dec 2012

References

  • Shen Q , FanJ, YangXRet al. Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study. Lancet Oncol. 13(8), 817–826 (2012).
  • Ferlay J , ShinHR, BrayF, FormanD, MathersC, ParkinDM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008.Int. J. Cancer127(12), 2893–2917 (2010).
  • Jemal A , BrayF, CenterMM, FerlayJ, WardE, FormanD. Global cancer statistics.CA: Cancer J. Clin.61(2), 69–90 (2011).
  • Bae JS , ParkSJ, ParkKBet al. Acute exacerbation of hepatitis in liver cirrhosis with very high levels of α-fetoprotein but no occurrence of hepatocellular carcinoma. Korean J. Int. Med. 20(1), 80–85 (2005).
  • Soresi M , MagliarisiC, CampagnaPet al. Usefulness of α-fetoprotein in the diagnosis of hepatocellular carcinoma. Anticancer Res. 23(2C), 1747–1753 (2003).
  • Khien VV , MaoHV, ChinhTTet al. Clinical evaluation of lentil lectin-reactive α-fetoprotein-L3 in histology-proven hepatocellular carcinoma. Int. J. Biol. Markers 16(2), 105–111 (2001).
  • Sengupta B , SiddiqiSA. Hepatocellular carcinoma: important biomarkers and their significance in molecular diagnostics and therapy.Curr. Med. Chem.19(22), 3722–3729 (2012).
  • Malaguarnera G , GiordanoM, PaladinaI, BerrettaM, CappellaniA, MalaguarneraM. Serum markers of hepatocellular carcinoma.Dig. Dis. Sci.55(10), 2744–2755 (2010).
  • Mann CD , NealCP, GarceaG, MansonMM, DennisonAR, BerryDP. Prognostic molecular markers in hepatocellular carcinoma: a systematic review.Eur. J. Cancer43(6), 979–992 (2007).
  • Spangenberg HC , ThimmeR, BlumHE. Serum markers of hepatocellular carcinoma.Semin. Liver Dis.26(4), 385–390 (2006).
  • Cui R , HeJ, ZhangFet al. Diagnostic value of protein induced by vitamin K absence (PIVKAII) and hepatoma-specific band of serum γ-glutamyl transferase (GGTII) as hepatocellular carcinoma markers complementary to α-fetoprotein. Br. J. Cancer 88(12), 1878–1882 (2003).
  • Hippo Y , WatanabeK, WatanabeAet al. Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma. Cancer Res. 64(7), 2418–2423 (2004).
  • Shimizu A , ShirakiK, ItoTet al. Sequential fluctuation pattern of serum des-γ-carboxy prothrombin levels detected by high-sensitive electrochemiluminescence system as an early predictive marker for hepatocellular carcinoma in patients with cirrhosis. Int. J. Mol. Med. 9(3), 245–250 (2002).
  • Zender L , KubickaS. Molecular pathogenesis and targeted therapy of hepatocellular carcinoma.Onkologie31(10), 550–555 (2008).
  • Wong CM , NgIO. Molecular pathogenesis of hepatocellular carcinoma.Liver Int.28(2), 160–174 (2008).
  • Takigawa Y , BrownAM. Wnt signaling in liver cancer.Curr. Drug Targets9(11), 1013–1024 (2008).
  • Tung EK , MakCK, FatimaSet al. Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma. Liver Int. 31(10), 1494–1504 (2011).
  • Sato N , YamabukiT, TakanoAet al. Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy. Cancer Res. 70(13), 5326–5336 (2010).
  • Yu B , YangX, XuYet al. Elevated expression of DKK1 is associated with cytoplasmic/nuclear β-catenin accumulation and poor prognosis in hepatocellular carcinomas. J. Hepatol. 50(5), 948–957 (2009).
  • Gonzalez-Sancho JM , AguileraO, GarciaJMet al. The Wnt antagonist DICKKOPF-1 gene is a downstream target of β-catenin/TCF and is downregulated in human colon cancer. Oncogene 24(6), 1098–1103 (2005).

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