323
Views
0
CrossRef citations to date
0
Altmetric
Editorial

The Mechanisms Behind Human Papillomavirus-Associated Cancer: The Role of Pdz Recognition in Malignant Progression

, , , &
Pages 675-677 | Published online: 09 Jun 2011

Bibliography

  • Zur Hausen H : Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis.J. Natl Cancer Inst.92(9) , 690–698 (2000).
  • Zur Hausen H : Papillomaviruses and cancer: from basic studies to clinical application.Nat. Rev. Cancer2(5) , 342–350 (2002).
  • Munoz N , BoschFX, CastellsagueX et al.: Against which human papillomavirus types shall we vaccinate and screen? The international perspective.Int. J. Cancer111(2) , 278–285 (2004).
  • Bouvard V , BaanR, StraifK et al.: A review of human carcinogens – part B: biological agents.Lancet Oncol.10(4) , 321–322 (2009).
  • Richardson H , KelsallG, TellierP et al.: The natural history of type-specific human papillomavirus infections in female university students.Cancer Epidemiol. Biomarkers Prev.12(6) , 485–490 (2003).
  • Munger K , BasileJR, DuensingS et al.: Biological activities and molecular targets of the human papillomavirus E7 oncoprotein.Oncogene20(54) , 7888–7898 (2001).
  • Mantovani F , BanksL: The human papillomavirus E6 protein and its contribution to malignant progression.Oncogene20(54) , 7874–7887 (2001).
  • Scheffner M , HuibregtseJM, VierstraRD, HowleyPM: The HPV-16 E6 and E6–AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53.Cell75(3) , 495–505 (1993).
  • Nguyen ML , NguyenMM, LeeD, GriepAE, LambertPF: The PDZ ligand domain of the human papillomavirus type 16 E6 protein is required for E6‘s induction of epithelial hyperplasia in vivo.J. Virol.77(12) , 6957–6964 (2003).
  • Lee C , LaiminsLA: Role of the PDZ domain-binding motif of the oncoprotein E6 in the pathogenesis of human papillomavirus type 31.J. Virol.78(22) , 12366–12377 (2004).
  • Thomas M , NarayanN, PimD et al.: Human papillomaviruses, cervical cancer and cell polarity.Oncogene27(55) , 7018–7030 (2008).
  • Kiyono T , HiraiwaA, FujitaM, HayashiY, AkiyamaT, IshibashiM: Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein.Proc. Natl Acad. Sci. USA94(21) , 11612–11616 (1997).
  • Lee SS , WeissRS, JavierRT: Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein.Proc. Natl Acad. Sci. USA94(13) , 6670–6675 (1997).
  • Handa K , YugawaT, Narisawa-SaitoM, OhnoS, FujitaM, KiyonoT: E6AP-dependent degradation of Dlg4/PSD95 by high-risk human papillomavirus type 18 E6 protein.J. Virol.81(3) , 1379–1389 (2007).
  • Nakagawa S , HuibregtseJM: Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase.Mol. Cell. Biol.20(21) , 8244–8253 (2000).
  • Glaunsinger BA , LeeSS, ThomasM, BanksL, JavierR: Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteins.Oncogene19(46) , 5270–5280 (2000).
  • Thomas M , GlaunsingerB, PimD, JavierR, BanksL: HPV E6 and MAGUK protein interactions: determination of the molecular basis for specific protein recognition and degradation.Oncogene20(39) , 5431–5439 (2001).
  • Thomas M , LauraR, HepnerK et al.: Oncogenic human papillomavirus E6 proteins target the MAGI-2 and MAGI-3 proteins for degradation.Oncogene21(33) , 5088–5096 (2002).
  • Lee SS , GlaunsingerB, MantovaniF, BanksL, JavierRT: Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins.J. Virol.74(20) , 9680–9693 (2000).
  • Jing M , BohlJ, BrimerN, KinterM, Vande Pol SB: Degradation of tyrosine phosphatase PTPN3 (PTPH1) by association with oncogenic human papillomavirus E6 proteins. J. Virol.81(5) , 2231–2239 (2007).
  • Spanos WC , HooverA, HarrisGF et al.: The PDZ binding motif of human papillomavirus type 16 E6 induces PTPN13 loss, which allows anchorage-independent growth and synergizes with ras for invasive growth.J. Virol.82(5) , 2493–2500 (2008).
  • Storrs CH , SilversteinSJ: PATJ, a tight junction-associated PDZ protein, is a novel degradation target of high-risk human papillomavirus E6 and the alternatively spliced isoform 18 E6.J. Virol.81(8) , 4080–4090 (2007).
  • Thomas M , MassimiP, NavarroC, BorgJP, BanksL: The hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteins.Oncogene24(41) , 6222–6230 (2005).
  • Chetkovich DM , ChenL, StockerTJ, NicollRA, BredtDS: Phosphorylation of the postsynaptic density-95 (PSD-95)/discs large/zona occludens-1 binding site of stargazin regulates binding to PSD-95 and synaptic targeting of AMPA receptors.J. Neurosci.22(14) , 5791–5796 (2002).
  • Sonoda T , MochizukiC, YamashitaT et al.: Binding of glutamate receptor δ2 to its scaffold protein, Delphilin, is regulated by PKA.Biochem. Biophys. Res. Commun.350(3) , 748–752 (2006).
  • Kuhne C , GardiolD, GuarnacciaC, AmenitschH, BanksL: Differential regulation of human papillomavirus E6 by protein kinase A: conditional degradation of human discs large protein by oncogenic E6.Oncogene19(51) , 5884–5891 (2000).
  • Narayan N , MassimiP, BanksL: CDK phosphorylation of the discs large tumour suppressor controls its localisation and stability.J. Cell Sci.122(Pt 1) , 65–74 (2009).
  • Nagasaka K , PimD, MassimiP et al.: The cell polarity regulator hScrib controls ERK activation through a KIM site-dependent interaction.Oncogene29(38) , 5311–5321 (2010).
  • Albertson R , DoeCQ: Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry.Nat. Cell Biol.5(2) , 166–170 (2003).
  • Jackson D , HossainMJ, HickmanD, PerezDR, LambRA: A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity.Proc. Natl Acad. Sci. USA105(11) , 4381–4386 (2008).
  • Wigerius M , MelikW, ElvangA, JohanssonM: Rac1 and Scribble are targets for the arrest of neurite outgrowth by TBE virus NS5.Mol. Cell. Neurosci.44(3) , 260–271 (2010).
  • Thomas M , KranjecC, NagasakaK, MatlashewskiG, BanksL: Analysis of the PDZ binding specificities of influenza A virus NS1 proteins.Virol. J.8 , 25 (2011).
  • Wu M , Pastor-ParejaJC, XuT: Interaction between RasV12 and scribbled clones induces tumour growth and invasion.Nature463(7280) , 545–548 (2010).
  • Li S , LabrecqueS, GauzziMC et al.: The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak–STAT activation by interferon-α.Oncogene18(42) , 5727–5737 (1999).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.