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Future Virology Volume 8, 2013 - Issue 9
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Research Article

Is IL-17 an Accomplice Contributing to Salivary Gland Damage During CMV Infection?

Ling-ling Liu1 Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan430030, ChinaView further author information
,
Xu-fang Li1 Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan430030, ChinaView further author information
,
Wen-qing Qin1 Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan430030, ChinaView further author information
,
Xing-lou Liu1 Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan430030, ChinaView further author information
,
Ge Li1 Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan430030, ChinaView further author information
,
Sai-nan Shu1 Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan430030, ChinaView further author information
&
Feng Fang1 Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan430030, ChinaCorrespondence[email protected]
View further author information
 show all
Pages 861-869 | Published online: 27 Aug 2013

References

  • Britt W . Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease. Curr. Top. Microbiol. Immunol.325 , 417–470 (2008).
  • Campbell AE , CavanaughVJ, SlaterJS. The salivary glands as a privileged site of cytomegalovirus immune evasion and persistence. Med. Microbiol. Immunol.197(2) , 205–213 (2008).
  • Snyder CM , LoewendorfA, BonnettEL, CroftM, BenedictCA, HillAB. CD4+ T cell help has an epitope-dependent impact on CD8+ T cell memory inflation during murine cytomegalovirus infection. J. Immunol.183(6) , 3932–3941 (2009).
  • Cavanaugh VJ , DengY, BirkenbachMP, SlaterJS, CampbellAE. Vigorous innate and virus-specific cytotoxic T-lymphocyte responses to murine cytomegalovirus in the submaxillary salivary gland. J. Virol.77(3) , 1703–1717 (2003).
  • Lucin P , PavicI, PolicB, JonjicS, KoszinowskiUH. Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands. J. Virol.66(4) , 1977–1984 (1992).
  • Hudson JB . The murine cytomegalovirus as a model for the study of viral pathofenesis and persistent infections. Arch. Virol.62 , 1–29 (1979).
  • Kelsey DK , OlsenGA, OverallJC Jr, Glasgow LA. Alteration of host defense mechanisms by murine cytomegalovirus infection. Infect. Immun.18(3) , 754–760 (1977).
  • Chang SH , DongC. Signaling of interleukin-17 family cytokines in immunity and inflammation. Cell. Signal.23(7) , 1069–1075 (2010).
  • van de Veerdonk FL , GresnigtMS, KullbergBJ, van der Meer JW, Joosten LA, Netea MG. Th17 responses and host defense against microorganisms: an overview. BMB Rep.42(12) , 776–787 (2009).
  • Li YN , LiuXL, HuangF, ZhouH, HuangYJ, FangF. CD4+CD25+ regulatory T cells suppress the immune responses of mouse embryo fibroblasts to murine cytomegalovirus infection. Immunol. Lett.131(2) , 131–138 (2010).
  • Xie Y , ChenR, ZhangX et al. The role of Th17 cells and regulatory T cells in coxsackievirus B3-induced myocarditis. Virology 421(1) , 78–84 (2011).
  • Wang DD , ZhaoYF, WangGY et al. IL-17 potentiates neuronal injury induced by oxygen-glucose deprivation and affects neuronal IL-17 receptor expression. J. Neuroimmunol. 212(1–2) , 17–25 (2009).
  • Pilgrim MJ , KasmanL, GrewalJ et al. A focused salivary gland infection with attenuated MCMV: an animal model with prevention of pathology associated with systemic MCMV infection. Exp. Mol. Pathol. 82(3) , 269–279 (2007).
  • Balanescu P , LadaruA, VoiosuT, NicolauA, EneM, BalanescuE. Th17 and IL-17 immunity in chronic hepatitis C infection. Rom. J. Intern. Med.50(1) , 13–18 (2012).
  • Yue FY , MerchantA, KovacsCM, LoutfyM, PersadD, OstrowskiMA. Virus-specific interleukin-17-producing CD4+ T cells are detectable in early human immunodeficiency virus type 1 infection. J. Virol.82(13) , 6767–6771 (2008).
  • Suryawanshi A , Veiga-PargaT, RajasagiNK et al. Role of IL-17 and Th17 cells in herpes simplex virus-induced corneal immunopathology. J. Immunol. 187(4) , 1919–1930 (2011).
  • Yang B , WangY, ZhaoC et al. Increased Th17 cells and interleukin-17 contribute to immune activation and disease aggravation in patients with chronic hepatitis B virus infection. Immunol. Lett. 149(1–2) , 41–49 (2012).
  • Smith CB , WeiLS, GriffithsM. Mouse cytomegalovirus is infectious for rats and alters lymphocyte subsets and spleen cell proliferation. Arch. Virol.90(3–4) , 313–323 (1986).
  • Calcedo R , VandenbergheLH, RoyS, SomanathanS, WangL, WilsonJM. Host immune responses to chronic adenovirus infections in human and nonhuman primates. J. Virol.83(6) , 2623–2631 (2009).
  • Kasman LM , LondonLL, LondonSD, PilgrimMJ. A mouse model linking viral hepatitis and salivary gland dysfunction. Oral Dis.15(8) , 587–595 (2009).
  • Jonjic S , MutterW, WeilandF, ReddehaseMJ, KoszinowskiUH. Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes. J. Exp. Med.169(4) , 1199–1212 (1989).
  • Jonjic S , PavicI, LucinP, RukavinaD, KoszinowskiUH. Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes. J. Virol.64(11) , 5457–5464 (1990).
  • Wilke CM , BishopK, FoxD, ZouW. Deciphering the role of Th17 cells in human disease. Trends Immunol.32(12) , 603–611 (2011).
  • Sun HQ , ZhangJY, ZhangH, ZouZS, WangFS, JiaJH. Increased Th17 cells contribute to disease progression in patients with HBV-associated liver cirrhosis. J. Viral Hepat.19(6) , 396–403 (2012).
  • Arens R , WangP, SidneyJ et al. Cutting edge: murine cytomegalovirus induces a polyfunctional CD4 T cell response. J. Immunol. 180(10) , 6472–6476 (2008).
  • Zhao JQ , ChenLZ, QiuJ et al. The role of interleukin-17 in murine cytomegalovirus interstitial pneumonia in mice with skin transplants. Transpl. Int. 24(8) , 845–855 (2011).
  • Hou W , KangHS, KimBS. Th17 cells enhance viral persistence and inhibit T cell cytotoxicity in a model of chronic virus infection. J. Exp. Med.206(2) , 313–328 (2009).
  • Wiehler S , ProudD. Interleukin-17A modulates human airway epithelial responses to human rhinovirus infection. Am. J. Physiol.293(2) , L505–L515 (2007).
  • Korn T , BettelliE, OukkaM, KuchrooVK. IL-17 and Th17 cells. Ann. Rev. Immunol.27 , 485–517 (2009).
  • Spriggs MK . Interleukin-17 and its receptor. J. Clin. Immunol.17(5) , 366–369 (1997).
  • Mieliauskaite D , DumalakieneI, RugieneR, MackiewiczZ. Expression of IL-17, IL-23 and their receptors in minor salivary glands of patients with primary Sjögren‘s sydrome. Clin. Dev. Immunol.2012 , 187258(2012).
  • Dardalhon V , KornT, KuchrooVK, AndersonAC. Role of Th1 and Th17 cells in organ-specific autoimmunity. J. Autoimmun.31(3) , 252–256 (2008).
  • Ouyang W , KollsJK, ZhengY. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity28(4) , 454–467 (2008).
  • Gaffen SL . An overview of IL-17 function and signaling. Cytokine43(3) , 402–407 (2008).

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