Liver transplantation in the management of perihilar cholangiocarcinoma

References

• Khan SA , DavidsonBR, GoldinRDet al. Guidelines for the diagnosis and treatment of cholangiocarcinoma: an update. Gut61(12), 1657–1669 (2012).
   PubMed Web of Science ®Google Scholar
• Olnes MJ , ErlichR. A review and update on cholangiocarcinoma. Oncology66(3), 167–179 (2004).
   PubMed Web of Science ®Google Scholar
• Burak K , AnguloP, PashaTM, EganK, PetzJ, LindorKD. Incidence and risk factors for cholangiocarcinoma in primary sclerosing cholangitis. Am. J. Gastroenterol.99(3), 523–526 (2004).
   PubMed Web of Science ®Google Scholar
• Rizvi S , GoresGJ. Pathogenesis, diagnosis, and management of cholangiocarcinoma. Gastroenterology145(6), 1215–1229 (2013).
   PubMed Web of Science ®Google Scholar
• Everhart JE , RuhlCE. Burden of digestive diseases in the United States part III: liver, biliary tract, and pancreas. Gastroenterology136(4), 1134–1144 (2009).
   PubMed Web of Science ®Google Scholar
• Blechacz B , KomutaM, RoskamsT, GoresGJ. Clinical diagnosis and staging of cholangiocarcinoma. Nat. Rev. Gastroenterol. Hepatol.8(9), 512–522 (2011).
   PubMed Web of Science ®Google Scholar
• Deoliveira ML , CunninghamSC, CameronJLet al. Cholangiocarcinoma: thirty-one-year experience with 564 patients at a single institution. Ann. Surg.245(5), 755–762 (2007).
   PubMed Web of Science ®Google Scholar
• Razumilava N , GoresGJ. Classification, diagnosis, and management of cholangiocarcinoma. Clin. Gastroenterol. Hepatol.11(1), 13–21, e11; quiz e13–e14 (2013).
   PubMed Web of Science ®Google Scholar
• Jarnagin WR . Cholangiocarcinoma of the extrahepatic bile ducts. Semin. Surg. Oncol.19(2), 156–176 (2000).
   PubMedGoogle Scholar
• Rea DJ , Munoz-JuarezM, FarnellMBet al. Major hepatic resection for hilar cholangiocarcinoma: analysis of 46 patients. Arch. Surg.139(5), 514–523, discussion 523–515 (2004).
   PubMedGoogle Scholar
• Petrowsky H , HongJC. Current surgical management of hilar and intrahepatic cholangiocarcinoma: the role of resection and orthotopic liver transplantation. Transplant. Proc.41(10), 4023–4035 (2009).
   PubMed Web of Science ®Google Scholar
• Ito F , ChoCS, RikkersLF, WeberSM. Hilar cholangiocarcinoma: current management. Ann. Surg.250(2), 210–218 (2009).
   PubMed Web of Science ®Google Scholar
• Lee SY , CherquiD. Operative management of cholangiocarcinoma. Semin. Liver Dis.33(3), 248–261 (2013).
   PubMed Web of Science ®Google Scholar
• Farley DR , WeaverAL, NagorneyDM. ‘Natural history’ of unresected cholangiocarcinoma: patient outcome after noncurative intervention. Mayo Clin. Proc.70(5), 425–429 (1995).
   PubMed Web of Science ®Google Scholar
• Kondo S , HiranoS, AmboYet al. Forty consecutive resections of hilar cholangiocarcinoma with no postoperative mortality and no positive ductal margins: results of a prospective study. Ann. Surg.240(1), 95–101 (2004).
   PubMed Web of Science ®Google Scholar
• Pichlmayr R , WeimannA, KlempnauerJet al. Surgical treatment in proximal bile duct cancer. A single-center experience. Ann. Surg.224(5), 628–638 (1996).
   PubMed Web of Science ®Google Scholar
• Kosuge T , YamamotoJ, ShimadaK, YamasakiS, MakuuchiM. Improved surgical results for hilar cholangiocarcinoma with procedures including major hepatic resection. Ann. Surg.230(5), 663–671 (1999).
   PubMed Web of Science ®Google Scholar
• Iwatsuki S , TodoS, MarshJWet al. Treatment of hilar cholangiocarcinoma (klatskin tumors) with hepatic resection or transplantation. J. Am. Coll. Surg.187(4), 358–364 (1998).
   PubMed Web of Science ®Google Scholar
• Jang JY , KimSW, ParkDJet al. Actual long-term outcome of extrahepatic bile duct cancer after surgical resection. Ann. Surg.241(1), 77–84 (2005).
   PubMed Web of Science ®Google Scholar
• Todoroki T , KawamotoT, KoikeNet al. Radical resection of hilar bile duct carcinoma and predictors of survival. Br. J. Surg.87(3), 306–313 (2000).
   PubMed Web of Science ®Google Scholar
• Jarnagin WR , FongY, DematteoRPet al. Staging, resectability, and outcome in 225 patients with hilar cholangiocarcinoma. Ann. Surg.234(4), 507–517, discussion 517–509 (2001).
   PubMed Web of Science ®Google Scholar
• Washburn WK , LewisWD, JenkinsRL. Aggressive surgical resection for cholangiocarcinoma. Arch. Surg.130(3), 270–276 (1995).
   PubMedGoogle Scholar
• Silva MA , TekinK, AytekinF, BramhallSR, BuckelsJA, MirzaDF. Surgery for hilar cholangiocarcinoma: a 10 year experience of a tertiary referral centre in the UK. Eur. J. Surg. Oncol.31(5), 533–539 (2005).
   PubMed Web of Science ®Google Scholar
• Li H , QinY, CuiY, ChenH, HaoX, LiQ. Analysis of the surgical outcome and prognostic factors for hilar cholangiocarcinoma: a Chinese experience. Dig. Surg.28(3), 226–231 (2011).
   PubMed Web of Science ®Google Scholar
• Saxena A , ChuaTC, ChuFC, MorrisDL. Improved outcomes after aggressive surgical resection of hilar cholangiocarcinoma: a critical analysis of recurrence and survival. Am. J. Surg.202(3), 310–320 (2011).
   PubMed Web of Science ®Google Scholar
• Regimbeau JM , FuksD, Le TreutYPet al. Surgery for hilar cholangiocarcinoma: a multi-institutional update on practice and outcome by the AFC-HC Study Group. J. Gastrointest. Surg.15(3), 480–488 (2011).
   PubMed Web of Science ®Google Scholar
• Meyer CG , PennI, JamesL. Liver transplantation for cholangiocarcinoma: results in 207 patients. Transplantation69(8), 1633–1637 (2000).
   PubMed Web of Science ®Google Scholar
• Brandsaeter B , IsoniemiH, BroomeUet al. Liver transplantation for primary sclerosing cholangitis; predictors and consequences of hepatobiliary malignancy. J. Hepatol.40(5), 815–822 (2004).
   PubMed Web of Science ®Google Scholar
• Robles R , FiguerasJ, TurrionVSet al. Spanish experience in liver transplantation for hilar and peripheral cholangiocarcinoma. Ann. Surg.239(2), 265–271 (2004).
   PubMed Web of Science ®Google Scholar
• Ghali P , MarottaPJ, YoshidaEMet al. Liver transplantation for incidental cholangiocarcinoma: analysis of the canadian experience. Liver Transpl.11(11), 1412–1416 (2005).
   PubMed Web of Science ®Google Scholar
• Alessiani M , TzakisA, TodoS, DemetrisAJ, FungJJ, StarzlTE. Assessment of five-year experience with abdominal organ cluster transplantation. J. Am. Coll. Surg.180(1), 1–9 (1995).
   PubMed Web of Science ®Google Scholar
• Cosgrove ND , Al-OsaimiAM, SanoffHKet al. Photodynamic therapy provides local control of cholangiocarcinoma in patients awaiting liver transplantation. Am. J. Transplant.14(2), 466–471 (2014).
   PubMed Web of Science ®Google Scholar
• Shimoda M , FarmerDG, ColquhounSDet al. Liver transplantation for cholangiocellular carcinoma: analysis of a single-center experience and review of the literature. Liver Transpl.7(12), 1023–1033 (2001).
   PubMed Web of Science ®Google Scholar
• Foo ML , GundersonLL, BenderCE, BuskirkSJ. External radiation therapy and transcatheter iridium in the treatment of extrahepatic bile duct carcinoma. Int. J. Radiat. Oncol. Biol. Phys.39(4), 929–935 (1997).
   PubMed Web of Science ®Google Scholar
• Alden ME , MohiuddinM. The impact of radiation dose in combined external beam and intraluminal ir-192 brachytherapy for bile duct cancer. Int. J. Radiat. Oncol. Biol. Phys.28(4), 945–951 (1994).
   PubMed Web of Science ®Google Scholar
• Sudan D , DerooverA, ChinnakotlaSet al. Radiochemotherapy and transplantation allow long-term survival for nonresectable hilar cholangiocarcinoma. Am. J. Transplant.2(8), 774–779 (2002).
   PubMed Web of Science ®Google Scholar
• Sio TT , MartensonJA, Jr., HaddockMGet al. Outcome of transplant-fallout patients with unresectable cholangiocarcinoma. Am. J. Clin. Oncol., (2014).
   PubMed Web of Science ®Google Scholar
• Darwish Murad S , KimWR, TherneauTet al. Predictors of pretransplant dropout and posttransplant recurrence in patients with perihilar cholangiocarcinoma. Hepatology56(3), 972–981 (2012).
   PubMed Web of Science ®Google Scholar
• Rea DJ , HeimbachJK, RosenCBet al. Liver transplantation with neoadjuvant chemoradiation is more effective than resection for hilar cholangiocarcinoma. Ann. Surg.242(3), 451–458, discussion 458–461 (2005).
   PubMed Web of Science ®Google Scholar
• Rosen CB , HeimbachJK, GoresGJ. Liver transplantation for cholangiocarcinoma. Transpl. Int.23(7), 692–697 (2010).
   PubMed Web of Science ®Google Scholar
• Sirica AE , GoresGJ. Desmoplastic stroma and cholangiocarcinoma: clinical implications and therapeutic targeting. Hepatology59(6), 2397–2402 (2014).
   PubMed Web of Science ®Google Scholar
• Blechacz BR , SanchezW, GoresGJ. A conceptual proposal for staging ductal cholangiocarcinoma. Curr. Opin. Gastroenterol.25(3), 238–239 (2009).
   PubMed Web of Science ®Google Scholar
• Blechacz B , GoresGJ. Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment. Hepatology48(1), 308–321 (2008).
   PubMed Web of Science ®Google Scholar
• Rizvi S , GoresGJ. Current diagnostic and management options in perihilar cholangiocarcinoma. Digestion89(3), 216–224 (2014).
   PubMed Web of Science ®Google Scholar
• Levy C , LympJ, AnguloP, GoresGJ, LarussoN, LindorKD. The value of serum CA 19–9 in predicting cholangiocarcinomas in patients with primary sclerosing cholangitis. Dig. Dis. Sci.50(9), 1734–1740 (2005).
   PubMed Web of Science ®Google Scholar
• Sinakos E , SaengerAK, KeachJ, KimWR, LindorKD. Many patients with primary sclerosing cholangitis and increased serum levels of carbohydrate antigen 19–9 do not have cholangiocarcinoma. Clin. Gastroenterol. Hepatol.9(5), 434–439, e431 (2011).
   PubMed Web of Science ®Google Scholar
• Patel AH , HarnoisDM, KleeGG, LarussoNF, GoresGJ. The utility of ca 19–9 in the diagnoses of cholangiocarcinoma in patients without primary sclerosing cholangitis. Am. J. Gastroenterol.95(1), 204–207 (2000).
   PubMed Web of Science ®Google Scholar
• Juntermanns B , RadunzS, HeuerMet al. Tumor markers as a diagnostic key for hilar cholangiocarcinoma. Eur. J. Med. Res.15(8), 357–361 (2010).
   PubMed Web of Science ®Google Scholar
• Ruys AT , Van BeemBE, EngelbrechtMR, BipatS, StokerJ, Van GulikTM. Radiological staging in patients with hilar cholangiocarcinoma: a systematic review and meta-analysis. Br. J. Radiol.85(1017), 1255–1262 (2012).
   PubMed Web of Science ®Google Scholar
• Lopera JE , SotoJA, MuneraF. Malignant hilar and perihilar biliary obstruction: use of MR cholangiography to define the extent of biliary ductal involvement and plan percutaneous interventions. Radiology220(1), 90–96 (2001).
   PubMed Web of Science ®Google Scholar
• Manfredi R , BarbaroB, MasselliG, VecchioliA, MaranoP. Magnetic resonance imaging of cholangiocarcinoma. Semin. Liver Dis.24(2), 155–164 (2004).
   PubMed Web of Science ®Google Scholar
• Masselli G , ManfrediR, VecchioliA, GualdiG. MR imaging and MR cholangiopancreatography in the preoperative evaluation of hilar cholangiocarcinoma: correlation with surgical and pathologic findings. Eur. Radiol.18(10), 2213–2221 (2008).
   PubMed Web of Science ®Google Scholar
• Vogl TJ , SchwarzWO, HellerMet al. Staging of klatskin tumours (hilar cholangiocarcinomas): comparison of MR cholangiography, MR imaging, and endoscopic retrograde cholangiography. Eur. Radiol.16(10), 2317–2325 (2006).
   PubMed Web of Science ®Google Scholar
• Barr Fritcher EG , KippBR, SlezakJMet al. Correlating routine cytology, quantitative nuclear morphometry by digital image analysis, and genetic alterations by fluorescence in situ hybridization to assess the sensitivity of cytology for detecting pancreatobiliary tract malignancy. Am. J. Clin. Pathol.128(2), 272–279 (2007).
   PubMed Web of Science ®Google Scholar
• Gonda TA , GlickMP, SethiAet al. Polysomy and p16 deletion by fluorescence in situ hybridization in the diagnosis of indeterminate biliary strictures. Gastrointest. Endosc.75(1), 74–79 (2012).
   PubMed Web of Science ®Google Scholar
• Kipp BR , StadheimLM, HallingSAet al. A comparison of routine cytology and fluorescence in situ hybridization for the detection of malignant bile duct strictures. Am. J. Gastroenterol.99(9), 1675–1681 (2004).
   PubMed Web of Science ®Google Scholar
• Dehaan RD , KippBR, SmyrkTC, AbrahamSC, RobertsLR, HallingKC. An assessment of chromosomal alterations detected by fluorescence in situ hybridization and p16 expression in sporadic and primary sclerosing cholangitis-associated cholangiocarcinomas. Hum. Pathol.38(3), 491–499 (2007).
   PubMed Web of Science ®Google Scholar
• Barr Fritcher EG , KippBR, VossJSet al. Primary sclerosing cholangitis patients with serial polysomy fluorescence in situ hybridization results are at increased risk of cholangiocarcinoma. Am. J. Gastroenterol.106(11), 2023–2028 (2011).
   PubMed Web of Science ®Google Scholar
• Barr Fritcher EG , VossJS, JenkinsSMet al. Primary sclerosing cholangitis with equivocal cytology: fluorescence in situ hybridization and serum CA 19–9 predict risk of malignancy. Cancer Cytopathol.121(12), 708–717 (2013).
   PubMed Web of Science ®Google Scholar
• Levy MJ , HeimbachJK, GoresGJ. Endoscopic ultrasound staging of cholangiocarcinoma. Curr. Opin. Gastroenterol.28(3), 244–252 (2012).
   PubMed Web of Science ®Google Scholar
• Mohamadnejad M , DewittJM, ShermanSet al. Role of EUS for preoperative evaluation of cholangiocarcinoma: a large single-center experience. Gastrointest. Endosc.73(1), 71–78 (2011).
   PubMed Web of Science ®Google Scholar
• Heimbach JK , SanchezW, RosenCB, GoresGJ. Trans-peritoneal fine needle aspiration biopsy of hilar cholangiocarcinoma is associated with disease dissemination. HPB (Oxford)13(5), 356–360 (2011).
   PubMed Web of Science ®Google Scholar
• Gleeson FC , RajanE, LevyMJet al. EUS-guided FNA of regional lymph nodes in patients with unresectable hilar cholangiocarcinoma. Gastrointest. Endosc.67(3), 438–443 (2008).
   PubMed Web of Science ®Google Scholar
• Rosen CB , Darwish MuradS, HeimbachJK, NybergSL, NagorneyDM, GoresGJ. Neoadjuvant therapy and liver transplantation for hilar cholangiocarcinoma: is pretreatment pathological confirmation of diagnosis necessary?J. Am. Coll. Surg.215(1), 31–38, discussion 38–40 (2012).
   PubMed Web of Science ®Google Scholar
• De Vreede I , SteersJL, BurchPAet al. Prolonged disease-free survival after orthotopic liver transplantation plus adjuvant chemoirradiation for cholangiocarcinoma. Liver Transpl.6(3), 309–316 (2000).
   PubMed Web of Science ®Google Scholar
• Negm AA , SchottA, VonbergRPet al. Routine bile collection for microbiological analysis during cholangiography and its impact on the management of cholangitis. Gastrointest. Endosc.72(2), 284–291 (2010).
   PubMed Web of Science ®Google Scholar
• Gores GJ , GishRG, SudanD, RosenCB. Model for end-stage liver disease (meld) exception for cholangiocarcinoma or biliary dysplasia. Liver Transpl.12(12 Suppl. 3), S95–97 (2006).
   PubMed Web of Science ®Google Scholar
• Darwish Murad S , KimWR, HarnoisDMet al. Efficacy of neoadjuvant chemoradiation, followed by liver transplantation, for perihilar cholangiocarcinoma at 12 US centers. Gastroenterology143(1), 88–98 e83; quiz e14 (2012).
   PubMed Web of Science ®Google Scholar
• Gores GJ , Darwish MuradS, HeimbachJK, RosenCB. Liver transplantation for perihilar cholangiocarcinoma. Dig. Dis.31(1), 126–129 (2013).
   PubMed Web of Science ®Google Scholar
• Mantel HT , RosenCB, HeimbachJKet al. Vascular complications after orthotopic liver transplantation after neoadjuvant therapy for hilar cholangiocarcinoma. Liver Transpl.13(10), 1372–1381 (2007).
   PubMed Web of Science ®Google Scholar
• Duignan S , MaguireD, RavichandCSet al. Neoadjuvant chemoradiotherapy followed by liver transplantation for unresectable cholangiocarcinoma: a single-centre national experience. HPB (Oxford)16(1), 91–98 (2014).
   PubMed Web of Science ®Google Scholar
• Friman S , FossA, IsoniemiHet al. Liver transplantation for cholangiocarcinoma: selection is essential for acceptable results. Scand. J. Gastroenterol.46(3), 370–375 (2011).
   PubMed Web of Science ®Google Scholar
• Hashimoto K , MillerCM. Liver transplantation for intrahepatic cholangiocarcinoma. J. Hepatobiliary Pancreat. Sci.22(2), 138–143 (2015).
   PubMed Web of Science ®Google Scholar
• Sapisochin G , De LopeCR, GastacaMet al. Intrahepatic cholangiocarcinoma or mixed hepatocellular-cholangiocarcinoma in patients undergoing liver transplantation: a Spanish matched cohort multicenter study. Ann. Surg.259(5), 944–952 (2014).
   PubMed Web of Science ®Google Scholar
• Sapisochin G , Rodriguez De LopeC, GastacaMet al. Very early’ intrahepatic cholangiocarcinoma in cirrhotic patients: should liver transplantation be reconsidered in these patients? Am. J. Transplant. 14(3), 660–667 (2014).
   PubMed Web of Science ®Google Scholar
• Hong JC , JonesCM, DuffyJPet al. Comparative analysis of resection and liver transplantation for intrahepatic and hilar cholangiocarcinoma: a 24-year experience in a single center. Arch. Surg.146(6), 683–689 (2011).
   PubMedGoogle Scholar
• Rana A , HongJC. Orthotopic liver transplantation in combination with neoadjuvant therapy: a new paradigm in the treatment of unresectable intrahepatic cholangiocarcinoma. Curr. Opin. Gastroenterol.28(3), 258–265 (2012).
   PubMed Web of Science ®Google Scholar
• Hong JC , PetrowskyH, KaldasFMet al. Predictive index for tumor recurrence after liver transplantation for locally advanced intrahepatic and hilar cholangiocarcinoma. J. Am. Coll. Surg.212(4), 514–520, discussion 520–511 (2011).
   PubMed Web of Science ®Google Scholar
• Kuhlmann JB , BlumHE. Locoregional therapy for cholangiocarcinoma. Curr. Opin. Gastroenterol.29(3), 324–328 (2013).
   PubMed Web of Science ®Google Scholar
• Welling TH , FengM, WanSet al. Neoadjuvant stereotactic body radiation therapy, capecitabine, and liver transplantation for unresectable hilar cholangiocarcinoma. Liver Transpl.20(1), 81–88 (2014).
   PubMed Web of Science ®Google Scholar