Advanced search
Publication Cover
Immunotherapy Volume 2, 2010 - Issue 6
Submit an article Journal homepage
34
Views
0
CrossRef citations to date
0
Altmetric
Review

Anti-αβ-T-Cell Receptor Antibodies in the Setting of Laryngeal Transplantation

Marshall Strome1 New York Head & Neck Institute, NY, USA
&
David G Lott2 Massachusetts General Hospital, Center for Laryngeal Surgery & Voice Rehabilitation, 1 Bowdoin Square, 11th Floor, Boston, MA02114, USA. Tel.: +1 617 726 1444 Fax: +1 617 726 [email protected]
Pages 835-845 | Published online: 22 Nov 2010

Bibliography

  • Moloney FJ , ComberH, O‘LorcainP, O‘KellyP, ConlonPJ, MurphyGM: A population-based study of skin cancer incidence and prevalence in renal transplant recipients.Br. J. Dermatol.154(3) , 498–504 (2006).
  • Tsuchida M , HiraharaH, MatsumotoY, AboT, EguchiS: Induction of specific unresponsiveness to cardiac allografts by short-term administration of anti-T cell receptor α β antibody.Transplantation57(2) , 256–262 (1994).
  • Dufter C , PostS, ThiesJ et al.: Short-term T cell receptor directed immunotherapy induces organ specific peripheral tolerance in a strongly incompatible rat model.Transplant. Immunol.2(4) , 278–284 (1994).
  • Heidecke CD , HancockWW, JakobsF et al.: α/β-TCR-directed therapy in rat cardiac allograft recipients: treatment prior to alloantigen exposure prevents sensitization and abrogates accelerated rejection.Transplantation59(1) , 78–84 (1995).
  • van den Bogaerde J , WhiteD, RoserB, KampingaJ, AspinallR: In vitro and in vivo effects of monoclonal antibodies against T cell subsets on allogeneic and xenogeneic responses in the rat.Transplantation50(6) , 915–920 (1990).
  • Yoshino S , SchlipkoterE, KinneR, HünigT, EmmrichF: Suppression and prevention of adjuvant arthritis in rats by a monoclonal antibody to the α/β T cell receptor.Eur. J. Immunol.20(12) , 2805–2808 (1990).
  • Jung S , KramerS, SchluesenerHJ, HünigT, ToykaK, HartungHP: Prevention and therapy of experimental autoimmune neuritis by an antibody against T cell receptors-α/β.J. Immunol.148(12) , 3768–3775 (1992).
  • Yoshino S , ClelandLG, MayrhoferG, BrownRR, SchwabJH: Prevention of chronic erosive streptococcal cell wall-induced arthritis in rats by treatment with a monoclonal antibody against the T cell antigen receptor α β.J. Immunol.146(12) , 4187–4189 (1991).
  • Bluestone JA , KhattriR, SciammasR, SperlingAI: TCR γδ cells: a specialized T-cell subset in the immune system.Annu. Rev. Cell Dev. Biol.11 , 307–353 (1995).
  • Hall BM : Cells mediating allograft rejection.Transplantation51(6) , 1141–1151 (1991).
  • Lin J , WeissA: T cell receptor signaling.J. Cell Sci.114(Pt 2) , 243–244 (2001).
  • Okkenhaug K , BilancioA, EmeryJL, VanhaesebroeckB: Phosphoinositide 3-kinase in T cell activation and survival.Biochem. Soc. Trans.32(Pt 2) , 332–335 (2004).
  • Davis MM : A new trigger for T cells.Cell110(3) , 285–287 (2002).
  • Coombs D , KalergisAM, NathensonSG, WofsyC, GoldsteinB: Activated TCRs remain marked for internalization after dissociation from pMHC.Nat. Immunol.10 , 926–931 (2002).
  • Okkenhaug K , VanhaesebroeckB: PI3K in lymphocyte development, differentiation and activation.Nat. Rev. Immunol.3(4) , 317–330 (2003).
  • Holtmeier W , KabelitzD: γδ T cells link innate and adaptive immune responses.Chem. Immunol. Allergy86 , 151–183 (2005).
  • Starzl TE , DemetrisAJ, MuraseN, IldstadS, RicordiC, TruccoM: Cell migration, chimerism, and graft acceptance.Lancet339(8809) , 1579–1582 (1992).
  • Starzl TE , ZinkernagelRM: Antigen localization and migration in immunity and tolerance.N. Engl. J. Med.339(26) , 1905–1913 (1998).
  • Murase N , StarzlTE, TanabeM et al.: Variable chimerism, graft-versus-host disease, and tolerance after different kinds of cell and whole organ transplantation from Lewis to brown Norway rats.Transplantation60(2) , 158–171 (1995).
  • Heidecke CD , ZantlN, MaierS et al.: Importance of T cells to accelerated rejection and acceptance of renal allografts in sensitized rat recipients.Transplantation66(10) , 1354–1361 (1998).
  • Hamano K , ItoH, ShirasawaB et al.: Anti-α β-T cell receptor monoclonal antibody induces tolerance without dominant infiltration by Th2 cells into grafts.Transplant Proc.30(7) , 3892 (1998).
  • Heidecke CD , HancockWW, WesterholtS: α/β-T cell receptor-directed therapy in rat allograft recipients. Long-term survival of cardiac allografts after pretreatment with R73 mAb is associated with upregulation of Th2-type cytokines.Transplantation61(6) , 948–956 (1996).
  • Heidecke CD , ZantlN, MaierS et al.: Induction of long-term rat renal allograft survival by pretransplant T cell receptor-α/β-targeted therapy.Transplantation61(2) , 336–339 (1996).
  • Henrickson M , ReidJ, BelletJS, SawchukSS, HirschR: Comparison of in vivo efficacy and mechanism of action of antimurine monoclonal antibodies directed against TCR α β (H57-597) and CD3 (145-2C11).Transplantation60(8) , 828–835 (1995).
  • Darby CR , MorrisPJ, WoodKJ: Evidence that long-term cardiac allograft survival induced by anti-CD4 monoclonal antibody does not require depletion of CD4+ T cells.Transplantation.54(3) , 483–490 (1992).
  • Gutstein NL , WofsyD: Administration of F(ab‘)2 fragments of monoclonal antibody to L3T4 inhibits humoral immunity in mice without depleting L3T4+ cells.J. Immunol.137(11) , 3414–3419 (1986).
  • Tanaka K , HancockWW, OsawaH et al.: Mechanism of action of anti-IL-2R monoclonal antibodies. ART-18 prolongs cardiac allograft survival in rats by elimination of IL-2R+ mononuclear cells.J. Immunol.143(9) , 2873–2879 (1989).
  • Siemionow M , OrtakT, IzyckiD et al.: Induction of tolerance in composite-tissue allografts.Transplantation74(9) , 1211–1217 (2002).
  • Black KS , HewittCW, FraserLA et al.: Composite tissue (limb) allografts in rats. II. Indefinite survival using low-dose cyclosporine.Transplantation39(4) , 365–368 (1985).
  • Brazelton TR , MorrisRE: Molecular mechanisms of action of new xenobiotic immunosuppressive drugs: tacrolimus (FK506), sirolimus (rapamycin), mycophenolate mofetil and leflunomide.Curr. Opin. Immunol.8(5) , 710–720 (1996).
  • Knight RJ , KurrleR, McClainJ et al.: Clinical evaluation of induction immunosuppression with a murine IgG2b monoclonal antibody (BMA 031) directed toward the human α/β-T cell receptor.Transplantation57(11) , 1581–1588 (1994).
  • Ozer K , IzyckiD, ZielinskiM, SiemionowM: Development of donor-specific chimerism and tolerance in composite tissue allografts under αβ-T-cell receptor monoclonal antibody and cyclosporine a treatment protocols.Microsurgery24(3) , 248–254 (2004).
  • Siemionow MZ , IzyckiDM, ZielinskiM: Donor-specific tolerance in fully major histocompatibility major histocompatibility complex mismatched limb allograft transplants under an Anti-αβ T-cell receptor monoclonal antibody and cyclosporine A protocol.Transplantation76(12) , 1662–1668 (2003).
  • Siemionow M , KlimczakA, UnalS, AgaogluG, CarnevaleK: Hematopoietic stem cell engraftment and seeding permits multi-lymphoid chimerism in vascularized bone marrow transplants.Am. J. Transpl.8(6) , 1163–1176 (2008).
  • Siemionow M , NasirS: Impact of donor bone marrow on survival of composite tissue allografts.Ann. Plast. Surg.60(4) , 455–462 (2008).
  • Prabhune KA , GorantlaVS, Perez-AbadiaG et al.: Composite tissue allotransplantation in chimeric hosts Part II. A clinically relevant protocol to induce tolerance in a rat model.Transplantation76(11) , 1548–1555 (2003).
  • Knott PD , DanO, StromeM: Induction with T-cell receptor antibody leads to long-term laryngeal allograft function.Am. J. Otol.29(6) , 398–402 (2008).
  • Akst LM , SiemionowM, DanO, IzyckiD, StromeM: Induction of tolerance in a rat model of laryngeal transplantation.Transplantation76(12) , 1763–1770 (2003).
  • Khariwala SS , DanO, LorenzRR, KlimczakA, SiemionowM, StromeM: Donor bone marrow in laryngeal transplantation: results of a rat study.Amer. J. Otol.29(4) , 242–249 (2008).
  • Khariwala SS , KnottPD, DanO, KlimczakA, SiemionowM, StromeM: Pulsed immunosuppression with everolimus and Anti-αβ T-cell receptor: laryngeal allograft preservation at six months.Ann. Otol. Rhinol. Laryngol.115(1) , 74–80 (2006).
  • Lott DG , KhariwalaS, DanO, StromeM: Ten-month laryngeal allograft survival using pulsed everolimus and Anti-αβ TCR antibody immunosuppression.Ann. Otol. Rhinol. Laryngol. (2010) (In Press).
  • Binder J , LehmannM, GraserE et al.: The effects of nondepleting CD4 targeted therapy in presensitized rat recipients of cardiac allografts.Transplantation61(5) , 804–811 (1996).
  • Hancock WW , SayeghMH, SablinskiT, KutJP, Kupiec-WeglinskiJW, MilfordEL: Blocking of mononuclear cell accumulation, cytokine production, and endothelial activation within rat cardiac allografts by CD4 monoclonal antibody therapy.Transplantation53(6) , 1276–1280 (1992).
  • Sablinski T , SayeghMH, KutJP, MilfordEL, TilneyNL, Kupiec-WeglinskiJW: Evidence that therapeutic strategies targeted at CD4+ cells modulate accelerated rejection of cardiac allografts in sensitized rats by different mechanisms.Transplantation54(2) , 292–296 (1992).
  • Hunig T , WallnyHJ, HartleyJK, LawetzkyA, TiefenthalerG: A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes.J. Exp. Med.169(1) , 73–86 (1989).
  • Cobbold SP , JayasuriyaA, NashA, ProsperoTD, WaldmanH: Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo.Nature312(5994) , 548–551 (1984).
  • Schwartz RH : A cell culture model for T lymphocyte clonal anergy.Science248(4961) , 1349–1356 (1990).
  • Rammensee HG , KroschewskiR, FrangoulisB: Clonal anergy induced in mature Vβ6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells.Nature339(6225) , 541–544 (1989).
  • Foster RD , LiuT: Orthotopic hindlimb transplantation in the mouse.J. Recon. Microsurg.19(1) , 49–52; discussion, 53–54 (2003).
  • Dallman MJ , LarsenCP, MorrisPJ: Cytokine gene transcription in vascularised organ grafts: analysis using semiquantitative polymerase chain reaction.J. Exp. Med.174(2) , 493–496 (1991).
  • Mottram PL , HanWR, PurcellLJ, McKenzieIFC, HancockWW: Increased expression of IL-4 and IL-10 and decreased expression of IL-2 and interferon-γ in long-surviving mouse heart allografts after brief CD4- monoclonal antibody therapy.Transplantation59(4) , 559–565 (1995).
  • Mosmann TR , MooreKW: The role of IL-10 in crossregulation of TH1 and Th2 responses.Immunol. Today12(3) , A49–A53 (1991).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.