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Research Article

Glycinated Fullerenes for Tamoxifen Intracellular Delivery With Improved Anticancer Activity and Pharmacokinetics

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Pages 1011-1023 | Received 26 Dec 2016, Accepted 15 Feb 2017, Published online: 25 Apr 2017

References

  • Cuenca AG Jiang H Hochwald SN Delano M Cance WG Grobmyer SR . Emerging implications of nanotechnology on cancer diagnostics and therapeutics . Cancer107 ( 3 ), 459 – 66 ( 2006 ).
  • Raza K Kumar M Kumar P et al. Topical delivery of aceclofenac: challenges and promises of novel drug delivery systems . Biomed. Res. Int.doi:https://doi.org/10.1155/2014/406731 ( 2014 ) ( Online ).
  • Madhwi Kumar R Kumar P et al. In vivo pharmacokinetic studies and intracellular delivery of methotrexate by means of glycine-tethered PLGA-based polymeric micelles . Int. J. Pharm.519 ( 1–2 ), 138 – 144 ( 2017 ).
  • Singh A Thotakura N Kumar R et al. PLGA-soya lecithin based micelles for enhanced delivery of methotrexate: cellular uptake, cytotoxic and pharmacokinetic evidences . Int. J. Biol. Macromol.95 , 750 – 756 ( 2017 ).
  • Shi J Votruba AR Farokhzad OC Langer R . Nanotechnology in drug delivery and tissue engineering: from discovery to applications . Nano Lett.10 ( 9 ), 3223 – 3230 ( 2010 ).
  • Pridgen EM Langer R Farokhzad OC . Biodegradable, polymeric nanoparticle delivery systems for cancer therapy . Nanomedicine2 ( 5 ), 669 – 680 ( 2007 ).
  • Riganti C Voena C Kopecka J et al. Liposome-encapsulated doxorubicin reverses drug resistance by inhibiting P-glycoprotein in human cancer cells . Mol. Pharm.8 ( 3 ), 683 – 700 ( 2011 ).
  • Raza K Kumar N Misra C et al. Dextran-PLGA-loaded docetaxel micelles with enhanced cytotoxicity and better pharmacokinetic profile . Int. J. Biol. Macromol.88 , 206 – 212 ( 2016 ).
  • Chen Y Yue Q De G et al. Inhibition of breast cancer metastasis by paclitaxel-loaded pH responsive poly(β-amino ester) copolymer micelles . Nanomedicine12 ( 2 ), 147 – 164 ( 2017 ).
  • Ahmad MZ Akhter S Anwar M Ahmad FJ . Assam Bora rice starch based biocompatible mucoadhesive microsphere for targeted delivery of 5-fluorouracil in colorectal cancer . Mol. Pharm.9 ( 11 ), 2986 – 2994 ( 2012 ).
  • Chin CF Yap SQ Li J et al. Ratiometric delivery of cisplatin and doxorubicin using tumour-targeting carbon-nanotubes entrapping platinum(IV) prodrugs . Chem. Sci.5 ( 6 ), 2265 ( 2014 ).
  • Raza K Kumar D Kiran C et al. Conjugation of docetaxel with multiwalled carbon nanotubes and codelivery with piperine: implications on pharmacokinetic profile and anticancer activity . Mol. Pharm.13 ( 7 ), 2423 – 2432 ( 2016 ).
  • Raza K Thotakura N Kumar P et al. C60-fullerenes for delivery of docetaxel to breast cancer cells: a promising approach for enhanced efficacy and better pharmacokinetic profile . Int. J. Pharm.495 ( 1 ), 551 – 559 ( 2015 ).
  • Shi J Zhang H Wang L et al. PEI-derivatized fullerene drug delivery using folate as a homing device targeting to tumor . Biomaterials34 ( 1 ), 251 – 261 ( 2013 ).
  • Zhu X Zhang Y Huang H Zhang H Hou L Zhang Z . Functionalized graphene oxide-based thermosensitive hydrogel for near-infrared chemo-photothermal therapy on tumor . J. Biomater. Appl.30 ( 8 ), 1230 – 1241 ( 2016 ).
  • Bianco A Kostarelos K Prato M Scrimin P Baltzer L . Applications of carbon nanotubes in drug delivery . This review comes from a themed issue on Model systems Edited . Curr. Opin. Chem. Biol.9 , 674 – 679 ( 2005 ).
  • Georgakilas V Perman J Tucek J Zboril R . Broad family of carbon nanoallotropes: classification, chemistry, and applications of fullerenes, carbon dots, nanotubes, graphene, nanodiamonds, and combined . Chem. Rev.115 ( 11 ), 4744 – 4822 ( 2015 ).
  • Partha R Conyers JL . Biomedical applications of functionalized fullerene-based nanomaterials . Int. J. Nanomedicine4 , 261 – 275 ( 2009 ).
  • Friedman SH Decamp DL Sijbesma RP Srdanov G Wudl F Kenyon'j GL . Inhibition of the HIV-1 protease by fullerene derivatives: model building studies and experimental verification . J. Am. Chem. Soc.115 , 6506 – 6509 ( 1993 ).
  • Mousavi SZ Nafisi S Maibach HI . Fullerene nanoparticle in dermatological and cosmetic applications . Nanomedicine13 ( 3 ), 1071 – 1087 ( 2016 ).
  • Mroz P Pawlak A Satti M et al. Functionalized fullerenes mediate photodynamic killing of cancer cells: type I versus type II photochemical mechanism . Free Radic. Biol. Med.43 ( 5 ), 711 – 719 ( 2007 ).
  • Foley S Crowley C Smaihi M et al. Cellular localisation of a water-soluble fullerene derivative . Biochem. Biophys. Res. Commun.294 ( 1 ), 116 – 119 ( 2002 ).
  • Yang J Wang K Driver J Yang J Barron AR . The use of fullerene substituted phenylalanine amino acid as a passport for peptides through cell membranes . Org. Biomol. Chem.5 ( 2 ), 260 – 266 ( 2006 ).
  • Kumar P Raza K Kaushik L Malik R . Role of colloidal drug delivery carriers in taxane-mediated chemotherapy: a review . Curr. Pharm. Des.22 ( 33 ), 5127 – 5143 ( 2016 ).
  • Maximov PY McDaniel RE Jordan VC . Tamoxifen: Pioneering Medicine in Breast Cancer . Springer Science & Business Media , Berlin, Germany ( 2013 ).
  • Shin SC Choi JS Li X . Enhanced bioavailability of tamoxifen after oral administration of tamoxifen with quercetin in rats . Int. J. Pharm.313 ( 1 ), 144 – 149 ( 2006 ).
  • Lipton A Harvey H Hamilton R . Venous thrombosis as a side effect of tamoxifen treatment . Cancer Treat. Rep.68 ( 6 ), 887 – 889 ( 1984 ).
  • Ulbricht J Jordan R Luxenhofer R . On the biodegradability of polyethylene glycol, polypeptoids and poly(2-oxazoline)s . Biomaterials35 ( 17 ), 4848 – 4861 ( 2014 ).
  • Nelson DJ Shagufta Kumar R . Characterization of a tamoxifen-tethered single-walled carbon nanotube conjugate by using NMR spectroscopy . Anal. Bioanal. Chem.404 ( 3 ), 771 – 776 ( 2012 ).
  • Reddy LH Vivek K Bakshi N Murthy RSR . Tamoxifen citrate loaded solid lipid nanoparticles (SLN™): preparation, characterization, in vitro drug release, and pharmacokinetic evaluation . Pharm. Dev. Technol.11 ( 2 ), 167 – 177 ( 2006 ).
  • Kratochwil NA Huber W Müller F Kansy M Gerber PR . Predicting plasma protein binding of drugs: a new approach . Biochem. Pharmacol.64 ( 9 ), 1355 – 1374 ( 2002 ).
  • Hu Z Guan W Wang W et al. Synthesis of amphiphilic amino acid C60 derivatives and their protective effect on hydrogen peroxide-induced apoptosis in rat pheochromocytoma cells . Carbon46 ( 1 ), 99 – 109 ( 2008 ).
  • Thakur CK Thotakura N Kumar R et al. Chitosan-modified PLGA polymeric nanocarriers with better delivery potential for tamoxifen . Int. J. Biol. Macromol.93 , 381 – 389 ( 2016 ).
  • Feng W Nie W He C et al. Effect of pH-responsive alginate/chitosan multilayers coating on delivery efficiency, cellular uptake and biodistribution of mesoporous silica nanoparticles based nanocarriers . ACS Appl. Mater. Interfaces6 ( 11 ), 8447 – 8460 ( 2014 ).
  • Bosi S Feruglio L Da Ros T et al. Hemolytic effects of water-soluble fullerene derivatives . J. Med. Chem.47 ( 27 ), 6711 – 6715 ( 2004 ).
  • Kolosnjaj J Szwarc H Moussa F . Toxicity studies of fullerenes and derivatives . In : Bio-Applications Of Nanoparticles . Landes Bioscience and Springer Science+Buisness Media , Berlin, Germany ( 2007 ).
  • Shi J Wang B Wang L et al. Fullerene (C60)-based tumor-targeting nanoparticles with ‘off-on’ state for enhanced treatment of cancer . J. Control. Release235 , 245 – 258 ( 2016 ).
  • Hu R Hilakivi-Clarke L Clarke R . Molecular mechanisms of tamoxifen-associated endometrial cancer (Review) . Oncol. Lett.9 ( 4 ), 1495 – 1501 ( 2015 ).
  • Gonzalez D Schmidt S Derendorf H . Importance of relating efficacy measures to unbound drug concentrations for anti-infective agents . Clin. Microbiol. Rev.26 ( 2 ), 274 – 288 ( 2013 ).

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