Anticancer Evaluation of Methotrexate and Curcumin-Coencapsulated Niosomes Against Colorectal Cancer Cell Lines

References

• Xi Y, Xu PJTO. Global colorectal cancer burden in 2020 and projections to 2040. Transl. Oncol. 14(10), 101174 (2021).
   PubMed Web of Science ®Google Scholar
• Chandran SP, Natarajan SB, Chandraseharan S, Shahimi MSBM. Nano drug delivery strategy of 5-fluorouracil for the treatment of colorectal cancer. J. Cancer Res. Pract. 4(2), 45–48 (2017).
   Google Scholar
• Rampado R, Crotti S, Caliceti P, Pucciarelli S, Agostini M. Nanovectors design for theranostic applications in colorectal cancer. J. Oncol. 2019, 2740923 (2019).
   PubMed Web of Science ®Google Scholar
• Mujokoro B, Madani F, Esnaashari SS, Khosravani M, Adabi M. Combination and co-delivery of methotrexate and curcumin: preparation and in vitro cytotoxic investigation on glioma cells. J. Pharm. Innov. 15(4), 617–626 (2019).
   Web of Science ®Google Scholar
• Alemi A, Reza JZ, Haghiralsadat F et al. Paclitaxel and curcumin coadministration in novel cationic PEGylated niosomal formulations exhibit enhanced synergistic antitumor efficacy. J. Nanobiotechnology 16(1), 28 (2018).
   PubMed Web of Science ®Google Scholar
• Reza BM, Tina SH, Narges B et al. Combination therapy in combating cancer. Oncotarget 8(23), 38022–38043 (2017).
   PubMedGoogle Scholar
• Thu HP, Nam NH, Duong L, Tham N, Quang B, Thi H. Targeting effect of folate on cancer cell through curcumin carrier nano-system. Int. J. Drug Deliv. 6(4), 351–358 (2014).
   Google Scholar
• Hagner N, Joerger M. Cancer chemotherapy: targeting folic acid synthesis. Cancer Manag. Res. 2, 293–301 (2010).
   PubMedGoogle Scholar
• Soe ZC, Poudel BK, Nguyen HT et al. Folate-targeted nanostructured chitosan/chondroitin sulfate complex carriers for enhanced delivery of bortezomib to colorectal cancer cells. Asian J. Pharm. Sci. 14(1), 40–51 (2019).
   PubMed Web of Science ®Google Scholar
• Chen H, Li S, Li B et al. Folate-modified gold nanoclusters as near-infrared fluorescent probes for tumor imaging and therapy. Nanoscale 4(19), 6050–6064 (2012).
   PubMed Web of Science ®Google Scholar
• Koźmiński P, Halik PK, Chesori R, Gniazdowska E. Overview of dual-acting drug methotrexate in different neurological diseases, autoimmune pathologies and cancers. Int. J. Mol. Sci. 21(10), 3483 (2020).
   PubMed Web of Science ®Google Scholar
• Nedelcu RI, Balaban M, Turcu G et al. Efficacy of methotrexate as anti-inflammatory and anti-proliferative drug in dermatology: three case reports. Exp. Ther. Med. 18(2), 905–910 (2019).
   PubMed Web of Science ®Google Scholar
• Bedoui Y, Guillot X, Sélambarom J et al. Methotrexate an old drug with new tricks. Int. J. Mol. Sci. 20(20), 5023 (2019).
   PubMed Web of Science ®Google Scholar
• Al-Quteimat OM, Al-Badaineh MA. Practical issues with high dose methotrexate therapy. Saudi. Pharm. J. 22(4), 385–387 (2014).
   PubMed Web of Science ®Google Scholar
• Nosrati H, Charmi J, Abhari F et al. Improved synergic therapeutic effects of chemoradiation therapy with the aid of a co-drug-loaded nano-radiosensitizer under conventional-dose x-ray irradiation. Biomater. Sci. 8(15), 4275–4286 (2020).
   PubMed Web of Science ®Google Scholar
• Liu Z, Huang P, Law S, Tian H, Leung W, Xu C. Preventive effect of curcumin against chemotherapy-induced side-effects. Front. Pharmacol. 9, 1374 (2018).
   PubMed Web of Science ®Google Scholar
• Tan BL, Norhaizan ME. Curcumin combination chemotherapy: the implication and efficacy in cancer. Molecules 24(14), 2527 (2019).
   PubMed Web of Science ®Google Scholar
• Agrawal DK, Mishra PK. Curcumin and its analogues: potential anticancer agents. Med. Res. Rev. 30(5), 818–860 (2010).
   PubMed Web of Science ®Google Scholar
• Yoozbashi M, Rashidzadeh H, Kermanian M et al. Magnetic nanostructured lipid carrier for dual triggered curcumin delivery: preparation, characterization and toxicity evaluation on isolated rat liver mitochondria. J. Biomater. Appl. doi: 10.1177/08853282211034625 (2021) ( Epub ahead of print).
   PubMed Web of Science ®Google Scholar
• Rashidzadeh H, Salimi M, Sadighian S, Rostamizadeh K, Ramazani A. In vivo antiplasmodial activity of curcumin-loaded nanostructured lipid carriers. Curr. Drug Deliv. 16(10), 923–930 (2019).
   PubMed Web of Science ®Google Scholar
• Rashidzadeh H, Rezaei SJT, Zamani S, Sarijloo E, Ramazani A. pH-sensitive curcumin conjugated micelles for tumor triggered drug delivery. J. Biomater. Sci. Polym. Ed. 32(3), 320–336 (2021).
   PubMed Web of Science ®Google Scholar
• Ag Seleci D, Seleci M, Walter J-G, Stahl F, Scheper T. Niosomes as nanoparticular drug carriers: fundamentals and recent applications. J. Nanomater. 2016, 7372306 (2016).
   Web of Science ®Google Scholar
• Mohamed HB, El-Shanawany SM, Hamad MA, Elsabahy M. Niosomes: a strategy toward prevention of clinically significant drug incompatibilities. Sci. Rep. 7(1), 1–14 (2017).
   PubMedGoogle Scholar
• Rathee J, Kanwar R, Kaushik D, Salunke DB, Mehta SKJaSS. Niosomes as efficient drug delivery modules for encapsulation of Toll-like receptor 7 agonists and IDO-inhibitor. Appl. Surf. Sci. 505, 144078 (2020).
   Web of Science ®Google Scholar
• Rudnik LaC, Farago PV, Manfron Budel J et al. Co-loaded curcumin and methotrexate nanocapsules enhance cytotoxicity against non-small-cell lung cancer cells. Molecules 25(8), 1913 (2020).
   PubMed Web of Science ®Google Scholar
• Curcio M, Cirillo G, Tucci P et al. Dextran-curcumin nanoparticles as a methotrexate delivery vehicle: a step forward in breast cancer combination therapy. Pharmaceuticals 13(1), 2 (2020).
   Web of Science ®Google Scholar
• Nematollahi MH, Pardakhty A, Torkzadeh-Mahanai M, Mehrabani M, Asadikaram G. Changes in physical and chemical properties of niosome membrane induced by cholesterol: a promising approach for niosome bilayer intervention. RSC Adv. 7(78), 49463–49472 (2017).
   Web of Science ®Google Scholar
• Gharbavi M, Johari B, Mousazadeh N et al. Hybrid of niosomes and bio-synthesized selenium nanoparticles as a novel approach in drug delivery for cancer treatment. Mol. Biol. Rep. 47(9), 6517–6529 (2020).
   PubMed Web of Science ®Google Scholar
• Naderinezhad S, Amoabediny G, Haghiralsadat F. Co-delivery of hydrophilic and hydrophobic anticancer drugs using biocompatible pH-sensitive lipid-based nano-carriers for multidrug-resistant cancers. RSC Adv. 7(48), 30008–30019 (2017).
   Web of Science ®Google Scholar
• Tavano L, Vivacqua M, Carito V, Muzzalupo R, Caroleo MC, Nicoletta F. Doxorubicin loaded magneto-niosomes for targeted drug delivery. Colloids. Surf. B Biointerfaces 102, 803–807 (2013).
   PubMed Web of Science ®Google Scholar
• Faghfoori MH, Nosrati H, Rezaeejam H et al. Anticancer effect of x-ray triggered methotrexate conjugated albumin coated bismuth sulfide nanoparticles on SW480 colon cancer cell line. Int. J. Pharm. 582, 119320 (2020).
   PubMed Web of Science ®Google Scholar
• Elmore S. Apoptosis: a review of programmed cell death. Toxicol. Pathol. 35(4), 495–516 (2007).
   PubMed Web of Science ®Google Scholar
• Zhao Z, Ukidve A, Krishnan V, Mitragotri S. nanocarriers. Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers. Adv. Drug Deliv.Rev. 143, 3–21 (2019).
   PubMed Web of Science ®Google Scholar
• Zhang X, Chen F, Ni J. A novel method to prepare magnetite chitosan microspheres conjugated with methotrexate (MTX) for the controlled release of MTX as a magnetic targeting drug delivery system. Drug Deliv. 16(5), 280–288 (2009).
   PubMed Web of Science ®Google Scholar
• Ekinci M, Ilem-Ozdemir D, Gundogdu E, Asikoglu M. Methotrexate loaded chitosan nanoparticles: preparation, radiolabeling and in vitro evaluation for breast cancer diagnosis. J. Drug Deliv. Sci. Technol. 30, 107–113 (2015).
   Web of Science ®Google Scholar
• Liu ZL, Tian DY, Li SP, Li XD, Lu TH. MTX/LDHs hybrids synthesized from reverse microemulsions: particle control and bioassay study. Int. J. Phar. 473(1–2), 414–425 (2014).
   PubMed Web of Science ®Google Scholar
• Chen X, Zou L-Q, Niu J, Liu W, Peng S-F, Liu C-M. The stability, sustained release and cellular antioxidant activity of curcumin nanoliposomes. Molecules 20(8), 14293–14311 (2015).
   PubMed Web of Science ®Google Scholar
• Singh PK, Wani K, Kaul-Ghanekar R, Prabhune A, Ogale S. From micron to nano-curcumin by sophorolipid co-processing: highly enhanced bioavailability, fluorescence, and anti-cancer efficacy. RSC Adv. 4(104), 60334–60341 (2014).
   Web of Science ®Google Scholar
• Ismail E, Sabry D, Mahdy H, Khalil MJJOSR. Synthesis and characterization of some ternary metal complexes of curcumin with 1, 10-phenanthroline and their anticancer applications. J. Sci. Res. 6(3), 509–519 (2014).
   Google Scholar
• Li Y, Chen X, Li W et al. Combination of anti-EGFR and anti-VEGF drugs for the treatment of previously treated metastatic colorectal cancer: a case report and literature review. Front. Oncol. 11, 1865 (2021).
   Web of Science ®Google Scholar
• Dhanasekaran S, Biswal BK, Sumantran VN, Verma RS. Augmented sensitivity to methotrexate by curcumin induced overexpression of folate receptor in KG-1 cells. Biochimie 95(8), 1567–1573 (2013).
   PubMed Web of Science ®Google Scholar
• Dhanasekaran S. Augmented cytotoxic effects of paclitaxel by curcumin induced overexpression of folate receptor-α for enhanced targeted drug delivery in HeLa cells. Phytomedicine 56, 279–285 (2019).
   PubMed Web of Science ®Google Scholar
• Deng Y, Zhang X, Shen H et al. Application of the nano-drug delivery system in treatment of cardiovascular diseases. Front. Bioeng. Biotechnol. 7, 489 (2020).
   PubMed Web of Science ®Google Scholar
• Patra JK, Das G, Fraceto LF et al. Nano based drug delivery systems: recent developments and future prospects. J. Nanobiotechnology 16(1), 71 (2018).
   PubMed Web of Science ®Google Scholar
• Lu B, Lv X, Le Y. Chitosan-modified PLGA nanoparticles for control-released drug delivery. Polymers 11(2), 304 (2019).
   PubMed Web of Science ®Google Scholar
• Xu Y-Q, Chen W-R, Tsosie JK et al. Niosome encapsulation of curcumin: characterization and cytotoxic effect on ovarian cancer cells. J. Nanomater. 2016, 6365295 (2016).
   Web of Science ®Google Scholar
• Vakilinezhad MA, Amini A, Dara T, Alipour S. Methotrexate and curcumin co-encapsulated PLGA nanoparticles as a potential breast cancer therapeutic system: in vitro and in vivo evaluation. Colloids. Surf. B Biointerfaces 184, 110515 (2019).
   PubMed Web of Science ®Google Scholar
• Ceren Ertekin Z, Sezgin Bayindir Z, Yuksel NJCDD. Stability studies on piroxicam encapsulated niosomes. Curr. Drug Deliv. 12(2), 192–199 (2015).
   PubMed Web of Science ®Google Scholar
• Golbaz R, Khoei S, Khoee S et al. Apoptosis pathway in the combined treatment of x-ray and 5-FU-loaded triblock copolymer-coated magnetic nanoparticles. Nanomedicine (Lond.) 15(23), 2255–2270 (2020).
   PubMed Web of Science ®Google Scholar
• Gharbavi M, Johari B, Rismani E, Mousazadeh N, Taromchi AH, Sharafi A. NANOG decoy oligodeoxynucleotide–encapsulated niosomes nanocarriers: a promising approach to suppress the metastatic properties of u87 human glioblastoma multiforme cells. ACS Chem. Neurosci. 11(24), 4499–4515 (2020).
   PubMed Web of Science ®Google Scholar
• Agarwal S, Mohamed MS, Raveendran S, Rochani AK, Maekawa T, Kumar DS. Formulation, characterization and evaluation of morusin loaded niosomes for potentiation of anticancer therapy. RSC Adv. 8(57), 32621–32636 (2018).
   PubMed Web of Science ®Google Scholar
• Zhu J, Zhao B, Xiong P et al. Curcumin induces autophagy via inhibition of yes-associated protein (YAP) in human colon cancer cells. Med. Sci. Monit. 24, 7035–7042 (2018).
   PubMed Web of Science ®Google Scholar
• Wu Q, Ou H, Shang Y, Zhang X, Wu J, Fan F. Nanoscale formulations: incorporating curcumin into combination strategies for the treatment of lung cancer. Drug Des. Devel. Ther. 15, 2695–2709 (2021).
   PubMed Web of Science ®Google Scholar
• Majidzadeh H, Araj-Khodaei M, Ghaffari M et al. The combination of berberine and methotrexate enhances anti-cancer effects in HeLa cancer cell line: a morphological study. Pharm. Sci. 27(4), 536–542 (2021).
   Google Scholar
• Albasher G, Alkahtane AA, Saud Alarifi DA et al. Methotrexate-induced apoptosis in human ovarian adenocarcinoma SKOV-3 cells via ROS-mediated bax/bcl-2-cyt-c release cascading. OncoTargets Ther. 12, 21–30 (2019).
   PubMed Web of Science ®Google Scholar
• Meng F, Yun Z, Yan G, Wang G, Lin CJPB. Engineering of anticancer drugs entrapped polymeric nanoparticles for the treatment of colorectal cancer therapy. Process Biochem. 111, 36–42 (2021).
   Web of Science ®Google Scholar
• Un RN, Barlas FB, Yavuz M, Phyto-niosomes:in vitro assessment of the novel nanovesicles containing marigold extract. Int. J. Polym. Mater. 64(17), 927–937 (2015).
   Web of Science ®Google Scholar
• Chen CC, Sureshbabul M, Chen HW et al. Curcumin suppresses metastasis via Sp-1, FAK inhibition, and E-cadherin upregulation in colorectal cancer. Evid. Based Complement. Alternat. Med. 2013, 541695 (2013).
   PubMed Web of Science ®Google Scholar