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Nanomedicine Volume 7, 2012 - Issue 1
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Editorial

Studying The In Vitro Behavior of Cationic Solid Lipid Nanoparticles as A Nonviral Vector

Eleonora Vighia Department of Pharmaceutical Sciences, University of Modena & Reggio Emilia, via Campi, 183, Modena, ItalyView further author information
&
Eliana Leob Department of Pharmaceutical Sciences, University of Modena & Reggio Emilia, via Campi, 183, Modena, Italy. [email protected]Correspondence[email protected]
View further author information
Pages 9-12 | Published online: 22 Dec 2011

References

  • McDonald D , IldikoB, ShawnWet al. Advancing nonviral gene delivery: lipid- and surfactant-based nanoparticle design strategies. Nanomedicine 5, 1103–1127 (2010).
  • Wissing SA , KayseO, MullerRH. Solid lipid nanoparticles for parenteral drug delivery. Adv. Drug Deliv. Rev.56, 1257–1272 (2004).
  • Blasi P , GiovagnoliS, SchoubbenA, RicciM, RossiC. Solid lipid nanoparticles for targeted brain drug delivery. Adv. Drug Deliv. Rev.59, 454–477 (2007).
  • Harms M , Müller-GoymannCC. Solid lipid nanoparticles for drug delivery. Drug Del. Sci. Tech.21, 89–99 (2011).
  • Gasco MR . Lipid nanoparticles: perspectives and challenges. Adv. Drug Deliv. Rev.59, 377–378 (2007).
  • Bondi ML , CraparoEF. Solid lipid nanoparticles for applications in gene therapy: a review of the state of the art. Expert Opin. Drug Deliv.7, 7–18 (2010).
  • Olbrich C , BakowskyU, LehrCM, MüllerRH, KneuerC. Cationic solid-lipid nanoparticles can efficiently bind and transfect plasmid DNA. J. Control. Release77, 345–355 (2001).
  • Vighi E , RuoziB, MontanariM, BattiniR, LeoE. Re-dispersible cationic solid lipid nanoparticles (SLNs) freeze-dried without cryoprotectors: characterization and ability to bind the pEGFP-plasmid. Eur. J. Pharm. Biopharm.67, 320–328 (2007).
  • Doktorovova S , ShegokarR, RakovskyEet al. Cationic solid lipid nanoparticles (cSLN): structure, stability and DNA binding capacity correlation studies. Int. J. Pharm. 420, 341–349 (2011).
  • Rudolph C , SchillingerU, OrtizAet al. Application of novel solid lipid nanoparticle (SLN)-gene vector formulations based on a dimeric HIV-1 TAT-peptide in vitro and in vivo. Pharm. Res. 21, 1662–1669 (2004).
  • Vighi E , RuoziB, MontanariM, BattiniR, LeoE. pDNA condensation capacity and in vitro gene delivery properties of cationic solid lipid nanoparticles. Int. J. Pharm.389, 254–261 (2010).
  • Yu W , LiuC, YeJ, ZouW, ZhangN, XuW. Novel cationic SLN containing a synthesized single-tailed lipid as a modifier for gene delivery. Nanotecnology20, 102–112 (2009).
  • del Pozo-Rodriguez A , PujalsS, DelgadoDet al. A proline-rich peptide improves cell transfection of solid lipid nanoparticle-based non viral-vectors. J. Control. Release 133, 52–59 (2009).
  • Morille M , PassiraniC, VonarbourgA, ClavreulA, BenoitJP. Progress in developing cationic vectors for non-viral systemic gene therapy against cancer. Biomaterials29, 3477–3496 (2008).
  • Li X , LinX, ZhengLet al. Effect of poly(ethylene glycol) stearate on the phase behavior of monocaprate/tween80/water system and characterization of poly(ethylene glycol) stearate-modified solid lipid nanoparticles. Colloid Surf. A Physicochem. Eng. Aspects 317, 352–359 (2007).
  • Yu W , LiuC, LiuY, ZhangN, XuW. Mannan-modified solid lipid nanoparticles for targeted gene delivery to alveolar macrophages. Pharm. Res.27, 1584–1596 (2010).
  • Delgado D , del Pozo-Rodríguez A, Solinís MA, Rodríguez-Gascón A. Understanding the mechanism of protamine in solid lipid nanoparticle-based lipofection: the importance of the entry pathway. Eur. J. Pharm. Biopharm.79, 495–502 (2011).
  • del Pozo-Rodriguez A , DelgadoD, SolinisMA, GasconAR, PedrezJL. Solid lipid nanoparticles: formulation factors affecting cell transfection capacity. Int. J. Pharm.339, 261–268 (2007).
  • Tiera MJ , ShiQ, WinnikFM, FernandesJC. Polycation-based gene therapy: current knowledge and new perspectives. Curr. Gene Ther.11, 288–306 (2011).
  • Choi SH , JinSE, LeeMKet al. Novel cationic solid lipid nanoparticles enhanced p53 gene transfer to lung cancer cells. Eur. J. Pharm. Biopharm. 68, 545–554 (2008).
  • Vighi E , MontanariM, RuoziB, TosiG, MagliA, LeoE. Nuclear localization of cationic solid lipid nanoparticles containing Protamine as transfection promoter. Eur. J. Pharm. Biopharm.76, 384–393 (2010).
  • Vighi E , LeoE, MontanariM, MucciA, HanuskovaM, IannuccelliV. Structural investigation and intracellular trafficking of a novel multicomposite cationic SLN platform as pDNA carrier. Ther. Deliv.2, 1419–1435 (2011).
  • Buse J , El-AneedA. Properties, engineering and applications of lipid-based nanoparticle drug-delivery systems: current research and advances. Nanomedicine5, 1237–1260 (2010).
  • Nimesh S , GuptaN, ChandraR. Strategies and advances in nanomedicine for targeted siRNA delivery. Nanomedicine (Lond.)6(4), 729–746 (2011).

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