References
- Xu G , RenGJ , XuXet al. Combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis . Food Chem. Toxicol.48 ( 1 ), 390 – 395 ( 2010 ).
- Bar-Sela G , EpelbaumR , SchafferM . Curcumin as an anticancer agent: review of the gap between basic and clinical applications . Curr. Med. Chem.17 ( 3 ), 190 – 197 ( 2010 ).
- Lonnerdal B , IyerS . Lactoferrin – molecular structure and biological function . Ann. Rev. Nutr.15 , 93 – 110 ( 1995 ).
- Valenti P , AntoniniG . Lactoferrin: an important host defence against microbial and viral attack . Cell. Mol. Life Sci.62 ( 22 ), 2576 – 2587 ( 2005 ).
- Kanwar JR , KanwarRK , SunXYet al. Molecular and biotechnological advances in milk proteins in relation to human health . Curr. Protein Peptide Sci.10 ( 4 ), 308 – 338 ( 2009 ).
- Burrow H , KanwarRK , KanwarJR . Antioxidant enzyme activities of iron-saturated bovine lactoferrin (Fe-bLf) in human gut epithelial cells under oxidative stress . Med. Chem.7 ( 3 ), 224 – 230 ( 2011 ).
- Gibbons JA , KanwarRK , KanwarJR . Lactoferrin and cancer in different cancer models . Front. Biosci. (Schol. Ed.)3 , 1080 – 1088 ( 2011 ).
- Bi BY , LefebvreAM , DusD , SpikG , MazurierJ . Effect of lactoferrin on proliferation and differentiation of the Jurkat human lymphoblastic T cell line . Arch. Immunol. Ther. Exp. (Warsz.)45 ( 4 ), 315 – 320 ( 1997 ).
- Ward PP , Mendoza-MenesesM , Mulac-JericevicBet al. Restricted spatiotemporal expression of lactoferrin during murine embryonic development . Endocrinology140 ( 4 ), 1852 – 1860 ( 1999 ).
- Baveye S , ElassE , FernigDG , BlanquartC , MazurierJ , LegrandD . Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex . Infect. Immun.68 ( 12 ), 6519 – 6525 ( 2000 ).
- Artym J . [Antitumor and chemopreventive activity of lactoferrin] . Postepy. Hig. Med. Dosw. (Online)60 , 352 – 369 ( 2006 ).
- Cornish J , NaotD . Lactoferrin as an effector molecule in the skeleton . Biometals23 ( 3 ), 425 – 430 ( 2010 ).
- Gonzalez-Chavez SA , Arevalo-GallegosS , Rascon-CruzQ . Lactoferrin: structure, function and applications . Int. J. Antimicrob. Agents33 ( 4 ), 301.e301 – e308 ( 2009 ).
- Tsuda H , KozuT , IinumaGet al. Cancer prevention by bovine lactoferrin: from animal studies to human trial . Biometals23 ( 3 ), 399 – 409 ( 2010 ).
- Jeffrey PD , BewleyMC , MacGillivrayRTA , MasonAB , WoodworthRC , BakerEN . Ligand-induced conformational change in transferrins: crystal structure of the open form of the N-terminal half-molecule of human transferrin . Biochemistry37 ( 40 ), 13978 – 13986 ( 1998 ).
- Recht L , TorresCO , SmithTW , RasoV , GriffinTW . Transferrin receptor in normal and neoplastic brain-tissue – implications for brain-tumor immunotherapy . J. Neurosurg.72 ( 6 ), 941 – 945 ( 1990 ).
- Takayama Y , TakahashiH , MizumachiK , TakezawaT . Low density lipoprotein receptor-related protein (LRP) is required for lactoferrin-enhanced collagen gel contractile activity of human fibroblasts . J. Biol. Chem.278 ( 24 ), 22112 – 22118 ( 2003 ).
- Kanwar JR , PalmanoKP , SunXYet al. ‘Iron-saturated’ lactoferrin is a potent natural adjuvant for augmenting cancer chemotherapy . Immunol. Cell Biol.86 ( 3 ), 277 – 288 ( 2008 ).
- Burrow H , KanwarRK , MahidharaG , KanwarJR . Effect of selenium-saturated bovine lactoferrin (Se-bLF) on antioxidant enzyme activities in human gut epithelial cells under oxidative stress . Anticancer Agents Med. Chem.11 ( 8 ), 762 – 771 ( 2011 ).
- Ma J , GuanR , ShenHet al. Comparison of anticancer activity between lactoferrin nanoliposome and lactoferrin in Caco-2 cells in vitro. Food Chem. Toxicol. 59 , 72 – 77 ( 2013 ).
- Kanwar JR , MahidharaG , KanwarRK . Recent advances in nanoneurology for drug delivery to the brain . Curr. Nanosci.5 ( 4 ), 441 – 448 ( 2009 ).
- Kanwar JR , MahidharaG , KanwarRK . Novel alginate-enclosed chitosan-calcium phosphate-loaded iron-saturated bovine lactoferrin nanocarriers for oral delivery in colon cancer therapy . Nanomedicine7 ( 10 ), 1521 – 1550 ( 2012 ).
- Mahidhara G , KanwarRK , KanwarJR . A novel nanoplatform for oral delivery of anti-cancer biomacromolecules . Int. J. Nanotechnol.9 , 942 – 960 ( 2012 ).
- Chen YL , LeeHP , ChanHY , SungLY , ChenHC , HuYC . Composite chondroitin-6-sulfate/dermatan sulfate/chitosan scaffolds for cartilage tissue engineering . Biomaterials28 ( 14 ), 2294 – 2305 ( 2007 ).
- Ma H , JiangQ , HanSet al. Multicellular tumor spheroids as an in vivo-like tumor model for three-dimensional imaging of chemotherapeutic and nano material cellular penetration . Mol. Imaging11 ( 6 ), 487 – 498 ( 2012 ).
- Monazzam A JR , BlomqvistC , CarlssonJ , LångströmB , BergströmM . Application of the multicellular tumour spheroid model to screen PET tracers for analysis of early response of chemotherapy in breast cancer . Breast Cancer Res.9 ( 4 ), 1 – 8 ( 2007 ).
- Rossomacha E , HoemannCD , ShiveMS . Simple methods for staining chitosan in biotechnological applications . J. Histotechnol1 ( 6 ), 31 – 36 ( 2004 ).
- Samarasinghe RM , KanwarRK , KumarK , KanwarJR . Antiarthritic and chondroprotective activity of Lakshadi Guggul in novel alginate-enclosed chitosan calcium phosphate nanocarriers . Nanomedicine (Lond.) doi:10.2217/nnm.13.219 (2014 ) (Epub ahead of print) .
- Baratchi S , KanwarRK , KanwarJR . Novel survivin mutant protects differentiated SK-N-SH human neuroblastoma cells from activated T-cell neurotoxicity . J. Neuroimmunol.233 ( 1–2 ), 18 – 28 ( 2011 ).
- Liao Y , LönnerdalB . miR-584 mediates post-transcriptional expression of lactoferrin receptor in Caco-2 cells and in mouse small intestine during the perinatal period . Int. J. Biochem. Cell Biol42 ( 8 ), 1363 – 1369 ( 2010 ).
- Liao YL , DuXG , LonnerdalB . miR-214 regulates lactoferrin expression and pro-apoptotic function in mammary epithelial cells . J. Nutr.140 ( 9 ), 1552 – 1556 ( 2010 ).
- Kanwar RK , GangulyNK , KumarL , RakeshJ , PanigrahiD , WaliaBNS . Calcium and protein-kinase-C play an important role in Campylobacter jejuni-induced changes in Na+ and Cl- transport in rat ileumin vitro. Biochim. Biophys. Acta1270 ( 2–3 ), 179 – 192 ( 1995 ).
- Chakravarty PK . Evaluation of serum zinc level under malignant condition and its possible implication on improving cell-mediated immunity during cancer progression . World J. Oncol.2 ( 1 ), 16 – 23 ( 2011 ).
- Chang JW , YehKY , ShenYCet al. Production of multiple cytokines and induction of cachexia in athymic nude mice by a new anaplastic thyroid carcinoma cell line . J. Endocrinol.179 ( 3 ), 387 – 394 ( 2003 ).
- Tartour E , FossiezF , JoyeuxIet al. Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice . Cancer Res.59 ( 15 ), 3698 – 3704 ( 1999 ).
- Palaniappan PRM , VijayasundaramV , PrabuSM . A study of the subchronic effects of arsenic exposure on the liver tissues of Labeo rohita using fourier transform infrared technique . Environ. Toxicol.26 ( 4 ), 338 – 344 ( 2011 ).
- Strickland DK , GoniasSL , ArgravesWS . Diverse roles for the LDL receptor family . Trends Endocrinol. Metab.13 ( 2 ), 66 – 74 ( 2002 ).
- Kanwar RK , KanwarJR . Immunomodulatory lactoferrin in the regulation of apoptosis modulatory proteins in cancer . Protein Peptide Lett.20 ( 4 ), 450 – 458 ( 2013 ).
- Hogquist KA , NettMA , UnanueER , ChaplinDD . Interleukin 1 is processed and released during apoptosis . Proc. Natl Acad. Sci. USA88 ( 19 ), 8485 – 8489 ( 1991 ).
- Scheller J CA , Schmidt-ArrasD , Rose-JohnS . The pro- and anti-inflammatory properties of the cytokine interleukin-6 . Biochim. Biophys. Acta1813 ( 5 ), 878 – 888 ( 2011 ).
- Kannan Y , YuJ , RaicesRMet al. IκBζ augments IL-12- and IL-18-mediated IFN-γ production in human NK cells . Blood117 ( 10 ), 2855 – 2863 ( 2011 ).
- Koyasu S , MoroK . Type 2 innate immune responses and the natural helper cell . Immunology132 ( 4 ), 475 – 481 ( 2011 ).
- Elliott KA , OsnaNA , ScofieldMA , KhanMM . Regulation of IL-13 production by histamine in cloned murine T helper type 2 cells . Int. Immunopharmacol.1 ( 11 ), 1923 – 1937 ( 2001 ).
- Morrissey PJ , GrabsteinKH , ReedSG , ConlonPJ . Granulocyte/macrophage colony stimulating factor . Int. Arch. Allergy Immunol.88 , 40 – 45 ( 1989 ).
- Haubner R , WesterHJ , ReuningUet al. Radiolabeled alpha(v)beta(3) integrin antagonists: a new class of tracers for tumor targeting . J. Nucl. Med.40 ( 6 ), 1061 – 1071 ( 1999 ).
- Noiri E , GoligorskyMS , WangGJet al. Biodistribution and clearance of 99mTc-labeled Arg-Gly-Asp (RGD) peptide in rats with ischemic acute renal failure . J. Am. Soc. Nephrol.7 ( 12 ), 2682 – 2688 ( 1996 ).
- Sivolapenko GB , SkarlosD , PectasidesDet al. Imaging of metastatic melanoma utilising a technetium-99m labeled RGD-containing synthetic peptide . Eur. J. Nucl. Med.25 ( 10 ), 1383 – 1389 ( 1998 ).
- Zhou L , WeiX , ChengL , TianJ , JiangJJ . CD133, one of the markers of cancer stem cells in Hep-2 cell line . Laryngoscope117 , 455 – 460 ( 2007 ).
- Ren F , ShengWQ , DuX . CD133: a cancer stem cells marker, is used in colorectal cancers . World J. Gastroenterol.19 ( 17 ), 2603 – 2611 ( 2013 ).
- Du L , WangH , HeL . CD44 is of functional importance for colorectal cancer stem cells . Clin. Cancer Res.14 ( 23 ), 7964 – 7967 ( 2008 ).
- Liu D SJ , ZhuJ , ZhouH , ZhangX , ZhangY . Expression and clinical significance of colorectal cancer stem cell marker EpCAMhigh/CD44+ in colorectal cancer . Oncol. Lett.7 ( 5 ), 1544 – 1548 ( 2014 ).
- Hirschhaeuser F , MenneH , DittfeldC , WestJ , Mueller-KlieserW , Kunz-SchughartLA . Multicellular tumor spheroids: an underestimated tool is catching up again . J. Biotechnol.148 ( 1 ), 3 – 15 ( 2010 ).
- Baldrick P . The safety of chitosan as a pharmaceutical excipient . Regulat. Toxicol. Pharmacol.56 ( 3 ), 290 – 299 ( 2010 ).
- Gades MD , SternJS . Chitosan supplementation and fat absorption in men and women . J. Am. Diet. Assoc.105 ( 1 ), 72 – 77 ( 2005 ).
- Tugcu-Demiroz F , AcarturkF , TakkaS , Konus-BoyunagaO . Evaluation of alginate based mesalazine tablets for intestinal drug delivery . Eur. J. Pharmaceut. Biopharmaceut.67 ( 2 ), 491 – 497 ( 2007 ).
- Grey A , BanovicT , ZhuQet al. The low-density lipoprotein receptor-related protein 1 is a mitogenic receptor for lactoferrin in osteoblastic cells . Mol. Endocrinol.18 ( 9 ), 2268 – 2278 ( 2004 ).
- Davis M , ClarkeS . Influence of microRNA on the maintenance of human iron metabolism . Nutrients5 ( 7 ), 2611 – 2628 ( 2013 ).
- Schaar DG , MedinaDJ , MooreDF , StrairRK , TingY . miR-320 targets transferrin receptor 1 (CD71) and inhibits cell proliferation . Exp. Hematol.37 ( 2 ), 245 – 255 ( 2009 ).
- Andolfo I , De FalcoL , AsciRet al. Regulation of divalent metal transporter 1 (DMT1) non-IRE isoform by the microRNA Let-7d in erythroid cells . Haematologica95 ( 8 ), 1244 – 1252 ( 2010 ).
- Li YJ , LinL , LiZGet al. Iron homeostasis regulates the activity of the microRNA pathway through poly(C)-binding protein 2 . Cell Metab.15 ( 6 ), 895 – 904 ( 2012 ).
- Camaschella C , StratiP . Recent advances in iron metabolism and related disorders . Intern. Emerg. Med.5 ( 5 ), 393 – 400 ( 2010 ).
- Castoldi M , SpasicMV , AltamuraSet al. The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice . J. Clin. Invest.121 ( 4 ), 1386 – 1396 ( 2011 ).
- Iino I , KikuchiH , MiyazakiSet al. Effect of miR-122 and its target gene cationic amino acid transporter 1 on colorectal liver metastasis . Cancer Sci.104 ( 5 ), 624 – 630 ( 2013 ).
- Shimamura M , YamamotoY , AshinoHet al. Bovine lactoferrin inhibits tumor-induced angiogenesis . Int. J. Cancer111 ( 1 ), 111 – 116 ( 2004 ).
- Kanwar JR , BergRW , YangYet al. Requirements for ICAM-1 immunogene therapy of lymphoma . Cancer Gene Ther.10 ( 6 ), 468 – 476 ( 2003 ).