Advanced search
Publication Cover
Pharmacogenomics Volume 11, 2010 - Issue 3
Submit an article Journal homepage
244
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Genome-Wide Association for Smoking Cessation Success: Participants in the Patch in Practice Trial of Nicotine Replacement

George R Uhl1 Molecular Neurobiology Branch, NIH-IRP (NIDA), Suite 3510, 333 Cassell Drive Baltimore, MD21224, USA.Correspondence[email protected]
View further author information
,
Tomas Drgon1 Molecular Neurobiology Branch, NIH-IRP (NIDA), Suite 3510, 333 Cassell Drive Baltimore, MD21224, USA.View further author information
,
Catherine Johnson1 Molecular Neurobiology Branch, NIH-IRP (NIDA), Suite 3510, 333 Cassell Drive Baltimore, MD21224, USA.View further author information
,
Donna Walther1 Molecular Neurobiology Branch, NIH-IRP (NIDA), Suite 3510, 333 Cassell Drive Baltimore, MD21224, USA.View further author information
,
Sean P David3 SRI International, Menlo Park, CA, USA;2 Center for Education in Family & Community Medicine, Stanford University School of Medicine, Stanford, CA, USAView further author information
,
Paul Aveyard4 Primary Care Clinical Sciences, University of Birmingham, Birmingham, UKView further author information
,
Michael Murphy5 Childhood Cancer Research Group, University of Oxford, Oxford, UKView further author information
,
Elaine C Johnstone6 Department of Clinical Pharmacology, University of Oxford, Oxford, UKView further author information
&
Marcus R Munafò7 Department of Experimental Psychology, University of BristolBristol, UKView further author information
 show all
Pages 357-367 | Published online: 17 Mar 2010

Bibliography

  • Broms U , SilventoinenK, MaddenPA, HeathAC, KaprioJ: Genetic architecture of smoking behavior: a study of Finnish adult twins.Twin Res. Hum. Genet.9(1) , 64–72 (2006).
  • Lessov CN , MartinNG, StathamDJ et al.: Defining nicotine dependence for genetic research: evidence from Australian twins.Psychol. Med.34(5) , 865–879 (2004).
  • Uhl GR , ElmerGI, LabudaMC, PickensRW: Genetic influences in drug abuse. In: Psychopharmacology: The Fourth Generation of Progress. Gloom FE, Kupfer DJ (Eds). Raven Press, NY, USA, 1793–2783 (1995).
  • Tsuang MT , LyonsMJ, MeyerJM et al.: Co-occurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities.Arch. Gen. Psychiatry55(11) , 967–972 (1998).
  • Karkowski LM , PrescottCA, KendlerKS: Multivariate assessment of factors influencing illicit substance use in twins from female–female pairs.Am. J. Med. Genet.96(5) , 665–670 (2000).
  • True WR , HeathAC, ScherrerJF et al.: Interrelationship of genetic and environmental influences on conduct disorder and alcohol and marijuana dependence symptoms.Am. J. Med. Genet.88(4) , 391–397 (1999).
  • Kendler KS , KarkowskiLM, NealeMC, PrescottCA: Illicit psychoactive substance use, heavy use, abuse, and dependence in a US population-based sample of male twins.Arch. Gen. Psychiatry57(3) , 261–269 (2000).
  • Uhl GR , LiuQR, DrgonT et al.: Molecular genetics of successful smoking cessation: convergent genome-wide association study results.Arch. Gen. Psychiatry65(6) , 683–693 (2008).
  • Drgon T , MontoyaI, JohnsonC et al.: Genome-wide association for nicotine dependence and smoking cessation success in NIH research volunteers.Mol. Med.15(1–2) , 21–27 (2009).
  • Uhl GR , DrgonT, LiuQR et al.: Genome-wide association for methamphetamine dependence: convergent results from 2 samples.Arch. Gen. Psychiatry65(3) , 345–355 (2008).
  • Uhl GR , LiuQR, DrgonT, JohnsonC, WaltherD, RoseJE: Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs.BMC Genet.8 , 10 (2007).
  • Bierut LJ , MaddenPA, BreslauN et al.: Novel genes identified in a high-density genome wide association study for nicotine dependence.Hum. Mol. Genet.16(1) , 24–35 (2007).
  • Thorgeirsson TE , GellerF, SulemP et al.: A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.Nature452(7187) , 638–642 (2008).
  • Amos CI , WuX, BroderickP et al.: Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.Nat. Genet.40(5) , 616–622 (2008).
  • Uhl GR , DrgonT, JohnsonC et al.: Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify “Connectivity Constellation” and drug target genes with pleiotropic effects.Ann. NY Acad. Sci.1141 , 318–381 (2008).
  • Drgon T , JohnsonC, WaltherD, AlbinoAP, RoseJE, UhlGR: Genome-wide association for smoking cessation success: participants in a trial with adjunctive denicotinized cigarettes.Mol. Med.15(7–8) , 268–274 (2009).
  • Aveyard P , BrownK, SaundersC et al.: Weekly versus basic smoking cessation support in primary care: a randomised controlled trial.Thorax62(10) , 898–903 (2007).
  • Johnson C , DrgonT, LiuQR et al.: Pooled association genome scanning for alcohol dependence using 104,268 SNPs: validation and use to identify alcoholism vulnerability loci in unrelated individuals from the collaborative study on the genetics of alcoholism.Am. J. Med. Genet. B Neuropsychiatr Genet141(8) , 844–853 (2006).
  • Liu QR , DrgonT, WaltherD et al.: Pooled association genome scanning: validation and use to identify addiction vulnerability loci in two samples.Proc. Natl Acad. Sci. USA102(33) , 11864–11869 (2005).
  • Uhl GR , LiuQR, WaltherD, HessJ, NaimanD: Polysubstance abuse-vulnerability genes: Genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms.Am. J. Hum. Genet.69(6) , 1290–1300 (2001).
  • Liu QR , DrgonT, JohnsonC, WaltherD, HessJ, UhlGR: Addiction molecular genetics: 639,401 SNP whole genome association identifies many “cell adhesion” genes.Am. J. Med. Genet. B Neuropsychiatr. Genet.141B(8) , 918–925 (2006).
  • Dupont WD , PlummerWD Jr: Power and sample size calculations. A review and computer program. Control Clin. Trials11(2) , 116–128 (1990).
  • Dupont WD , PlummerWD Jr: Power and sample size calculations for studies involving linear regression. Control Clin. Trials19(6) , 589–601 (1998).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.