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Research Article

TNF-α -857 and -1031 Polymorphisms Predict Good Therapeutic Response to TNF-α Blockers in Chinese Han Patients with Ankylosing Spondylitis

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Pages 1459-1467 | Published online: 12 Oct 2012

References

  • Huang F , ZhangJ, HuangJL et al. A multicenter, double-blind, placebo-controlled, randomized, Phase III clinical study of etanercept in treatment of ankylosing spondylitis. Chin. J. Intern. Med. 49(9) , 741–745 (2010).
  • Pavy S , ToonenEJ, Miceli-RichardC et al. Tumour necrosis factor α -308G->A polymorphism is not associated with response to TNF α blockers in Caucasian patients with rheumatoid arthritis: systematic review and meta-analysis. Ann. Rheum. Dis 69(6) , 1022–1028 (2010).
  • Seitz M , WirthmüllerU, MöllerB, VilligerPM. The -308 tumour necrosis factor-α gene polymorphism predicts therapeutic response to TNF α-blockers in rheumatoid arthritis and spondyloarthritis patients. Rheumatology (Oxford)46(1) , 93–96 (2007).
  • Lee YH , JiJD, BaeSC, SongGG. Associations between tumor necrosis factor-α (TNF-α) -308 and -238 G/A polymorphisms and shared epitope status and responsiveness to TNF-α blockers in rheumatoid arthritis: a metaanalysis update. J. Rheumatol.37(4) , 740–746 (2010).
  • Ingegnoli F , FavalliEG, MeroniPL. Does polymorphysm of genes coding for pro-inflammatory mediators predict the clinical response to TNF α blocking agents? A review analysis of the literature. Autoimmun. Rev.10(8) , 460–463 (2011).
  • Liu C , BatliwallaF, LiW et al. Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis. Mol. Med. 14(9–10) , 575–581 (2008).
  • Lequerré T , VittecoqO, Le Loët X. Comments about the editorial by Bénédicte Mugnier and Jean Roudier entitled “Factors predicting responsiveness to anti-TNFalpha therapy in patients with rheumatoid arthritis: using biotherapies rationally”. Joint Bone Spine72(4) , 346–347 (2005).
  • Balog A , KlauszG, GálJ et al. Investigation of the prognostic value of TNF-α gene polymorphism among patients treated with infliximab, and the effects of infliximab therapy on TNF-α production and apoptosis. Pathobiology 71(5) , 274–280 (2004).
  • Vasilopoulos Y , ManolikaM, ZafiriouE et al. Pharmacogenetic analysis of TNF, TNFRSF1A, and TNFRSF1B gene polymorphisms and prediction of response to anti-TNF therapy in psoriasis patients in the Greek population. Mol. Diagn. Ther. 16(1) , 29–34 (2012).
  • Prajapati R , PlantD, BartonA. Genetic and genomic predictors of anti-TNF response. Pharmacogenomics12(11) , 1571–1585 (2011).
  • Sousa E , Caetano-LopesJ, PintoP et al. Ankylosing spondylitis susceptibility and severity – contribution of TNF gene promoter polymorphisms at positions -238 and -308. Ann. NY Acad. Sci. 1173 , 581–588 (2009).
  • Fonseca JE , CarvalhoT, CruzM et al. Polymorphism at position -308 of the tumour necrosis factor α gene and rheumatoid arthritis pharmacogenetics. Ann. Rheum. Dis 64(5) , 793–794 (2005).
  • Lee YH , SongGG. Lack of association of TNF-α promoter polymorphisms with ankylosing spondylitis: a meta-analysis. Rheumatology (Oxford)48(11) , 1359–1362 (2009).
  • Romero-Sánchez C , LondoñoJ, DelgadoG et al. Association of tumor necrosis factor α-308 promoter polymorphism with spondyloarthritides patients in Colombia. Rheumatol. Int. 32(7) , 2195–2197 (2012).
  • Chatzikyriakidou A , GeorgiouI, VoulgariPV, DrososAA. The role of tumor necrosis factor (TNF)-α and TNF receptor polymorphisms in susceptibility to ankylosing spondylitis. Clin. Exp. Rheumatol.27(4) , 645–648 (2009).
  • Li B , WangP, LiH. The association between TNF-α promoter polymorphisms and ankylosing spondylitis: a meta-analysis. Clin. Rheumatol.29(9) , 983–990 (2010).
  • Poddubnyy DA , Märker-HermannE, Kaluza-SchillingW et al. Relation of HLA-B27, tumor necrosis factor-α promoter gene polymorphisms, and T cell cytokine production in ankylosing spondylitis – a comprehensive genotype–phenotype analysis from an observational cohort. J. Rheumatol. 38(11) , 2436–2441 (2011).
  • Zinovieva E , BourgainC, KadiA et al. Comprehensive linkage and association analyses identify haplotype, near to the TNFSF15 gene, significantly associated with spondyloarthritis. PLoS Genet. 5(6) , e1000528 (2009).
  • Lu MC , YangKL, TungCH et al. Higher LPS-stimulated TNF-α mRNA levels in peripheral blood mononuclear cells from Chinese ankylosing spondylitis patients with -308G/A polymorphism in promoter region of tumor necrosis factor: association with distinct A33/B58/Cw10haplotypes. Rheumatol. Int. 29(2) , 189–195 (2008).
  • Brown MA . Re: Zhu et al, “A novel gene variation of TNF alpha associated with ankylosing spondylitis: a reconfirmed study”. Ann. Rheum. Dis67(3) , 434; discussion 434–436 (2008).
  • Nicknam MH , MahmoudiM, AmirzargarAA, JamshidiAR, RezaeiN, NikbinB. HLA-B27 subtypes and tumor necrosis factor α promoter region polymorphism in Iranian patients with ankylosing spondylitis. Eur. Cytokine Netw.20(1) , 17–20 (2009).
  • Shiau MY , LoMK, ChangCP, YangTP, HoKT, ChangYH. Association of tumour necrosis factor α promoter polymorphisms with ankylosing spondylitis in Taiwan. Ann. Rheum. Dis66(4) , 562–563 (2007).
  • Vargas-Alarcón G , Casasola-VargasJ, Rodríguez-PérezJM et al. Tumor necrosis factor-α promoter polymorphisms in Mexican patients with spondyloarthritis. Hum. Immunol. 67(10) , 826–832 (2006).
  • Davidson SI , LiuY, DanoyPA et al. Association of STAT3 and TNFRSF1A with AS in Han Chinese; ARD 2011 – investigating the susceptibility to AS in Han Chinese. Ann. Rheum. Dis 70(2) , 289–292 (2011).
  • Huang F , ZhangF, ZhengY et al. A multicenter, double-blind, randomized, placebo-controlled clinical trial of etanercept treatment of Chinese patients with active ankylosing spondylitis. Chin. J. Intern. Med. 50(12) , 1043–1047 (2011).
  • Van der Linden S , ValkenburgHA, CatsA. Evaluation of diagnostic criteria for ankylosing spondylitis: a proposal for modification of the New York criteria. Arthritis Rheum.27(4) , 361–368 (1984).
  • Garrett S , JenkinsonT, KennedyLG et al. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J. Rheumatol. 21(12) , 2286–2291 (1994).
  • Anderson JJ , BaronG, van der Heijde D et al. Ankylosing spondylitis assessment group preliminary definition of short-term improvement in ankylosing spondylitis. Arthritis Rheum.44(8) , 1876–1886 (2001).
  • Chung WT , ChoeJY, JangWC et al. Polymorphisms of tumor necrosis factor-α promoter region for susceptibility to HLA-B27-positive ankylosing spondylitis in Korean population. Rheumatol. Int. 31(9) , 1167–1175 (2011).
  • Marotte H , ArnaudB, DiasparraJ, ZrioualS, MiossecP. Association between the level of circulating bioactive tumor necrosis factor α and the tumor necrosis factor α gene polymorphism at -308 in patients with rheumatoid arthritis treated with a tumor necrosis factor α inhibitor. Arthritis Rheum.58(5) , 1258–1263 (2008).
  • Kooloos WM , WesselsJA, van der Straaten T, Huizinga TW, Guchelaar HJ. Criteria for the selection of single nucleotide polymorphisms in pathway pharmacogenetics: TNF inhibitors as a case study. Drug Discov. Today14(17–18) , 837–844 (2009).
  • Lv K , ChenR, CaiQ, FangM, SunS. Effects of a single nucleotide polymorphism on the expression of human tumor necrosis factor-α. Scand. J. Immunol.64(2) , 164–169 (2006).
  • Guis S , BalandraudN, BouvenotJ et al. Influence of -308 A/G polymorphism in the tumor necrosis factor α gene on etanercept treatment in rheumatoid arthritis. Arthritis Rheum. 57(8) , 1426–1430 (2007).
  • Aguillón JC , CruzatA, AravenaO, SalazarL, LlanosC, CuchacovichM. Could single-nucleotide polymorphisms (SNPs) affecting the tumour necrosis factor promoter be considered as part of rheumatoid arthritis evolution? Immunobiology211(1–2) , 75–84 (2006).
  • Soto L , SabugoF, CatalanD et al. The presence of anti-citrullinated protein antibodies (ACPA) does not affect the clinical response to adalimumab in a group of RA patients with the tumor necrosis factor (TNF) α-308 G/G promoter polymorphism. Clin. Rheumatol. 30(3) , 391–395 (2011).
  • Plant D , BowesJ, PotterC et al. Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci. Arthritis Rheum. 63(3) , 645–653 (2011).
  • Suarez-Gestal M , Perez-PampinE, CalazaM, Gomez-ReinoJJ, Gonzalez.A Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study. Arthritis Res. Ther.12(2) , R72 (2010).
  • Potter C , GibbonsLJ, BowesJD et al. Polymorphisms spanning the TNFR2 and TACE genes do not contribute towards variable anti-TNF treatment response. Pharmacogenet. Genomics 20(5) , 338–341 (2010).
  • O‘Rielly DD , RoslinNM, BeyeneJ, PopeA, RahmanP. TNF-α-308 G/A polymorphism and responsiveness to TNF-α blockade therapy in moderate to severe rheumatoid arthritis: a systematic review and meta-analysis. Pharmacogenomics J.9(3) , 161–167 (2009).
  • Maxwell JR , PotterC, HyrichKL et al. Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis. Hum. Mol. Genet. 17(22) , 3532–3538 (2008).
  • Ongaro A , De Mattei M, Pellati A et al. Can tumor necrosis factor receptor II gene 676T>G polymorphism predict the response grading to anti-TNFα therapy in rheumatoid arthritis? Rheumatol. Int.28(9) , 901–908 (2008).
  • Kang CP , LeeKW, YooDH, KangC, BaeSC. The influence of a polymorphism at position -857 of the tumour necrosis factor a gene on clinical response to etanercept therapy in rheumatoid arthritis. Rheumatology44(4) , 547–552 (2005).

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