References
- Dumontet C , MorschhauserF, Solal-CelignyP et al. Gemcitabine as a single agent in the treatment of relapsed or refractory low-grade non-Hodgkin‘s lymphoma. Br. J. Haematol. 113(3) , 772–778 (2001).
- Metro G , CappuzzoF, FinocchiaroG, ToschiL, CrinoL. Development of gemcitabine in non-small cell lung cancer: the Italian contribution. Ann. Oncol.17(Suppl. 5) , V37–V46 (2006).
- McDonagh EM , Whirl-CarrilloM, GartenY, AltmanRB, KleinTE. From pharmacogenomic knowledge acquisition to clinical applications: the PharmGKB as a clinical pharmacogenomic biomarker resource. Biomark. Med.5(6) , 795–806 (2011).
- Mini E , NobiliS, CaciagliB, LandiniI, MazzeiT. Cellular pharmacology of gemcitabine. Ann. Oncol.17(Suppl. 5) , V7–V12 (2006).
- Plunkett W , HuangP, XuYZ, HeinemannV, GrunewaldR, GandhiV. Gemcitabine: metabolism, mechanisms of action, and self-potentiation. Semin. Oncol.22(4 Suppl. 11) , 3–10 (1995).
- Rosell R , CoboM, IslaD, CampsC, MassutiB. Pharmacogenomics and gemcitabine. Ann. Oncol.17(Suppl. 5) , V13–V16 (2006).
- Erculj N , KovacV, HmeljakJ, FrankoA, Dodic-FikfakM, DolzanV. The influence of gemcitabine pathway polymorphisms on treatment outcome in patients with malignant mesothelioma. Pharmacogenet. Genomics22(1) , 58–68 (2012).
- Wong AL , YapHL, YeoWL et al. Gemcitabine and platinum pathway pharmacogenetics in Asian breast cancer patients. Cancer Genomics Proteomics 8(5) , 255–259 (2011).
- Kirstein MN , HassanI, GuireDE et al. High-performance liquid chromatographic method for the determination of gemcitabine and 2´,2´-difluorodeoxyuridine in plasma and tissue culture media. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 835(1–2) , 136–142 (2006).
- Veltkamp SA , HillebrandMJ, RosingH et al. Quantitative analysis of gemcitabine triphosphate in human peripheral blood mononuclear cells using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry. J. Mass Spectrom. 41(12) , 1633–1642 (2006).
- Cheung RK , GrinsteinS, GelfandEW. Volume regulation by human lymphocytes. Identification of differences between the two major lymphocyte subpopulations. J. Clin. Invest.70(3) , 632–638 (1982).
- Tham LS , WangL, SooRA et al. A pharmacodynamic model for the time course of tumor shrinkage by gemcitabine + carboplatin in non-small cell lung cancer patients. Clin. Cancer Res. 14(13) , 4213–4218 (2008).
- Mitra AK , CrewsKR, PoundsS et al. Genetic variants in cytosolic 5´-nucleotidase II are associated with its expression and cytarabine sensitivity in HapMap cell lines and in patients with acute myeloid leukemia. J. Pharmacol. Exp. Ther. 339(1) , 9–23 (2011).
- Li L , SchaidDJ, FridleyBL et al. Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer. Pharmacogenet. Genomics 22(2) , 105–116 (2012).
- Ludovini V , FlorianiI, PistolaL et al. Association of cytidine deaminase and xeroderma pigmentosum group D polymorphisms with response, toxicity, and survival in cisplatin/gemcitabine-treated advanced non-small cell lung cancer patients. J. Thorac. Oncol. 6(12) , 2018–2026 (2011).
- Okazaki T , JavleM, TanakaM, AbbruzzeseJL, LiD. Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity. Clin. Cancer Res.16(1) , 320–329 (2010).
- Soo RA , WangLZ, NgSS et al. Distribution of gemcitabine pathway genotypes in ethnic Asians and their association with outcome in non-small cell lung cancer patients. Lung Cancer 63(1) , 121–127 (2009).
- Tibaldi C , GiovannettiE, TiseoM et al. Correlation of cytidine deaminase polymorphisms and activity with clinical outcome in gemcitabine-/platinum-treated advanced non-small-cell lung cancer patients. Ann. Oncol. 23(3) , 670–677 (2012).
- Ryu JS , ShinES, NamHS et al. Differential effect of polymorphisms of CMPK1 and RRM1 on survival in advanced non-small cell lung cancer patients treated with gemcitabine or taxane/cisplatinum. J. Thorac. Oncol. 6(8) , 1320–1329 (2011).
- Gusella M , PasiniF, BolzonellaC et al. Equilibrative nucleoside transporter 1 genotype, cytidine deaminase activity and age predict gemcitabine plasma clearance in patients with solid tumours. Br. J. Clin. Pharmacol. 71(3) , 437–444 (2011).