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Preliminary Communication

Rapid Deaminator Status is Associated With Poor Clinical Outcome in Pancreatic Cancer Patients Treated with a Gemcitabine-Based Regimen

, , , , , , , & show all
Pages 1047-1051 | Published online: 09 Jul 2013

References

  • Ciccolini J , MercierC, DahanL, AndreN. Integrating pharmacogenetics into gemcitabine dosing – time for a change? Nat. Rev. Clin. Oncol.8(7) , 439–444 (2011).
  • Tibaldi C , GiovannettiE, VasileE et al. Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients. Clin. Cancer Res. 14(6) , 1797–1803 (2008).
  • Yonemori K , UenoH, OkusakaT et al. Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin. Clin. Cancer Res. 11(7) , 2620–2624 (2005).
  • Caronia D , MartinM, SastreJ et al. A polymorphism in the cytidine deaminase promoter predicts severe capecitabine-induced hand–foot syndrome. Clin. Cancer Res. 17(7) , 2006–2013 (2011).
  • Ciccolini J , EvrardA, LacarelleB. A CDD polymorphism as predictor of capecitabine-induced hand–foot syndrome – letter. Clin. Cancer Res.18(1) , 317 (2012).
  • Ciccolini J , EvrardA, M‘BatchiL et al. CDA deficiency as a possible culprit for life-threatening toxicities after cytarabine plus 6-mercaptopurine therapy: pharmacogenetic investigations. Pharmacogenomics 13(4) , 393–397 (2012).
  • Ciccolini J , DahanL, AndreN et al. Cytidine deaminase residual activity in serum is a predictive marker of early severe toxicities in adults after gemcitabine-based chemotherapies. J. Clin. Oncol. 28(1) , 160–165 (2010).
  • Mercier C , DahanL, OuafikL, AndreN, CiccoliniJ. Letter to the editor: pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism. Eur. J. Clin. Pharmacol.66(9) , 959–960 (2010).
  • Giovannetti E , TibaldiC, FalconeA, DanesiR, PetersGJ. Impact of cytidine deaminase polymorphisms on toxicity after gemcitabine: the question is still ongoing. J. Clin. Oncol.28(14) , e221–e222; author reply e223–e225 (2010).
  • Mercier C , RaynalC, DahanL et al. Toxic death case in a patient undergoing gemcitabine-based chemotherapy in relation with cytidine deaminase downregulation. Pharmacogenet. Genomics 17(10) , 841–844 (2007).
  • Sugiyama E , KaniwaN, KimSR et al. Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism. J. Clin. Oncol. 25(1) , 32–42 (2007).
  • Andre F , McShaneLM, MichielsS et al. Biomarker studies: a call for a comprehensive biomarker study registry. Nat. Rev. Clin. Oncol. 8(3) , 171–176 (2011).
  • O‘Reilly EM . Adjuvant therapy for pancreas adenocarcinoma. J. Surg. Oncol.107(1) , 78–85 (2013).
  • von Hoff DD , RamanathanRK, BoradMJ et al. Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a Phase I/II trial. J. Clin. Oncol. 29(34) , 4548–4554 (2011).
  • Dahan L , CiccoliniJ, EvrardA et al. Sudden death related to toxicity in a patient on capecitabine and irinotecan plus bevacizumab intake: pharmacogenetic implications. J. Clin. Oncol. 30(4) , e41–e44 (2012).
  • Tibaldi C , GiovannettiE, TiseoM et al. Correlation of cytidine deaminase polymorphisms and activity with clinical outcome in gemcitabine-/platinum-treated advanced non-small-cell lung cancer patients. Ann. Oncol. 23(3) , 670–677 (2012).
  • Bengala C , GuarneriV, GiovannettiE et al. Prolonged fixed dose rate infusion of gemcitabine with autologous haemopoietic support in advanced pancreatic adenocarcinoma. Br. J. Cancer 93(1) , 35–40 (2005).

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