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Research Article

URAT1 Gene Polymorphisms Influence Uricosuric Action of Losartan in Hypertensive Patients with Hyperuricemia

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Pages 855-863 | Published online: 18 Jun 2015

References

  • Hamada T , HisatomeI , KinugasaYet al. Effect of the angiotensin II receptor antagonist losartan on uric acid and oxypurine metabolism in healthy subjects . Intern. Med.41 ( 10 ), 793 – 797 ( 2002 ).
  • Nakashima M , UematsuT , KosugeK , KanamaruM . Pilot study of the uricosuric effect of DuP-753, a new angiotensin II receptor antagonist, in healthy subjects . Eur. J. Clin. Pharmacol.42 ( 3 ), 333 – 335 ( 1992 ).
  • Puig JG , MateosF , BunoA , OrtegaR , RodriguezF , Dal-ReR . Effect of eprosartan and losartan on uric acid metabolism in patients with essential hypertension . J. Hypertension17 ( 7 ), 1033 – 1039 ( 1999 ).
  • Schmitt F , NatovS , MartinezF , LacourB , HannedoucheTP . Renal effects of angiotensin I-receptor blockade and angiotensin convertase inhibition in man . Clin. Sci.90 ( 3 ), 205 – 213 ( 1996 ).
  • Rayner BL , TrinderYA , BainesD , IsaacsS , OpieLH . Effect of losartan versus candesartan on uric acid, renal function, and fibrinogen in patients with hypertension and hyperuricemia associated with diuretics . Am. J. Hypertension19 ( 2 ), 208 – 213 ( 2006 ).
  • Enomoto A , EndouH . Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease . Clin. Exp. Nephrol.9 ( 3 ), 195 – 205 ( 2005 ).
  • Iwanaga T , SatoM , MaedaT , OgiharaT , TamaiI . Concentration-dependent mode of interaction of angiotensin II receptor blockers with uric acid transporter . J. Pharmacol. Exp. Ther.320 ( 1 ), 211 – 217 ( 2007 ).
  • Burnier M , Roch-RamelF , BrunnerHR . Renal effects of angiotensin II receptor blockade in normotensive subjects . Kidney Int.49 ( 6 ), 1787 – 1790 ( 1996 ).
  • Enomoto A , KimuraH , ChairoungduaAet al. Molecular identification of a renal urate anion exchanger that regulates blood urate levels . Nature417 ( 6887 ), 447 – 452 ( 2002 ).
  • Roch-Ramel F , GuisanB , DieziJ . Effects of uricosuric and antiuricosuric agents on urate transport in human brush-border membrane vesicles . J. Pharmacol. Exp. Ther.280 ( 2 ), 839 – 845 ( 1997 ).
  • Alderman MH , CohenH , MadhavanS , KivlighnS . Serum uric acid and cardiovascular events in successfully treated hypertensive patients . Hypertension34 ( 1 ), 144 – 150 ( 1999 ).
  • Nindita Y , HamadaT , BahrudinUet al. Effect of losartan and benzbromarone on the level of human urate transporter 1 mRNA . Arzneimittelforschung60 ( 4 ), 186 – 188 ( 2010 ).
  • Roch-Ramel F , WernerD , GuisanB . Urate transport in brush-border membrane of human kidney . Am. J. Physiol.266 ( 5 Pt 2 ), F797 – F805 ( 1994 ).
  • Jutabha P , KanaiY , HosoyamadaMet al. Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule . J. Biol. Chem.278 ( 30 ), 27930 – 27938 ( 2003 ).
  • Hamada T , IchidaK , HosoyamadaMet al. Uricosuric action of losartan via the inhibition of urate transporter 1 (URAT 1) in hypertensive patients . Am. J. Hypertension21 ( 10 ), 1157 – 1162 ( 2008 ).
  • Fujimori S , OkaY , OgataN , EtoK . Effects of losartan/hydrochlorothiazide on serum uric acid levels and blood pressure in hypertensive patients . Nucleosides Nucleotides Nucleic Acids30 ( 12 ), 1030 – 1034 ( 2011 ).
  • Sui X , ChurchTS , MeriwetherRA , LobeloF , BlairSN . Uric acid and the development of metabolic syndrome in women and men . Metabolism57 ( 6 ), 845 – 852 ( 2008 ).
  • Sweet CS , BradstreetDC , BermanRS , JallardN , SaenzA , WeidlerDJ . Pharmacodynamic activity of intravenous E-3174, an angiotensin II antagonist, in patients with essential hypertension . Am. J. Hypertension7 ( 12 ), 1035 – 1040 ( 1994 ).
  • Dang A , ZhangY , LiuG , ChenG , SongW , WangB . Effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia in Chinese population . J. Hum. Hypertension20 ( 1 ), 45 – 50 ( 2006 ).
  • Hosoya T , KuriyamaS , YoshizawaT , KobayashiA , OtsukaY , OhnoI . Effects of combined antihypertensive therapy with losartan/hydrochlorothiazide on uric acid metabolism . Intern. Med.51 ( 18 ), 2509 – 2514 ( 2012 ).
  • Graessler J , GraesslerA , UngerSet al. Association of the human urate transporter 1 with reduced renal uric acid excretion and hyperuricemia in a German Caucasian population . Arthritis Rheum.54 ( 1 ), 292 – 300 ( 2006 ).
  • Iwai N , MinoY , HosoyamadaM , TagoN , KokuboY , EndouH . A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese . Kidney Int.66 ( 3 ), 935 – 944 ( 2004 ).
  • Jang WC , NamYH , ParkSMet al. T6092C polymorphism of SLC22A12 gene is associated with serum uric acid concentrations in Korean male subjects . Clin. Chim. Acta398 ( 1–2 ), 140 – 144 ( 2008 ).
  • Wurzner G , GersterJC , ChioleroAet al. Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia and gout . J. Hypertension19 ( 10 ), 1855 – 1860 ( 2001 ).
  • Ohshiro K , SakimaA , NakadaSet al. Beneficial effect of switching from a combination of angiotensin II receptor blockers other than losartan and thiazides to a fixed dose of losartan/hydrochlorothiazide on uric acid metabolism in hypertensive patients . Clin. Exp. Hypertension33 ( 8 ), 565 – 570 ( 2011 ).
  • Hamada T , MizutaE , KondoTet al. Effects of a low-dose antihypertensive diuretic in combination with losartan, telmisartan, or candesartan on serum urate levels in hypertensive patients . Arzneimittelforschung60 ( 2 ), 71 – 75 ( 2010 ).
  • Shima Y TK , OhtaH . Association between intronic SNP in urate-anion exchanger gene, SLC22A12, and serum uric acid levels in Japanese . Life Sci.79 ( 23 ), 2234 – 2237 ( 2006 ).