Clinical Pharmacogenomics: Patient Perspectives of Pharmacogenomic Testing and the Incidence of Actionable Test Results in a Chronic Disease Cohort

References

• Alessandrini M , ChaudhryM , DodgenTM , PepperMS . Pharmacogenomics and global precision medicine in the context of adverse drug reactions: top 10 opportunities and challenges for the next decade . OMICS20 ( 10 ), 593 – 603 ( 2016 ).
   PubMed Web of Science ®Google Scholar
• Haga SB , BurkeW , GinsburgGS , MillsR , AgansR . Primary care physicians’ knowledge of and experience with pharmacogenetic testing . Clin. Genet.82 ( 4 ), 388 – 394 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Stanek EJ , SandersCL , TaberKAet al. Adoption of pharmacogenomic testing by US physicians: results of a nationwide survey . Clin. Pharmacol. Ther.91 ( 3 ), 450 – 458 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Shields AE , NajafzadehM , SchachterAB . Bumps along the translational pathway: anticipating uptake of tailored smoking cessation treatment . Per. Med.10 ( 8 ), 813 – 825 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Haga SB , LaPointeNM . The potential impact of pharmacogenetic testing on medication adherence . Pharmacogenomics J.13 ( 6 ), 481 – 483 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Hoop JG , LapidMI , PaulsonRM , RobertsLW . Clinical and ethical considerations in pharmacogenetic testing: views of physicians in 3 “early adopting” departments of psychiatry . J. Clin. Psychiatry71 ( 6 ), 745 – 753 ( 2010 ).
   PubMed Web of Science ®Google Scholar
• Overby CL , ErwinAL , Abul-HusnNSet al. Physician attitudes toward adopting genome-guided prescribing through clinical decision support . J. Pers. Med.4 ( 1 ), 35 – 49 ( 2014 ).
   PubMedGoogle Scholar
• Raghavan S , VassyJL . Do physicians think genomic medicine will be useful for patient care?Per. Med.11 ( 4 ), 424 – 433 ( 2014 ).
   PubMed Web of Science ®Google Scholar
• Bernhardt BA , ZayacC , GordonES , WawakL , PyeritzRE , GollustSE . Incorporating direct-to-consumer genomic information into patient care: attitudes and experiences of primary care physicians . Per. Med.9 ( 7 ), 683 – 692 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Fargher EA , EddyC , NewmanWet al. Patients’ and healthcare professionals’ views on pharmacogenetic testing and its future delivery in the NHS . Pharmacogenomics8 ( 11 ), 1511 – 1519 ( 2007 ).
   PubMed Web of Science ®Google Scholar
• Mountcastle-Shah E , HoltzmanNA . Primary care physicians’ perceptions of barriers to genetic testing and their willingness to participate in research . Am. J. Med. Genet.94 ( 5 ), 409 – 416 ( 2000 ).
   PubMed Web of Science ®Google Scholar
• Zachry WM , ArmstrongEP . Health care professionals’ perceptions of the role of pharmacogenomic data . J. Manag. Care Pharm.8 ( 4 ), 278 – 284 ( 2002 ).
   PubMedGoogle Scholar
• Mai Y , KoromilaT , SagiaAet al. A critical view of the general public’s awareness and physicians’ opinion of the trends and potential pitfalls of genetic testing in Greece . Per. Med.8 ( 5 ), 551 – 561 ( 2011 ).
   PubMed Web of Science ®Google Scholar
• Rogausch A , PrauseD , SchallenbergA , BrockmollerJ , HimmelW . Patients’ and physicians’ perspectives on pharmacogenetic testing . Pharmacogenomics7 ( 1 ), 49 – 59 ( 2006 ).
   PubMed Web of Science ®Google Scholar
• Haga SB , MillsR , MoaddebJ , Allen LapointeN , ChoA , GinsburgGS . Patient experiences with pharmacogenetic testing in a primary care setting . Pharmacogenomics17 ( 15 ), 1629 – 1636 ( 2016 ).
   PubMed Web of Science ®Google Scholar
• Gibson ML , HohmeierKC , SmithCT . Pharmacogenomics testing in a community pharmacy: patient perceptions and willingness-to-pay . Pharmacogenomics18 ( 3 ), 227 – 233 ( 2017 ).
   PubMed Web of Science ®Google Scholar
• Olson JE , Rohrer VitekCR , BellEJet al. Participant-perceived understanding and perspectives on pharmacogenomics: the Mayo Clinic RIGHT protocol (Right Drug, Right Dose, Right Time) . Genet. Med.19 ( 7 ), 819 – 825 ( 2017 ).
   PubMed Web of Science ®Google Scholar
• Bielinski SJ , St SauverJL , OlsonJEet al. Are patients willing to incur out-of-pocket costs for pharmacogenomic testing? Pharmacogenomics 17 ( 1 ), 1 – 3 ( 2017 ).
   Web of Science ®Google Scholar
• Sweet K , SturmAC , SchmidlenTet al. Outcomes of a randomized controlled trial of genomic counseling for patients receiving personalized and actionable complex disease reports . J. Genet. Couns. doi:10.1007/s10897-017-0073-z ( 2016 ) ( Epub ahead of print ).
   Web of Science ®Google Scholar
• Keller MA , GordonES , StackCBet al. Coriell personalized medicine collaborative: a prospective study of the utility of personalized medicine . Per. Med.7 ( 3 ), 301 – 317 ( 2010 ).
   PubMed Web of Science ®Google Scholar
• Sturm AC , SweetK , ManickamK . Implementation of a clinical research pharmacogenomics program at an academic medical center: role of the genetics healthcare professional . Pharmacogenomics14 ( 7 ), 703 – 706 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Sweet K , GordonES , SturmACet al. Design and implementation of a randomized controlled trial of genomic counseling for patients with chronic disease . J. Pers. Med.4 ( 1 ), 1 – 19 ( 2014 ).
   PubMedGoogle Scholar
• Bristol-Myers Squibb . Coumadin (warfarin sodium) Prescribing Information . September 2016 . packageinserts.bms.com/pi/pi_coumadin.pdf .
   Google Scholar
• Scott SA , SangkuhlK , SteinCMet al. The Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for cytochrome P450–2C19 (CYP2C19) genotype and clopidogrel therapy: 2013 Update . Clin. Pharm. Ther.94 ( 3 ), 317 – 323 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Ramsey LB , JohnsonSG , CaudleKEet al. The Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for SLCO1B1 and simvastatin-induced myopathy: 2014 update . Clin. Pharm. Ther.96 ( 4 ), 423 – 428 ( 2014 ).
   PubMed Web of Science ®Google Scholar
• Rosenberg NA , MahajanS , RamachandranS , ZhaoC , PritchardJK , FeldmanMW . Clines, clusters, and the effect of study design on the inference of human population structure . PLoS Genet.1 ( 6 ), e70 ( 2005 ).
   PubMed Web of Science ®Google Scholar
• Rosenberg NA , PritchardJK , WeberJLet al. Genetic structure of human populations . Science298 ( 5602 ), 2381 – 2385 ( 2002 ).
   PubMed Web of Science ®Google Scholar
• Jakobsson M , ScholzSW , ScheetPet al. Genotype, haplotype and copy-number variation in worldwide human populations . Nature451 ( 7181 ), 998 – 1003 ( 2008 ).
   PubMed Web of Science ®Google Scholar
• Lee KC , HudmonKS , MaJD , KuoGM . Evaluation of a shared pharmacogenomics curriculum for pharmacy students . Pharmacogenomics16 ( 4 ), 315 – 322 ( 2015 ).
   PubMed Web of Science ®Google Scholar
• Luzum JA , LuzumMJ . Physicians’ attitudes toward pharmacogenetic testing before and after pharmacogenetic education . Per. Med.13 ( 2 ), 119 – 127 ( 2016 ).
   PubMed Web of Science ®Google Scholar
• Crews KR , CrossSJ , McCormickJNet al. Development and implementation of a pharmacist-managed clinical pharmacogenetics service . Am. J. Health Syst. Pharm.68 ( 2 ), 143 – 150 ( 2011 ).
   PubMed Web of Science ®Google Scholar
• Freimuth RR , FormeaCM , HoffmanJMet al. Implementing genomic clinical decision support for drug-based precision medicine . CPT Pharmacometrics Syst. Pharmacol.6 ( 3 ), 153 – 155 ( 2017 ).
   PubMedGoogle Scholar
• Rasmussen LV , OverbyCL , ConnollyJet al. Practical considerations for implementing genomic information resources. Experiences from eMERGE and CSER . Appl. Clin. Inform.7 ( 3 ), 870 – 882 ( 2016 ).
   PubMed Web of Science ®Google Scholar
• Caraballo PJ , BielinskiSJ , St SauverJL , WeinshilboumRM . Electronic medical record-integrated pharmacogenomics and related clinical decision support concepts . Clin. Pharmacol. Ther.102 ( 2 ), 254 – 264 ( 2017 ).
   PubMed Web of Science ®Google Scholar