1,020
Views
0
CrossRef citations to date
0
Altmetric
Editorial

The 1000 Genomes Project: Paving the way for Personalized Genomic Medicine

, &
Pages 321-324 | Published online: 06 Jun 2013

References

  • Shendure J , HanleeJ. Next-generation DNA sequencing. Nat. Biotech.26(10) , 1135–1145 (2008).
  • Metzker ML . Sequencing technologies – the next generation. Nat. Rev. Genet.11(1) , 31–46 (2010).
  • International Human Genome Sequencing Consortium: Initial sequencing and analysis of the human genome. Nature409(6822) , 860–921 (2001).
  • Venter JC , AdamsMD, MyersEW et al. The sequence of the human genome. Science 291(5507) , 1304–1351 (2001).
  • The International HapMap Consortium. A haplotype map of the human genome. Nature437(27) , 1299–1320 (2005).
  • The International HapMap Consortium. A second generation human haplotype map of over 3.1 million SNPs. Nature449(18) , 851–862 (2007).
  • The International HapMap 3 Consortium. Integrating common and rare genetic variation in diverse human populations. Nature467(2) , 52–58 (2010).
  • Manolio TA , CollinsFS, CoxNJ et al. Finding the missing heritability of complex diseases. Nature 461 , 747–753 (2009).
  • The 1000 Genomes Project Consortium. A map of human genome variation from population-scale sequencing. Nature467 , 1061–1073 (2010).
  • The 1000 Genomes Project Consortium. An integrated map of genetic variation from 1,092 human genomes. Nature491 , 56–65 (2012).
  • Grossman SR , AndersenKG, ShlyakhterI et al. Identifying recent adaptations in large-scale genomic data. Cell 152(4) , 703–713 (2013).
  • Lu JT , WangY, GibbsRA, YuF. Characterizing linkage disequilibrium and evaluating imputation power of human genomic insertion-deletion polymorphisms. Genome Biol.13 , R15 (2012).
  • Sudmant PH , KitzmanJO, AntonacciF et al. Diversity of human copy number variation and multicopy genes. Science 330(6004) , 641–646 (2010).
  • Marth GT , YuF, IndapAR et al. The functional spectrum of low-frequency coding variation. Genome Biol. 12(9) , R84 (2011).
  • Choi M , SchollUI, JiW et al. Genetic diagnosis by whole exome capture and massively parallel DNA sequencing. Proc. Natl Acad. Sci. USA 106(45) , 19096–19101 (2009).
  • Slamon DJ , ClarkGM, WongSG, LevinWJ, UllrichA, McGuireWL. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science235(4785) , 177–182 (1987).
  • Emmelkamp JM , RockstrohJK. CCR5 antagonists: comparison of efficacy, side effects, pharmacokinetics and interactions – review of the literature. Eur. J. Med. Res.12(9) , 409–417 (2007).
  • Crunkhorn S . Trial watch: PCSK9 antibody reduces LDL cholesterol. Nat. Rev. Drug Discov.11(1) , 11 (2012).
  • Wang QY , SongJ, GibbsRA, BoerwinkleE, DongJF, YuF. Characterizing polymorphisms and allelic diversity of von Willebrand factor gene in the 1000 Genomes. J. Thromb. Haemost.11 , 261–269 (2013).
  • Hua F , WangJ, IshratT, WeiW, AtifF, SayeedI, SteinDG. Genomic profile of Toll-like receptor pathways in traumatically brain-injured mice: effect of exogenous progesterone. J. Neuroinflammat.8 , 42 (2011).
  • Manley GT , Diaz-ArrastiaR, BrophyM et al. Common data elements for traumatic brain injury: recommendations from the biospecimens and biomarkers working group. Arch. Phys. Med. Rehabil. 91(11) , 1667–1672 (2010).
  • Lupski JR , BelmontJW, BoerwinkleE, GibbsRA. Clan genomics and the complex architecture of human disease. Cell147(1) , 32–43 (2011).
  • Psaty BM , O‘DonnellCJ, GudnasonV et al. Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium: design of prospective meta-analyses of genome-wide association studies from five cohorts. Circ. Cardiovasc. Genet. 2 , 73–80 (2009).
  • The NIH HMP Working Group: The NIH Human Microbiome Project. Genome Res.19(12) , 2317–2323 (2009).
  • Portela A , EstellerM. Epigenetic modifications and human disease. Nat. Biotechnol.28 , 1057–1068 (2010).
  • Gymrek M , McGuireAL, GolanD, HalperinE, ErlichY. Identifying personal genomes by surname inference. Science339(6177) , 321–324 (2013).

▪ Websites

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.