Transdermal Oxycodone Patch For The Treatment of Postherpetic Neuralgia: A Randomized, Double-Blind, Controlled Trial

References

• Chou R , FanciulloGJ , FinePGet al. Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain . J. Pain10 ( 2 ), 113 – 130 ( 2009 ).
   PubMed Web of Science ®Google Scholar
• Fields HL . The doctor’s dilemma: opiate analgesics and chronic pain . Neuron69 ( 4 ), 591 – 594 ( 2011 ).
   PubMed Web of Science ®Google Scholar
• Rosenblum A , MarschLA , JosephH , PortenoyRK . Opioids and the treatment of chronic pain: controversies, current status, and future directions . Exp. Clin. Psychopharmacol.16 ( 5 ), 405 – 416 ( 2008 ).
   PubMed Web of Science ®Google Scholar
• Al-Hasani R , BruchasMR . Molecular mechanisms of opioid receptor-dependent signaling and behavior . Anesthesiology115 ( 6 ), 1363 – 1381 ( 2011 ).
   PubMed Web of Science ®Google Scholar
• Boom M , NiestersM , SartonE , AartsL , SmithTW , DahanA . Non-analgesic effects of opioids: opioid-induced respiratory depression . Curr. Pharm. Des.18 ( 37 ), 5994 – 6004 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Swegle JM , LogemannC . Management of common opioid-induced adverse effects . Am. Fam. Physician74 ( 8 ), 1347 – 1354 ( 2006 ).
   PubMed Web of Science ®Google Scholar
• Nakamura A , HasegawaM , ItoHet al. Distinct relations among plasma concentrations required for different pharmacological effects in oxycodone, morphine, and fentanyl . J. Pain Palliat. Care Pharmacother.25 ( 4 ), 318 – 334 ( 2011 ).
   PubMedGoogle Scholar
• Martin C , De BaerdemaekerA , PoelaertJ , MadderA , HoogenboomR , BalletB . Controlled-release of opioids for improved pain management . Mater. Today29 ( 9 ), 491 – 502 ( 2016 ).
   Google Scholar
• Khansari M , SohrabiM , ZamaniF . The useage of opioids and their adverse effects in gastrointestinal practice: a review . Middle East J. Dig. Dis.5 ( 1 ), 5 – 16 ( 2013 ).
   PubMedGoogle Scholar
• Benyamin R , TrescotAM , DattaSet al. Opioid complications and side effects . Pain Physician11 ( Suppl. 2 ), S105 – S120 ( 2008 ).
   PubMed Web of Science ®Google Scholar
• Moorman-Li R , MotyckaCA , IngeLD , CongdonJM , HobsonS , PokropskiB . A review of abuse-deterrent opioids for chronic nonmalignant pain . PT37 ( 7 ), 412 – 418 ( 2012 ).
   PubMedGoogle Scholar
• Margetts L , SawyerR . Transdermal drug delivery: principles and opioid therapy, continuing education in anaesthesia . Crit. Care Pain7 ( 5 ), ( 2007 ).
   Google Scholar
• Watterson G , HowardR , GoldmanA . Peripheral opioids in inflammatory pain . Arch. Dis. Child.89 ( 7 ), 679 – 681 ( 2004 ).
   PubMed Web of Science ®Google Scholar
• Tennant F , MollD , DepauloV . Topical morphine for peripheral pain . Lancet342 ( 8878 ), 1047 – 1048 ( 1993 ).
   PubMed Web of Science ®Google Scholar
• Zeppetella G , PaulJ , RibeiroMD . Analgesic efficacy of morphine applied topically to painful ulcers . J. Pain Symptom Manage.25 ( 6 ), 555 – 558 ( 2003 ).
   PubMed Web of Science ®Google Scholar
• Smith MT , WyseBD , EdwardsSR , El-TamimyM , GaetanoG , GavinP . Topical application of a novel oxycodone gel formulation (tocopheryl phosphate mixture) in a rat model of peripheral inflammatory pain produces localized pain relief without significant systemic exposure . J. Pharm. Sci.104 ( 7 ), 2388 – 2396 ( 2015 ).
   PubMed Web of Science ®Google Scholar
• Stein C . Targeting pain and inflammation by peripherally acting opioids . Front. Pharmacol.4 , 123 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Stein C , SchaferM , MachelskaH . Attacking pain at its source: new perspectives on opioids . Nat. Med.9 ( 8 ), 1003 – 1008 ( 2003 ).
   PubMed Web of Science ®Google Scholar
• Kapitzke D , VetterI , CabotPJ . Endogenous opioid analgesia in peripheral tissues and the clinical implications for pain control . Ther. Clin. Risk Manag.1 ( 4 ), 279 – 297 ( 2005 ).
   PubMedGoogle Scholar
• Machelska H . Control of neuropathic pain by immune cells and opioids . CNS Neurol. Disord. Drug Targets10 ( 5 ), 559 – 570 ( 2011 ).
   PubMed Web of Science ®Google Scholar
• Machelska H , SteinC . Immune mechanisms in pain control . Anesth. Analg.95 ( 4 ), 1002 – 1008 , table of contents ( 2002 ).
   PubMed Web of Science ®Google Scholar
• Berland D , RodgersP . Rational use of opioids for management of chronic nonterminal pain . Am. Fam. Physician86 ( 3 ), 252 – 258 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Hamunen K , PaakkariP , KalsoE . Trends in opioid consumption in the Nordic countries 2002–2006 . Eur. J. Pain13 ( 9 ), 954 – 962 ( 2009 ).
   PubMed Web of Science ®Google Scholar
• Kalso E . Oxycodone . J. Pain Symptom Manage.29 ( Suppl. 5 ), S47 – S56 ( 2005 ).
   PubMed Web of Science ®Google Scholar
• Schmidt-Hansen M , BennettMI , ArnoldS , BromhamN , HilgartJS . Oxycodone for cancer-related pain . Cochrane Database Syst. Rev.2 , CD003870 ( 2015 ).
   PubMedGoogle Scholar
• Moradi M , EsmaeiliS , ShoarS , SafariS . Use of oxycodone in pain management . Anesth. Pain Med.1 ( 4 ), 262 – 264 ( 2012 ).
   PubMedGoogle Scholar
• Gavin PD , El-TamimyM , KeahHH , BoydBJ . Tocopheryl phosphate mixture (TPM) as a novel lipid-based transdermal drug delivery carrier: formulation and evaluation . Drug Deliv. Transl. Res.7 ( 1 ), 53 – 65 ( 2016 ).
   Web of Science ®Google Scholar
• Jeon YH . Herpes zoster and postherpetic neuralgia: practical consideration for prevention and treatment . Korean J. Pain28 ( 3 ), 177 – 184 ( 2015 ).
   PubMedGoogle Scholar
• Von Hehn CA , BaronR , WoolfCJ . Deconstructing the neuropathic pain phenotype to reveal neural mechanisms . Neuron73 ( 4 ), 638 – 652 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Farrar JT , YoungJP , Jr , LamoreauxL , WerthJL , PooleRM . Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale . Pain94 ( 2 ), 149 – 158 ( 2001 ).
   PubMed Web of Science ®Google Scholar
• Bouhassira D , AttalN , FermanianJet al. Development and validation of the neuropathic pain symptom inventory . Pain108 ( 3 ), 248 – 257 ( 2004 ).
   PubMed Web of Science ®Google Scholar
• Baron R , BinderA , WasnerG . Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment . Lancet Neurol.9 ( 8 ), 807 – 819 ( 2010 ).
   PubMed Web of Science ®Google Scholar
• Sacks GM . Unmet need in the treatment of postherpetic neuralgia . Am. J. Manag. Care19 ( Suppl. 1 ), S207 – S213 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Baron R , ForsterM , BinderA . Subgrouping of patients with neuropathic pain according to pain-related sensory abnormalities: a first step to a stratified treatment approach . Lancet Neurol.11 ( 11 ), 999 – 1005 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Ranoux D , AttalN , MorainF , BouhassiraD . Botulinum toxin type A induces direct analgesic effects in chronic neuropathic pain . Ann. Neurol.64 ( 3 ), 274 – 283 ( 2008 ).
   PubMed Web of Science ®Google Scholar
• Edwards RR , HaythornthwaiteJA , TellaP , MaxMB , RajaS . Basal heat pain thresholds predict opioid analgesia in patients with postherpetic neuralgia . Anesthesiology104 ( 6 ), 1243 – 1248 ( 2006 ).
   PubMed Web of Science ®Google Scholar
• Attal N , RouaudJ , BrasseurL , ChauvinM , BouhassiraD . Systemic lidocaine in pain due to peripheral nerve injury and predictors of response . Neurology62 ( 2 ), 218 – 225 ( 2004 ).
   PubMed Web of Science ®Google Scholar
• Finnerup NB , SindrupSH , BachFW , JohannesenIL , JensenTS . Lamotrigine in spinal cord injury pain: a randomized controlled trial . Pain96 ( 3 ), 375 – 383 ( 2002 ).
   PubMed Web of Science ®Google Scholar
• Simpson DM , SchifittoG , CliffordDBet al. Pregabalin for painful HIV neuropathy: a randomized, double-blind, placebo-controlled trial . Neurology74 ( 5 ), 413 – 420 ( 2010 ).
   PubMed Web of Science ®Google Scholar
• Demant DT , LundK , VollertJet al. The effect of oxcarbazepine in peripheral neuropathic pain depends on pain phenotype: a randomised, double-blind, placebo-controlled phenotype-stratified study . Pain155 ( 11 ), 2263 – 2273 ( 2014 ).
   PubMed Web of Science ®Google Scholar
• Demant DT , LundK , FinnerupNBet al. Pain relief with lidocaine 5% patch in localized peripheral neuropathic pain in relation to pain phenotype: a randomised, double-blind, and placebo-controlled, phenotype panel study . Pain156 ( 11 ), 2234 – 2244 ( 2015 ).
   PubMed Web of Science ®Google Scholar
• Gavin PD , SimonLS , SchlagheckT , SmithAJ , ShakibS . Pharmacokinetics, safety and tolerability of a novel TPM/oxycodone transdermal patch system: a Phase I study . [manuscript submitted] ( 2016 ).
   Google Scholar
• Oxycontin (oxycodone HCl) Controlled-Release Tablets, prescribing information ( 2016 ).
   Google Scholar