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Pain Management Volume 8, 2018 - Issue 2
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Research Article

Qualities of Sore Throat Index (QuaSTI): Measuring Descriptors of Sore Throat in a Randomized, Placebo-Controlled Trial

Bernard Schachtel1 Schachtel Research Company Inc., Jupiter, FL33477, USA;2 Yale School of Public Health, New Haven, CT06520-8034, USAView further author information
,
Adrian Shephard3 Reckitt Benckiser Healthcare International Ltd, 103–105 Bath Road, Slough, BerkshireSL1 3UH, UKCorrespondence[email protected]
View further author information
,
Emily Schachtel1 Schachtel Research Company Inc., Jupiter, FL33477, USAView further author information
,
Mary Beth Lorton1 Schachtel Research Company Inc., Jupiter, FL33477, USAView further author information
,
Tim Shea4 Reckitt Benckiser, Parsippany, NJ07054-0225, USAView further author information
&
Sue Aspley3 Reckitt Benckiser Healthcare International Ltd, 103–105 Bath Road, Slough, BerkshireSL1 3UH, UKView further author information
Pages 85-94 | Received 03 Jul 2017, Accepted 02 Jan 2018, Published online: 30 Jan 2018

References

  • Kenealy T . Sore throat . BMJ Clin. Evid.3 ( 1509 ), PMC3948435 ( 2014 ).
  • Rennie R , CrowsonB . The management of upper respiratory tract infections . J. R. Nav. Med. Serv.99 ( 3 ), 97 – 105 ( 2013 ).
  • Vincent MT , CelestinN , HussainAN . Pharyngitis . Am. Fam. Physician69 ( 6 ), 1465 – 1470 ( 2004 ).
  • Renner B , MuellerCA , ShephardA . Environmental and non-infectious factors in the aetiology of pharyngitis (sore throat) . Inflamm. Res.61 ( 10 ), 1041 – 1052 ( 2012 ).
  • Worrall GJ . Acute sore throat . Can. Fam. Physician53 ( 11 ), 1961 – 1962 ( 2007 ).
  • Shulman ST , BisnoAL , CleggHWet al. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America . Clin. Infect. Dis.55 ( 10 ), E86 – E102 ( 2012 ).
  • Fox K , TurnerJ , FoxA . Role of beta-hemolytic group C streptococci in pharyngitis: incidence and biochemical characteristics of Streptococcus equisimilis and Streptococcus anginosus in patients and healthy controls . J. Clin. Microbiol.31 ( 4 ), 804 – 807 ( 1993 ).
  • Shephard A , SmithG , AspleyS , SchachtelBP . Randomised, double-blind, placebo-controlled studies on flurbiprofen 8.75 mg lozenges in patients with/without group A or C streptococcal throat infection, with an assessment of clinicians’ prediction of ‘strep throat’ . Int. J. Clin. Pract.69 ( 1 ), 59 – 71 ( 2015 ).
  • Tiemstra J , MirandaRL . Role of non-group A streptococci in acute pharyngitis . J. Am. Board Fam. Med.22 ( 6 ), 663 – 669 ( 2009 ).
  • Turner JC , FoxA , FoxKet al. Role of group C beta-hemolytic streptococci in pharyngitis: epidemiologic study of clinical features associated with isolation of group C streptococci . J. Clin. Microbiol.31 ( 4 ), 808 – 811 ( 1993 ).
  • Fink R . Pain assessment: the cornerstone to optimal pain management . Proc. (Bayl. Univ. Med. Cent.)13 ( 3 ), 236 – 239 ( 2000 ).
  • Addey D , ShephardA . Incidence, causes, severity and treatment of throat discomfort: a four-region online questionnaire survey . BMC Ear Nose Throat Disord.12 , 9 ( 2012 ).
  • Schachtel BP , FillingimJM , BeiterDJ , LaneAC , SchwartzLA . Subjective and objective features of sore throat . Arch. Intern. Med.144 ( 3 ), 497 – 500 ( 1984 ).
  • Shephard A . A questionnaire-based study in 12 countries to investigate the drivers of antibiotic-seeking behavior for sore throat . J. Fam. Med. Comm. Health1 ( 3 ), 1014 ( 2014 ).
  • Schachtel BP , AspleyS , BerryPet al. Chief complaint: the therapeutogenic stimulus as the primary, individualized endpoint in clinical trials . J. Pain13 ( 4 ), S6 ( 2012 ).
  • Schachtel BP , AspleyS , ShephardAet al. The Qualities of Sore Throat Index (QuaSTI): first use in a clinical trial testing the effects of flurbiprofen 8.75 mg lozenge on patient-reported qualities of throat pain . Clin. Ther.37 ( 8 ), E94 – E95 ( 2015 ).
  • Schachtel BP , AspleyS , ShephardAet al. Onset of analgesia by a topically administered flurbiprofen lozenge: a randomised controlled trial using the double stopwatch method . Br. J. Pain ( 2018 ) ( In Press ).
  • Schachtel BP , AspleyS , ShephardA , SheaT , SmithG , SchachtelE . Utility of the sore throat pain model in a multiple-dose assessment of the acute analgesic flurbiprofen: a randomized controlled study . Trials15 , 263 ( 2014 ).
  • Schachtel BP , FillingimJM , BeiterDJ , LaneAC , SchwartzLA . Rating scales for analgesics in sore throat . Clin. Pharmacol. Ther.36 ( 2 ), 151 – 156 ( 1984 ).
  • Schachtel BP , HomanHD , GibbIA , ChristianJ . Demonstration of dose response of flurbiprofen lozenges with the sore throat pain model . Clin. Pharmacol. Ther.71 ( 5 ), 375 – 380 ( 2002 ).
  • Aspley S , ShephardA , SchachtelE , SannerK , SavinoL , SchachtelBP . Efficacy of flurbiprofen 8.75 mg lozenge in patients with a swollen and inflamed sore throat . Curr. Med. Res. Opin.32 ( 9 ), 1529 – 1538 ( 2016 ).
  • Schachtel BP , ShephardA , SannerKet al. Long-lasting relief of throat symptoms (throat pain and swollen throat) and throat function (ability to swallow) with flurbiprofen 8.75 mg lozenge . Pain Pract.16 ( Suppl. S1 ), 6 – 176 ( 2016 ).
  • Farrar JT , YoungJPJr , LaMoreauxL , WerthJL , PooleRM . Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale . Pain94 ( 2 ), 149 – 158 ( 2001 ).
  • Chang AK , BijurPE , EssesD , BarnabyDP , BaerJ . Effect of a single dose of oral opioid and nonopioid analgesics on acute extremity pain in the emergency department: a randomized clinical trial . JAMA318 ( 17 ), 1661 – 1667 ( 2017 ).

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