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Perspective

Oral Pain Associated with Cancer Therapy, a Pain Medicine Perspective

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Pages 487-493 | Received 29 May 2018, Accepted 09 Aug 2018, Published online: 09 Nov 2018

References

  • Kwon Y . Mechanism-based management for mucositis: option for treating side effects without compromising the efficacy of cancer therapy . Onco. Targets Ther.9 , 2007 – 2016 ( 2016 ).
  • Avritscher EB , CooksleyCD , EltingLS . Scope and epidemiology of cancer therapy-induced oral and gastrointestinal mucositis . Semin. Oncol. Nurs.20 ( 1 ), 3 – 10 ( 2004 ).
  • Feller L , EssopR , WoodNHet al. Chemotherapy- and radiotherapy-induced oral mucositis: pathobiology, epidemiology and management . SADJ65 ( 8 ), 372 – 374 ( 2010 ).
  • Sonis ST , EltingLS , KeefeDet al. Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients . Cancer100 ( 9 Suppl ), 1995 – 2025 ( 2004 ).
  • Maria OM , EliopoulosN , MuanzaT . Radiation-induced oral mucositis . Front. Oncol.7 , 89 ( 2017 ).
  • Barasch A , PetersonDE . Risk factors for ulcerative oral mucositis in cancer patients: unanswered questions . Oral Oncol.39 ( 2 ), 91 – 100 ( 2003 ).
  • Hahn T , ZhelnovaE , SuchestonLet al. A deletion polymorphism in glutathione-S-transferase mu (GSTM1) and/or θ (GSTT1) is associated with an increased risk of toxicity after autologous blood and marrow transplantation . Biol. Blood Marrow Transplant.16 ( 6 ), 801 – 808 ( 2010 ).
  • Eilers J , MillionR . Clinical update: prevention and management of oral mucositis in patients with cancer . Semin. Oncol. Nurs.27 ( 4 ), e1 – e16 ( 2011 ).
  • Cinausero M , AprileG , ErmacoraPet al. New frontiers in the pathobiology and treatment of cancer regimen-related mucosal injury . Front, Pharmacol.8 , 354 ( 2017 ).
  • Lalla RV , SonisST , PetersonDE . Management of oral mucositis in patients who have cancer . Dent. Clin. N. Am.52 ( 1 ), 61 – 77 ; Lviii ( 2008 ).
  • Quinn B , PottingCMJ , StoneRet al. Guidelines for the assessment of oral mucositis in adult chemotherapy, radiotherapy and haematopoietic stem cell transplant patients . Eur. J. Cancer44 ( 1 ), 61 – 72 ( 2008 ).
  • Lalla RV , BowenJ , BaraschAet al. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy . Cancer120 ( 10 ), 1453 – 1461 ( 2014 ).
  • Epstein JB , SchubertMM . Oropharyngeal mucositis in cancer therapy. Review of pathogenesis, diagnosis, and management . Oncology (Williston Park)17 ( 12 ), 1767 – 1779 ( 2003 ); discussion 1779–1782, 1791–1792 .
  • Rosenberg SW . Oral care of chemotherapy patients . Dent. Clin. N. Am.34 ( 2 ), 239 – 250 ( 1990 ).
  • Devi S , SinghN . Dental care during and after radiotherapy in head and neck cancer . Natl J. Maxillofac. Surg.5 ( 2 ), 117 – 125 ( 2014 ).
  • Schuurhuis JM , StokmanMA , RoodenburgJLet al. Efficacy of routine pre-radiation dental screening and dental follow-up in head and neck oncology patients on intermediate and late radiation effects. A retrospective evaluation . Radiother. Oncol.101 ( 3 ), 403 – 409 ( 2011 ).
  • Tsuji K , ShibuyaY , AkashiMet al. Prospective study of dental intervention for hematopoietic malignancy . J. Dent. Res.94 ( 2 ), 289 – 296 ( 2015 ).
  • Kanuga S . Cryotherapy and keratinocyte growth factor may be beneficial in preventing oral mucositis in patients with cancer, and sucralfate is effective in reducing its severity . J. Am. Dent. Assoc.144 ( 8 ), 928 – 929 ( 2013 ).
  • de Lima AG , VillarRC , de CastroG . Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a Phase III randomized study . Int. J. Radiat. Oncol. Biol. Phys.82 ( 1 ), 270 – 275 ( 2012 ).
  • Jadaud E , BensadounR . Low-level laser therapy: a standard of supportive care for cancer therapy-induced oral mucositis in head and neck cancer patients?Laser Ther.21 ( 4 ), 297 – 303 ( 2012 ).
  • Ferreira B , da Motta SilveiraFM , de OrangeFA . Low-level laser therapy prevents severe oral mucositis in patients submitted to hematopoietic stem cell transplantation: a randomized clinical trial . Support Care Cancer24 ( 3 ), 1035 – 1042 ( 2016 ).
  • Spivakovsky S . Low level laser therapy may reduce risk of oral mucositis . Evid. Based Dent.16 ( 2 ), 49 ( 2015 ).
  • Bensinger W , SchubertM , AngKKet al. NCCN task force report. Prevention and management of mucositis in cancer care . J. Natl Compr. Canc. Netw.6 ( Suppl 1 ), S1 – S21 ( 2008 ); quiz S22–S24 .
  • Alfieri S , RipamondtiCI , MarcegliaSet al. Temporal course and predictive factors of analgesic opioid requirement for chemoradiation-induced oral mucositis in oropharyngeal cancer . Head Neck38 ( Suppl 1 ), E1521 – E1527 ( 2016 ).
  • Coda BA , O’SullivanB , DonaldsonGet al. Comparative efficacy of patient-controlled administration of morphine, hydromorphone, or sufentanil for the treatment of oral mucositis pain following bone marrow transplantation . Pain72 ( 3 ), 333 – 346 ( 1997 ).
  • Epstein JB et al. Oral topical doxepin rinse: analgesic effect in patients with oral mucosal pain due to cancer or cancer therapy . Oral Oncol.37 ( 8 ), 632 – 637 ( 2001 ).
  • Epstein JB , TrueloveEL , OienHet al. Management of pain in cancer patients with oral mucositis: follow-up of multiple doses of doxepin oral rinse . J. Pain Symptom Manage.33 ( 2 ), 111 – 114 ( 2007 ).
  • Epstein JB , TrueloveEL , OienHet al. Oral doxepin rinse: the analgesic effect and duration of pain reduction in patients with oral mucositis due to cancer therapy . Anesth. Analg.103 ( 2 ), 465 – 470 ( 2006 ).
  • Epstein JB , EpsteinJD , EpsteinMS . Doxepin rinse for management of mucositis pain in patients with cancer: one week follow-up of topical therapy . Spec. Care Dentist28 ( 2 ), 73 – 77 ( 2008 ).
  • Leenstra JL , MillerRC , QinRet al. Doxepin rinse versus placebo in the treatment of acute oral mucositis pain in patients receiving head and neck radiotherapy with or without chemotherapy: a Phase III, randomized, double-blind trial . J. Clin. Oncol.32 ( 15 ), 1571 – 1577 ( 2014 ).
  • Ryan AJ , LinF , AtayeeRS . Ketamine mouthwash for mucositis pain . J. Palliat. Med.12 ( 11 ), 989 – 991 ( 2009 ).
  • Mogensen S , SverrisdottirE . Absorption of bupivacaine after administration of a lozenge as topical treatment for pain from oral mucositis . Basic Clin. Pharmacol. Toxicol.120 ( 1 ), 71 – 78 ( 2017 ).
  • Buchsel PC . Polyvinylpyrrolidone-sodium hyaluronate gel (Gelclair): a bioadherent oral gel for the treatment of oral mucositis and other painful oral lesions . Expert Opin. Drug Metab. Toxicol.4 ( 11 ), 1449 – 1454 ( 2008 ).
  • Barber C , PowellR , EllisAet al. Comparing pain control and ability to eat and drink with standard therapy vs Gelclair: a preliminary, double centre, randomised controlled trial on patients with radiotherapy-induced oral mucositis . Support Care Cancer15 ( 4 ), 427 – 440 ( 2007 ).
  • Vokurka S , SkardovaJ , HruskovaR . The effect of polyvinylpyrrolidone-sodium hyaluronate gel (Gelclair) on oral microbial colonization and pain control compared with other rinsing solutions in patients with oral mucositis after allogeneic stem cells transplantation . Med. Sci. Monit.17 ( 10 ), CR572 – CR576 ( 2011 ).
  • Hadjieva T , Cavallin-StahlE , LindenM . Treatment of oral mucositis pain following radiation therapy for head-and-neck cancer using a bioadhesive barrier-forming lipid solution . Support Care Cancer22 ( 6 ), 1557 – 1562 ( 2014 ).
  • Roldan CJ , NouriK , ChaiTet al. Methylene blue for the treatment of intractable pain associated with oral mucositis . Pain Pract.17 ( 8 ), 1115 – 1121 ( 2017 ).

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