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Pain Management Volume 12, 2022 - Issue 6
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Short Communication

Ultrasound-Guided 5% Dextrose Prolotherapy Versus Corticosteroid Injection in Carpal Tunnel Syndrome: A randomized, Controlled Clinical Trial

Arash Babaei-Ghazani1 Neuromusculoskeletal Research Center, Department of Physical Medicine & Rehabilitation, School of Medicine, Iran University of Medical Sciences, Tehran, Iran;2 Department of Physical Medicine & Rehabilitation, University of Montreal Health Center, Montreal, CanadaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3874-9298
ORCID Icon,
Sara Moradnia1 Neuromusculoskeletal Research Center, Department of Physical Medicine & Rehabilitation, School of Medicine, Iran University of Medical Sciences, Tehran, IranORCID Iconhttps://orcid.org/0000-0003-1975-6951
ORCID Icon,
Maziar Azar3 Department of Neurosurgery, Iran University of Medical Sciences, Tehran, IranORCID Iconhttps://orcid.org/0000-0003-4486-4487
ORCID Icon,
Bijan Forogh1 Neuromusculoskeletal Research Center, Department of Physical Medicine & Rehabilitation, School of Medicine, Iran University of Medical Sciences, Tehran, IranORCID Iconhttps://orcid.org/0000-0002-3718-8719
ORCID Icon,
Tannaz Ahadi1 Neuromusculoskeletal Research Center, Department of Physical Medicine & Rehabilitation, School of Medicine, Iran University of Medical Sciences, Tehran, IranORCID Iconhttps://orcid.org/0000-0002-6963-2503
ORCID Icon,
Samira Chaibakhsh1 Neuromusculoskeletal Research Center, Department of Physical Medicine & Rehabilitation, School of Medicine, Iran University of Medical Sciences, Tehran, Iran;4 Eye Research Center, The five Senses Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran1ORCID Iconhttps://orcid.org/0000-0001-9462-118X
ORCID Icon,
Mehrdad Khodabandeh1 Neuromusculoskeletal Research Center, Department of Physical Medicine & Rehabilitation, School of Medicine, Iran University of Medical Sciences, Tehran, IranORCID Iconhttps://orcid.org/0000-0001-5862-587X
ORCID Icon &
Bina Eftekharsadat5 Department of Physical Medicine & Rehabilitation, Physical Medicine & Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, IranORCID Iconhttps://orcid.org/0000-0002-1804-7793
ORCID Icon show all
Pages 687-697 | Received 27 Jan 2022, Accepted 20 Jun 2022, Published online: 18 Jul 2022

References

  • Bongers FJ , SchellevisFG , vanden Bosch WJ , vander Zee J. Carpal tunnel syndrome in general practice (1987 and 2001): incidence and the role of occupational and non-occupational factors. Br. J. Gen. Pract.57(534), 36–39 (2007).
  • Roquelaure Y , ChazelleE , GautierLet al. Time trends in incidence and prevalence of carpal tunnel syndrome over eight years according to multiple data sources: pays de la Loire study. Scand. J. Work Environ. Health43(1), 75–85 (2017).
  • de Krom MC , KnipschildPG , KesterAD , ThijsCT , BoekkooiPF , SpaansF. Carpal tunnel syndrome: prevalence in the general population. J. Clin. Epidemiol.45(4), 373–376 (1992).
  • Aroori S , SpenceRA. Carpal tunnel syndrome. Ulster Med.77(1), 6–17 (2008).
  • Carlson H , ColbertA , FrydlJ , ArnallE , ElliotM , CarlsonN. Current options for nonsurgical management of carpal tunnel syndrome. Int. J. Clin. Rheumtol.5(1), 129–142 (2010).
  • Ren YM , WangXS , WeiZJet al. Efficacy, safety, and cost of surgical versus nonsurgical treatment for carpal tunnel syndrome: a systematic review and meta-analysis. Medicine (Baltimore)95(40), e4857 (2016).
  • Marshall S , TardifG , AshworthN. Local corticosteroid injection for carpal tunnel syndrome. Cochrane Database Syst. Rev.2, CD001554 (2007).
  • Menge TJ , RinkerEB , FanKH , BlockJJ , LeeDH. Carpal tunnel injections: a novel approach based on wrist width. J. Hand Microsurg.8(1), 21–26 (2016).
  • Distel LM , BestTM. Prolotherapy: a clinical review of its role in treating chronic musculoskeletal pain. PM R3(1 Suppl. 6), S78–S81 (2011).
  • Reeves KD , SitRW , RabagoDP. Dextrose prolotherapy: a narrative review of basic science, clinical research, and best treatment recommendations. Phys. Med. Rehabil. Clin. N. Am.27(4), 783–823 (2016).
  • Rabago D , SlattengrenA , ZgierskaA. Prolotherapy in primary care practice. Prim. Care37(1), 65–80 (2010).
  • Wu YT , HoTY , ChouYCet al. Six-month efficacy of perineural dextrose for carpal tunnel syndrome: a prospective, randomized, double-blind, controlled trial. Mayo Clin. Proc.92(8), 1179–1189 (2017).
  • Wu YT , KeMJ , HoTY , LiTY , ShenYP , ChenLC. Randomized double-blinded clinical trial of 5% dextrose versus triamcinolone injection for carpal tunnel syndrome patients. Ann. Neurol.84(4), 601–610 (2018).
  • Shen YP , LiTY , ChouYCet al. Comparison of perineural platelet-rich plasma and dextrose injections for moderate carpal tunnel syndrome: a prospective randomized, single-blind, head-to-head comparative trial. J. Tissue Eng. Regen. Med.13(11), 2009–2017 (2019).
  • Stevens JC . AAEM minimonograph #26: the electrodiagnosis of carpal tunnel syndrome. American Association of Electrodiagnostic Medicine. Muscle Nerve20(12), 1477–1486 (1997).
  • Suresh K . An overview of randomization techniques: an unbiased assessment of outcome in clinical research. J. Hum. Reprod. Sci.4(1), 8–11 (2011).
  • Levine DW , SimmonsBP , KorisMJet al. A self-administered questionnaire for the assessment of severity of symptoms and functional status in carpal tunnel syndrome. J. Bone Joint Surg.75(11), 1585–1592 (1993).
  • Mauermann ML , WatsonJC. A novel treatment for carpal tunnel syndrome?Mayo Clin. Proc.92(8), 1173–1175 (2017).
  • Roomizadeh P , EftekharsadatB , AbediniAet al. Ultrasonographic assessment of carpal tunnel syndrome severity: a systematic review and meta-analysis. Am. J. Phys. Med. Rehabil.98(5), 373–381 (2019).
  • Babaei-Ghazani A , NikbakhtN , ForoghBet al. Comparison between effectiveness of ultrasound-guided corticosteroid injection above versus below the median nerve in mild to moderate carpal tunnel syndrome: a randomized controlled trial. Am. J. Phys. Med. Rehabil.97(6), 407–413 (2018).
  • Oh S , EttemaAM , ZhaoCet al. Dextrose-induced subsynovial connective tissue fibrosis in the rabbit carpal tunnel: a potential model to study carpal tunnel syndrome? Hand (NY) 3(1), 34–40 (2008).
  • Yoshii Y , ZhaoC , SchmelzerJD , LowPA , AnKN , AmadioPC. Effects of multiple injections of hypertonic dextrose in the rabbit carpal tunnel: a potential model of carpal tunnel syndrome development. Hand (NY)9(1), 52–57 (2014).
  • Yoshii Y , ZhaoC , SchmelzerJD , LowPA , AnKN , AmadioPC. The effects of hypertonic dextrose injection on connective tissue and nerve conduction through the rabbit carpal tunnel. Arch. Phys. Med. Rehabil.90(2), 333–339 (2009).

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