Prolongation of spinal duration by escalating doses of intrathecal epinephrine in lower limb arthroplasty

References

• Memtsoudis SG , SunX , ChiuYLet al. Perioperative Comparative Effectiveness of Anesthetic Technique in Orthopedic Patients. Anesthesiology118(5), 1046–1058 (2013).
   PubMed Web of Science ®Google Scholar
• Singh JA , SloanJA. Health-related quality of life in veterans with prevalent total knee arthroplasty and total hip arthroplasty. Rheumatology47(12), 1826–1831 (2008).
   PubMed Web of Science ®Google Scholar
• Yap E , WeiJ , WebbC , NgK , BehrendsM. Neuraxial and general anesthesia for outpatient total joint arthroplasty result in similarly low rates of major perioperative complications: a multicentered cohort study. Reg.Anesth. Pain Med.47(5), 294–300 (2022).
   PubMed Web of Science ®Google Scholar
• Pu X , SunJ ming. General anesthesia vs spinal anesthesia for patients undergoing total-hip arthroplasty: a meta-analysis. Medicine (Baltimore)98(16), e14925 (2019).
   PubMed Web of Science ®Google Scholar
• Memtsoudis SG , CozowiczC , BekerisJet al. Anaesthetic care of patients undergoing primary hip and knee arthroplasty: consensus recommendations from the International Consensus on Anaesthesia-Related Outcomes after Surgery group (ICAROS) based on a systematic review and meta-analysis. Br. J. Anaesth.123(3), 269–287 (2019).
   PubMed Web of Science ®Google Scholar
• Türker G , UÇkunkayaN , YilmazlarA , DemiragB , TokatO. Effects of adding epinephrine plus fentanyl to low-dose lidocaine for spinal anesthesia in outpatient knee arthroscopy: intrathecal epinephrine for outpatient spinal anesthesia. Acta Anaesthesiol. Scand.47(8), 986–992 (2003).
   PubMed Web of Science ®Google Scholar
• Borgeat A , EkatodramisG , SchenkerCA. Postoperative Nausea and Vomiting in Regional Anesthesia. Anesthesiology98(2), 530–547 (2003).
   PubMed Web of Science ®Google Scholar
• Gurbet A , TurkerG , KoseDO , UckunkayaN. Intrathecal epinephrine in combined spinal-epidural analgesia for labor: dose-response relationship for epinephrine added to a local anesthetic-opioid combination. Int. J. Obstet. Anesth.14(2), 121–125 (2005).
   PubMed Web of Science ®Google Scholar
• Ratajczak-Enselme M , EstebeJP , RoseFXet al. Effect of epinephrine on epidural, intrathecal, and plasma pharmacokinetics of ropivacaine and bupivacaine in sheep. Br. J. Anaesth.99(6), 881–890 (2007).
   PubMed Web of Science ®Google Scholar
• Zhan Q , HuangS , GengG , XieY. Comparison of relative potency of intrathecal bupivacaine for motor block in pregnant versus non-pregnant women. Int. J. Obstet. Anesth.20(3), 219–223 (2011).
   PubMed Web of Science ®Google Scholar
• Chambers WA , LittlewoodDG , LoganMR , ScottDB. Effect of added epinephrine on spinal anesthesia with lidocaine. Anesth. Analg.60(6), 417–420 (1981).
   PubMed Web of Science ®Google Scholar
• Leicht CH , CarlsonSA. Prolongation of lidocaine spinal anesthesia with epinephrine and phenylephrine. Anesth. Analg.65(4), 365–369 (1986).
   PubMed Web of Science ®Google Scholar
• Moore DC , ChadwickHS , ReadyLB. Epinephrine prolongs lidocaine spinal: pain in the operative site the most accurate method of determining local anesthetic duration. Anesthesiology67(3), 416–418 (1987).
   PubMed Web of Science ®Google Scholar
• Racle JP , BenkhadraA , PoyJY , GleizalB. Effect of increasing amounts of epinephrine during isobaric bupivacaine spinal anesthesia in elderly patients. Anesth. Analg.66(9), 882–886 (1987).
   PubMed Web of Science ®Google Scholar
• Goyagi T , NishikawaT. The Addition of Epinephrine Enhances Postoperative Analgesia by Intrathecal Morphine. Anesth. Analg.81(3), 508–513 (1995).
   PubMed Web of Science ®Google Scholar
• Acalovschi I , BodoleaC , ManoiuC. Spinal Anesthesia with Meperidine. Effects of Added alpha-Adrenergic Agonists: Epinephrine Versus Clonidine. Anesth. Analg.84(6), 1333–1339 (1997).
   PubMed Web of Science ®Google Scholar
• Kito K , KatoH , ShibataM , AdachiT , NakaoS ichi , MoriK. The Effect of Varied Doses of Epinephrine on Duration of Lidocaine Spinal Anesthesia in the Thoracic and Lumbosacral Dermatomes. Anesth. Analg.86(5), 1018–1022 (1998).
   PubMed Web of Science ®Google Scholar
• Bergeron L , GirardM , DroletP , GrenierY , LeTruong HH , BoucherC. Spinal procaine with and without epinephrine and its relation to transient radicular irritation. Can. J. Anesth.46(9), 846–849 (1999).
   PubMed Web of Science ®Google Scholar
• Vercauteren M . Intrathecal labor analgesia with bupivacaine and sufentanil: the effect of adding 2.25 μg epinephrine. Reg. Anesth. Pain Med.26(5), 473–477 (2001).
   PubMed Web of Science ®Google Scholar
• de Oliveira GS , BalliuB , NaderA , McCarthyRJ. Dose-Ranging Effects of Intrathecal Epinephrine on Anesthesia/Analgesia: A Meta-Analysis and Metaregression of Randomized Controlled Trials. Reg. Anesth. Pain Med.37(4), 423–432 (2012).
   PubMed Web of Science ®Google Scholar
• Tschopp C , TramèrMR , SchneiderA , ZaarourM , EliaN. Benefit and Harm of Adding Epinephrine to a Local Anesthetic for Neuraxial and Locoregional Anesthesia: A Meta-analysis of Randomized Controlled Trials With Trial Sequential Analyses. Anesth. Analg.127(1), 228–239 (2018).
   PubMed Web of Science ®Google Scholar
• Derakhshan P , ImaniF , KoleiniZS , BaratiA. Comparison of Adding Sufentanil and Low-Dose Epinephrine to Bupivacaine in Spinal Anesthesia: A Randomized, Double-Blind, Clinical Trial. Anesthesiol. Pain Med.8(5),e69600 (2018).
   PubMedGoogle Scholar
• Collins JG , KitahataLM , MatsumotoM , HommaE , SuzukawaM. Spinally Administered Epinephrine Suppresses Noxiously Evoked Activity of WDR Neurons in the Dorsal Horn of the Spinal Cord. Anesthesiology60(4), 269–275 (1984).
   PubMed Web of Science ®Google Scholar
• Reddy SV , MaderdrutJL , YakshTL. Spinal cord pharmacology of adrenergic agonist-mediated antinociception. J. Pharmacol. Exp. Ther.213(3), 525–533 (1980).
   PubMed Web of Science ®Google Scholar
• Bonica JJ , AkamatsuTJ , BergesPU , MorikawaK ichi , KennedyWF. Circulatory Effects of Peridural Block. Anesthesiology34(6), 514–522 (1971).
   PubMed Web of Science ®Google Scholar