Aminophylline in Pain and Migraine

References

• GBD 2016 Neurology Collaborators . Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 18, 459–480 (2019).
   PubMed Web of Science ®Google Scholar
• Gupta J , Gaurkar SS . Migraine: an underestimated neurological condition affecting billions. Cureus 14, e28347 (2022).
   PubMed Web of Science ®Google Scholar
• Fried NT , Elliot MB , Oshinsky ML . The role of adenosine signalling in headache: a review. Brain Sci. 7, 30 (2017).
   PubMed Web of Science ®Google Scholar
• Chen D , Willis-Parker M , Lundberg GP . Migraine headache: is it only a neurological disorder? Links between migraine and cardiovascular disorders. Trends Cardiovasc. Med. 7, 424–430 (2020).
   Google Scholar
• Wang Y , Wang Y , Yue G , Zhao Y . Energy metabolism disturbance in migraine: from a mitochondrial point of view. Front Physiol. 14, 1133528 (2023).
   PubMed Web of Science ®Google Scholar
• Sangiorgi S , Mochi M , Riva R et al. Abnormal platelet mitochondrial function in patients affected by migraine with and without aura. Cephalgia 14, 21–23 (1994).
   PubMed Web of Science ®Google Scholar
• Welch KMA , Levine SR , D’Andrea G , Schultz LR , Helpern JA . Preliminary observations on brain energy metabolism in migraine studied by in vivo phosphorous 31 NMR spectroscopy. Neurology 39, 538–541 (1989).
   PubMed Web of Science ®Google Scholar
• Del Moro L , Rota E , Pirovano E , Rainero I . Migraine, brain glucose metabolism and the “neurogenic hypothesis”: a scoping review. J. Pain 23, 1294–1317 (2022).
   PubMed Web of Science ®Google Scholar
• Gross EC , Lisicki M , Fischer D , Sándor PS , Schoenen J . The metabolic face of migraine - from pathophysiology to treatment. Nat. Rev. Neurol. 15, 627–643 (2019).
   PubMed Web of Science ®Google Scholar
• Bohra SK , Achar RR , Chidambaram SB et al. Current perspectives on mitochondrial dysfunction in migraine. Eur. J. Neurosci. 56, 3738–3754 (2022).
   PubMed Web of Science ®Google Scholar
• de Cassya Lopes Neri L , Ferraris C , Catalano G et al. Ketosis and migraine: a systematic review of the literature and meta-analysis. Front. Nutr. 10, 1204700 (2023).
   PubMed Web of Science ®Google Scholar
• Barbiroli B , Montagna P , Cortelli P et al. Abnormal brain and muscle energy metabolism shown by 31 P magnetic resonance spectroscopy in patients affected by migraine with aura. Neurology 42, 1209–1214 (1992).
   PubMed Web of Science ®Google Scholar
• Reyngoudt H , Paemeleire K , Descamps B , De Deene Y , Achten E . P-MRS demonstrates a reduction in high-energy phosphates in the occipital lobe of migraine without aura patients. Cephalalgia 31, 1243–1253 (2011).
   PubMed Web of Science ®Google Scholar
• Hassan SA , Farooque U , Choudhry AS , Pillai B , Sheikh FN . Therapeutic implications of altered energy metabolism in migraine: a state-of-the-art review. Cureus 12, e8571 (2020).
   PubMed Web of Science ®Google Scholar
• Kristoffersen ES , Børte S , Hagen K , Zwart J-A , Winsvold BS . Migraine, obesity and body fat distribution - a population-based study. J. Headache Pain 21, 97 (2020).
   PubMed Web of Science ®Google Scholar
• Hurh K , Jeong SH , Kim SH , Jang S-Y , Park E-C , Jang S-I . Increased risk of all-cause, Alzheimer’s, and vascular dementia in adults with migraine in Korea: a population-based cohort study. J. Headache Pain 23, 108 (2022).
   PubMed Web of Science ®Google Scholar
• Phillips MCL , Deprez LM , Mortimer GMN et al. Randomized crossover trial of a modified ketogenic diet in Alzheimer’s disease. Alzheimers Res. Ther. 13, 51 (2021).
   PubMed Web of Science ®Google Scholar
• Valente M , Garbo R , Filippi F et al. Migraine prevention through ketogenic diet: more than body mass composition changes. J. Clin. Med. 11, 4946 (2022).
   PubMed Web of Science ®Google Scholar
• Bjorness TE , Greene RW . Adenosine and sleep. Curr. Neuropharmacol. 7, 238–245 (2009).
   PubMed Web of Science ®Google Scholar
• Haskó G , Antonioli L , Cronstein BN . Adenosine metabolism, immunity, and joint health. Biochem. Pharmacol. 151, 307–313 (2018).
   PubMed Web of Science ®Google Scholar
• Guieu R , Devaux C , Henry H et al. Adenosine and migraine. Can. J. Neurol. Sci. 25, 55–58 (1998).
   PubMed Web of Science ®Google Scholar
• Liu H , Xia Y . Beneficial and detrimental role of adenosine signalling in diseases and therapy. J. Appl. Physiol. (1985) 119, 1173–1182 (2015).
   PubMed Web of Science ®Google Scholar
• Jung S-M , Peyton L , Essa H , Choi D-S . Adenosine receptors: emerging non-opioids targets for pain medications. Neurobiol. Pain 11, 100087 (2022).
   PubMedGoogle Scholar
• Zylka MJ . Pain-relieving prospects for adenosine receptors and ectonucleotidases. Trends Mol. Med. 17, 188–196 (2011).
   PubMed Web of Science ®Google Scholar
• Luongo L , Guida F , Maione S , Jacobson KA , Salvamini D . Adenosine metabotropic receptors in chronic pain management. Front. Pharmacol. 12, 651038 (2021).
   PubMed Web of Science ®Google Scholar
• Hu X , Adebiyi MG , Luo J et al. Sustained elevated adenosine via ADORA2B promotes chronic pain through neuro-immune interaction. Cell Rep. 16, 106–119 (2016).
   PubMed Web of Science ®Google Scholar
• Thuraiaiyah J , Al-Karagholi MA , Elbahi FA , Zhuang ZA , Ashina M . Adenosine causes short-lasting vasodilatation and headache but not migraine attacks in migraine patients: a randomized clinical trial. Pain 164, 1118–1127 (2023).
   PubMed Web of Science ®Google Scholar
• Djaladat H , Tajik P , Fard SA , Alehashemi S . The effect of aminophylline on renal colic: a randomized double blind controlled trial. South Med. J. 100, 1081–1084 (2007).
   PubMed Web of Science ®Google Scholar
• Sergedahl M , Karelov A . Experimentally induced ischaemic pain in healthy humans is attenuated by the adenosine receptor antagonist theophylline. Acta Physiol. Scand. 180, 301–306 (2004).
   PubMedGoogle Scholar
• Farsani DM , Rafieezadeh A , Nourian N , Mohammadi H , Naghibi K , Saghir K . Evaluating the preventive effect of metoclopramide and aminophylline on pain after deep vitrectomy. Int. J. Physiol. Pathophysiol. Pharmacol. 14, 316–323 (2022).
   PubMedGoogle Scholar
• Barati-Boldaji R , Shojaei-Zarghani S , Mehrabi M , Amini A , Safarpour AR . Post-dural puncture headache prevention and treatment with aminophylline or theophylline: a systematic review and meta-analysis. Anesth. Pain Med. (Seoul) 18, 177–189 (2023).
   PubMedGoogle Scholar
• Akdere H , Burgazli K . The efficiency of intravenous theophylline on the headache which occurs after spinal anesthesia. J. Neurol. Res. 1, 190–192 (2011).
   Google Scholar
• Wu C , Lian Y , Xie N . Aminophylline injection alleviates pain in postdural puncture headache. Pain Med. 16, 2038–2040 (2015).
   PubMed Web of Science ®Google Scholar
• Yıldırım HU , Bakir M , Rumeli Ş . Evaluation of theophylline efficiency in post-dural puncture headache. JARSS. 28, 247–254 (2020).
   Google Scholar
• Matte GG , Barnes DC , Abrams DN . Pharmacologic interventions in nuclear medicine assessment of cardiac perfusion. J. Pharm. Pharm. Sci. 4, 255–262 (2002).
   Web of Science ®Google Scholar
• Kenyon M , Phillips B , DeWit C . Personal observation: intravenous aminophylline treatment for migraine. CJGIM. 7, 129–130 (2012).
   Google Scholar
• Barnes P . Current therapies for asthma: promise and limitations. Chest 111, S17–S26 (1997).
   Web of Science ®Google Scholar
• Barnes P . Theophylline, new perspectives for an old drug. Am. J. Respir. Crit. Care Med. 167, 813–818 (2003).
   PubMed Web of Science ®Google Scholar
• Shaat AM , Abdalgaleil MM . Is theophylline more effective than sumatriptan in the treatment of post-dural puncture headache? A randomized clinical trial. Egypt J. Anaesth. 37, 310–316 (2021).
   Web of Science ®Google Scholar