Bibliography
- Imig JD , HammockBD. Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases. Nat. Rev. Drug Discov.8(10) , 794–805 (2009).
- Ingraham HR , GlessDR, LoYH. Soluble epoxide hydrolase inhibitors and their potential for treatment of multiple pathologic conditions. Curr. Med. Chem.18(4) , 587–603 (2011).
- Schmelzer KR , KubalaL, NewmanJW, KimIH, EiserichJP, HammockBD. Soluble epoxide hydrolase is a therapeutic target for acute inflammation. Proc. Natl Acad. Sci. USA102 , 9772–9777 (2005).
- Schmelzer KR , InceogluB, KubalaL et al. Enhancement of antinociception by coadministration of nonsteroidal anti-inflammatory drugs and soluble epoxide hydrolase inhibitors. Proc. Natl Acad. Sci. USA 103 , 13646–13651 (2006).
- Inceoglu B , JinksSL, SchmelzerKR, WaiteT, KimIH, HammockBD. Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain. Life Sci.79 , 2311–2319 (2006).
- Inceoglu B , JinksSL, UluA et al. Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways. Proc. Natl Acad. Sci. USA 105(48) , 18901–18906 (2008).
- Inceoglu B , WagnerK, SchebbNH et al. Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP. Proc. Natl Acad. Sci. USA 108(12) , 5093–5097 (2011).
- Liu J -Y, Li N, Yang J et al. Metabolic profiling of murine plasma reveals an unexpected biomarker in rofecoxib-mediated cardiovascular events. Proc. Natl Acad. Sci. USA107(39) , 17017–17022 (2010).
- Morisseau CB , InceogluK, Schmelzer H-J et al. Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids. J. Lipid Res.51(12) , 3481–3490 (2010).
- Hwang SH , WagnerKM, MorisseauC et al. Synthesis and structure–activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase. J. Med. Chem. 54 , 3037–3050 (2011).
- Terashvili M , TsengLF, WuHE et al. Antinociception produced by 14,15-epoxyeicosatrienoic acid is mediated by the activation of β-endorphin and met-enkephalin in the rat ventrolateral periaqueductal gray. J. Pharmacol. Exp. Ther. 326(2) , 614–622 (2008).
- Conroy JL , FangC, GuJ et al. Opioids activate brain analgesic circuits through cytochrome P450/epoxygenase signaling. Nat. Neurosci. 13(3) , 284–286 (2010).
- Wagner K , InceogluB, GillSS, HammockBD. Epoxygenated fatty acids and soluble epoxide hydrolase inhibition: novel mediators of pain reduction J. Agric. Food Chem.59(7) , 2816–2824 (2011).