Sex Differences in N-Palmitoylethanolamide Effectiveness in Neuropathic Pain Associated with Lumbosciatalgia

References

• Konstantinou K , DunnKM . Sciatica: review of epidemiological studies and prevalence estimates . Spine33 ( 22 ), 2464 – 2472 ( 2008 ).
   PubMed Web of Science ®Google Scholar
• Weber H , HolmeI , AmlieE . The natural course of acute sciatica with nerve root symptoms in a double-blind placebo-controlled trial evaluating the effect of piroxicam . Spine18 ( 11 ), 1433 – 1438 ( 1993 ).
   PubMed Web of Science ®Google Scholar
• Hagen KB , JamtvedtG , HildeG , WinnemMF . The updated cochrane review of bed rest for low back pain and sciatica . Spine30 ( 5 ), 542 – 546 ( 2005 ).
   PubMed Web of Science ®Google Scholar
• Koes BW , van TulderMW , PeulWC . Diagnosis and treatment of sciatica . BMJ334 ( 7607 ), 1313 – 1317 ( 2007 ).
   PubMedGoogle Scholar
• Kerr D , ZhaoW , LurieJD . What are long-term predictors of outcomes for lumbar disc herniation? A randomized and observational study . Clin. Orthop. Relat. Res. doi:10.1007/s11999-014-3803-7 ( 2014 ) ( Epub ahead of print ).
   Web of Science ®Google Scholar
• Bachur NR , MasekK , MelmonKL , UdenfriendS . Fatty acid amides of ethanolamine in mammial tissues . J. Biol. Chem.240 , 1019 – 1024 ( 1965 ).
   PubMed Web of Science ®Google Scholar
• Mazzari S , CanellaR , PetrelliL , MarcolongoG , LeonA . N-(2-hydroxyethyl)hexadecanamide is orally active in reducing edema formation and inflammatory hyperalgesia by down-modulating mast cell activation . Eur. J. Pharmacol.300 ( 3 ), 227 – 236 ( 1996 ).
   PubMed Web of Science ®Google Scholar
• Berdyshev EV , BoichotE , GermainNet al. Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells . Eur. J. Pharmacol.330 ( 2–3 ), 231 – 240 ( 1997 ).
   PubMed Web of Science ®Google Scholar
• Skaper SD , BurianiA , Dal TosoRet al. The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons . Proc. Natl Acad. Sci. USA93 ( 9 ), 3984 – 3989 ( 1996 ).
   PubMed Web of Science ®Google Scholar
• Guida G , de MartinoM , CantieriLet al. La palmitoiletanolamida (Normast) en el dolor neuropático crónico por lumbociatalgia de tipo compresivo: estudio clínico multicéntrico . Dolor25 ( 1 ), 37 – 42 ( 2010 ).
   Google Scholar
• Morera C , DíazA , GariboFet al. N-Palmitoilethanolamide in the treatment of neuropathic pain associated with lumbosciatica . Pain Manag.2 ( 2 ), 1 – 6 ( 2012 ).
   PubMedGoogle Scholar
• Morera C , IbáñezMA , MartíJCet al. Calidad de vida en pacientes afectos de lumbociática tratados con palmitoiletanolamida (PEA) . Presented at : Congreso Nacional de la Sociedad Española de Rehabilitación y Medicina Física (SERMEF) . Las Palmas, Spain , 15–18 June 2010 .
   Google Scholar
• Morera C , IbáñezMA , MartíJCet al. Palmitoiletanolamida (PEA) en lumbociática en asociación al tratamiento habitual . Presented at : VIII Congreso de la Sociedad Española del Dolor and IX Reunión Ibero-Americana . Madrid, Spain , 26–29 May 2009 .
   Google Scholar
• Morera C . Eficacia y tolerabilidad de palmitoiletanolamida (PEA) en lumbociática . Presented at : XXIV Congreso Nacional de la Sociedad para el Estudio de las Enfermedades del Raquis (GEER) . Santiago de Compostela, Spain , 4–5 June 2010 .
   Google Scholar
• Morera C . Palmitoylethanolamide (PEA) for sciatic pain associated to usual treatment . Presented at : Pain in Europe VII 7th Congress of the Federation of IASP Chapters (EFIC) . Hamburg, Germany , 21–24 September 2011 .
   Google Scholar
• Kalbasi Anaraki D , SianatiS , SadeghiMet al. Modulation by female sex hormones of the cannabinoid-induced catalepsy and analgesia in ovariectomized mice . Eur. J. Pharmacol.31 ( 586 ), 189 – 196 ( 2009 ).
   Google Scholar
• Zogopoulos P , VasileiouI , PatsourisE , TheocharisSE . The role of endocannabinoids in pain modulation . Fundam. Clin. Pharmacol.27 ( 1 ), 64 – 80 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Kaufmann I , SchellingG , EisnerCet al. Anandamide and neutrophil function in patients with fibromyalgia . Psychoneuroendocrinology33 ( 5 ), 676 – 85 ( 2008 ).
   PubMed Web of Science ®Google Scholar
• Bouhassira D , AttalN , AlchaarHet al. Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4) . Pain114 ( 1–2 ), 29 – 36 ( 2005 ).
   PubMed Web of Science ®Google Scholar
• Fairbank JC , PynsentPB . The Oswestry disability index . Spine25 ( 22 ), 2940 – 2952 ( 2000 ).
   PubMed Web of Science ®Google Scholar
• Gandek B , WareJE , AaronsonNKet al. Cross-validation of item selection and scoring for the SF-12 Health Survey in nine countries: results from the IQOLA Project. International quality of life assessment . J. Clin. Epidemiol.51 ( 11 ), 1171 – 1178 ( 1998 ).
   PubMed Web of Science ®Google Scholar
• Luo X , Lynn GeorgeM , KakourasIet al. Reliability, validity, and responsiveness of the short form 12-item survey (SF-12) in patients with back pain . Spine28 ( 15 ), 1739 – 1745 ( 2003 ).
   PubMed Web of Science ®Google Scholar
• Ueda N , YamanakaK , YamamotoS . Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance . J. Biol. Chem.276 ( 38 ), 35552 – 35557 ( 2001 ).
   PubMed Web of Science ®Google Scholar
• Devane WA , HanusL , BreuerAet al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor . Science258 ( 5090 ), 1946 – 1949 ( 1992 ).
   PubMed Web of Science ®Google Scholar
• Calignano A , La RanaG , GiuffridaA , PiomelliD . Control of pain initiation by endogenous cannabinoids . Nature394 ( 6690 ), 277 – 281 ( 1998 ).
   PubMed Web of Science ®Google Scholar