64
Views
0
CrossRef citations to date
0
Altmetric
Special Report

The Challenges and Prospects of Smooth Muscle Tissue Engineering

, ORCID Icon & ORCID Icon
Pages 135-143 | Received 04 Dec 2023, Accepted 16 Feb 2024, Published online: 05 Mar 2024

References

  • Vaduganathan M , MensahGA, TurcoJV, FusterV, RothGA. The global burden of cardiovascular diseases and risk: a compass for future health. J. Am. Coll. Cardiol.80(25), 2361–2371 (2022).
  • Tang HY , ChenAQ, ZhangH, GaoXF, KongXQ, ZhangJJ. Vascular smooth muscle cells phenotypic switching in cardiovascular diseases. Cells11(24), 1–15 (2022).
  • Nicolas J , MagliS, RabbachinL, SampaolesiS, NicotraF, RussoL. 3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate. Biomacromolecules21(6), 1968–1994 (2020).
  • Stevens KR , MurryCE. Human pluripotent stem cell-derived engineered tissues: clinical considerations. Cell Stem Cell22(3), 294–297 (2018).
  • Li N , SanyourH, RemundT, KellyP, HongZ. Vascular extracellular matrix and fibroblasts-coculture directed differentiation of human mesenchymal stem cells toward smooth muscle-like cells for vascular tissue engineering. Mater. Sci. Eng. C Mater. Biol. Appl.93, 61–69 (2018).
  • Harris LJ , AbdollahiH, ZhangP, McilhennyS, TulenkoTN, DimuzioPJ. Differentiation of adult stem cells into smooth muscle for vascular tissue engineering. J. Surg. Res.168(2), 306–314 (2011).
  • Wanjare M , KuoF, GerechtS. Derivation and maturation of synthetic and contractile vascular smooth muscle cells from human pluripotent stem cells. Cardiovasc. Res.97(2), 321–330 (2013).
  • Floren M , BonaniW, DharmarajanA, MottaA, MigliaresiC, TanW. Human mesenchymal stem cells cultured on silk hydrogels with variable stiffness and growth factor differentiate into mature smooth muscle cell phenotype. Acta Biomater.31, 156–166 (2016).
  • Rim NG , YihA, HsiP, WangY, ZhangY, WongJY. Micropatterned cell sheets as structural building blocks for biomimetic vascular patches. Biomaterials181, 126–139 (2018).
  • Swaminathan G , GadepalliV, StoilovI, MechamRP, RaoRR, RamamurthiA. Pro-elastogenic effects of bone marrow mesenchymal stem cell-derived smooth muscle cells on cultured aneurysmal smooth muscle cells. J.Tissue Eng. Regener. Med.11, 679–693 (2017).
  • Fraser JK , WulurI, AlfonsoZ, HedrickMH. Fat tissue: an underappreciated source of stem cells for biotechnology. Trends Biotechnol.24(4), 150–154 (2006).
  • Musiał-Wysocka A , KotM, MajkaM. The pros and cons of mesenchymal stem cell-based therapies. Cell Transplant.28(7), 801–812 (2019).
  • Shen M , QuertermousT, FischbeinMP, WuJC. Generation of vascular smooth muscle cells from induced pluripotent stem cells: methods, applications, and considerations. Circ. Res.128(5), 670–686 (2021).
  • Swaminathan G , StoilovI, BroekelmannT, MechamR, RamamurthiA. Phenotype-based selection of bone marrow mesenchymal stem cell-derived smooth muscle cells for elastic matrix regenerative repair in abdominal aortic aneurysms. J. Tissue Eng. Regen. Med.12(1), e60–e70 (2018).
  • Sivaraman S , HedrickJ, IsmailS, SlavinC, RaoRR. Generation and characterization of human mesenchymal stem cell-derived smooth muscle cells. Int. J. Mol. Sci.22(19), 1–18 (2021).
  • Bashur CA , RaoRR, RamamurthiA. Perspectives on stem cell-based elastic matrix regenerative therapies for abdominal aortic aneurysms. Stem Cells Transl. Med.2(6), 401–408 (2013).
  • Stephenson M , ReichDH, BohelerKR. Induced pluripotent stem cell-derived vascular smooth muscle cells. Vasc. Biol.2(1), R1–R15 (2020).
  • Cao G , XuanX, HuJ, ZhangR, JinH, DongH. How vascular smooth muscle cell phenotype switching contributes to vascular disease. Cell Commun. Signal.20(1), 180 (2022).
  • Liu S , LinZ. Vascular smooth muscle cells mechanosensitive regulators and vascular remodeling. J. Vasc. Res.59(2), 90–113 (2022).
  • Jeong SI , KwonJH, LimJIet al. Mechano-active tissue engineering of vascular smooth muscle using pulsatile perfusion bioreactors and elastic PLCL scaffolds. Biomaterials26(12), 1405–1411 (2005).
  • Steucke KE , TracyPV, HaldES, HallJL, AlfordPW. Vascular smooth muscle cell functional contractility depends on extracellular mechanical properties. J. Biomech.48(12), 3044–3051 (2015).
  • Yarbrough D , GerechtS. Engineering smooth muscle to understand extracellular matrix remodeling and vascular disease. Bioengineering (Basel)9(9), 449:1–15(2022).
  • Rosellini E , BarbaniN, LazzeriL, CasconeMG. Biomimetic and bioactive small diameter tubular scaffolds for vascular tissue engineering. Biomimetics (Basel)7(4), 199:1–19 (2022).
  • Ryan AJ , O’BrienFJ. Insoluble elastin reduces collagen scaffold stiffness, improves viscoelastic properties, and induces a contractile phenotype in smooth muscle cells. Biomaterials73, 296–307 (2015).
  • Shin YC , LeeJH, JinLet al. Stimulated myoblast differentiation on graphene oxide-impregnated PLGA-collagen hybrid fibre matrices. J. Nanobiotechnol.13, 21 (2015).
  • Weekes A , BartnikowskiN, PintoN, JenkinsJ, MeinertC, KleinTJ. Biofabrication of small diameter tissue-engineered vascular grafts. Acta Biomater.138, 92–111 (2022).
  • Jensen LF , BentzonJF, Albarrán-JuárezJ. The phenotypic responses of vascular smooth muscle cells exposed to mechanical cues. Cells10(9), 2209:1–20(2021).
  • Cocciolone AJ , HawesJZ, StaiculescuMC, JohnsonEO, MurshedM, WagenseilJE. Elastin, arterial mechanics, and cardiovascular disease. Am. J. Physiol. Heart Circ. Physiol.315(2), H189–H205 (2018).
  • Kim BS , KimH, GaoG, JangJ, ChoDW. Decellularized extracellular matrix: a step towards the next generation source for bioink manufacturing. Biofabrication9(3), 034104 (2017).
  • Wolf MT , DalyKA, ReingJE, BadylakSF. Biologic scaffold composed of skeletal muscle extracellular matrix. Biomaterials33(10), 2916–2925 (2012).
  • Kwong G , MarquezHA, YangC, WongJY, KottonDN. Generation of a purified iPSC-derived smooth muscle-like population for cell sheet engineering. Stem Cell Reports13(3), 499–514 (2019).
  • Zhu Y , ThakoreAD, FarryJMet al. Collagen-supplemented incubation rapidly augments mechanical property of fibroblast cell sheets. Tissue Eng. Part A27(5–6), 328–335 (2021).
  • Costantini M , TestaS, MozeticPet al. Microfluidic-enhanced 3D bioprinting of aligned myoblast-laden hydrogels leads to functionally organized myofibers in vitro and in vivo. Biomaterials131, 98–110 (2017).
  • Jeon O , LeeY-B, HintonTJ, FeinbergAW, AlsbergE. Cryopresserved cell-laden alginate microgel bioinki for 3D bioprinting of living tissues. Mater. Today Chem.12, 61–70 (2019).
  • Mccormack A , HighleyCB, LeslieNR, MelchelsFPW. 3D printing in suspension baths: keeping the promises of bioprinting afloat. Trends Biotechnol.38(6), 584–593 (2020).
  • Jeon O , BinLee Y, HintonTJ, FeinbergAW, AlsbergE. Cryopreserved cell-laden alginate microgel bioink for 3D bioprinting of living tissues. Mater. Today Chem.12, 61–70 (2019).
  • Zhou X , NowickiM, SunHet al. 3D bioprinting-tunable small-diameter blood vessels with biomimetic biphasic cell layers. ACS Appl. Mater. Interf.12(41), 45904–45915 (2020).
  • Hollister SJ . Porous scaffold design for tissue engineering. Nat. Mater.4(7), 518–524 (2005).
  • Engbers-Buijtenhuijs P , ButtafocoL, PootAAet al. Biological characterisation of vascular grafts cultured in a bioreactor. Biomaterials27(11), 2390–2397 (2006).
  • Zahedmanesh H , LallyC. A multiscale mechanobiological modelling framework using agent-based models and finite element analysis: application to vascular tissue engineering. Biomech. Model Mechanobiol.11(3–4), 363–377 (2012).
  • Armstrong JPK , StevensMM. Emerging technologies for tissue engineering: from gene editing to personalized medicine. Tissue Eng. Part A25(9–10), 688–692 (2019).
  • Zakharova IS , ZhivenMK, SaayaSBet al. Endothelial and smooth muscle cells derived from human cardiac explants demonstrate angiogenic potential and suitable for design of cell-containing vascular grafts. J. Transl. Med.15(1), 54 (2017).
  • Kuznetsov AV , HermannM, SaksV, HengsterP, MargreiterR. The cell-type specificity of mitochondrial dynamics. Int. J. Biochem. Cell Biol.41(10), 1928–1939 (2009).
  • Xia Y , ZhangX, AnP, LuoJ, LuoY. Mitochondrial homeostasis in VSMCs as a central hub in vascular remodeling. Int. J. Mol. Sci.24(4), 3483:1–15(2023).
  • Bakare AB , DanielJ, StabachJet al. Quantifying mitochondrial dynamics in patient fibroblasts with multiple developmental defects and mitochondrial disorders. Int. J. Mol. Sci.22(12), 6263:1–26(2021).
  • Bakare AB , DeanJ, ChenQet al. Evaluating the bioenergetics health index ratio in Leigh syndrome fibroblasts to understand disease severity. Int. J. Mol. Sci.22(19), 10344:1–20(2021).
  • Bakare AB , LesnefskyEJ, IyerS. Leigh syndrome: a tale of two genomes. Front. Physiol.12, 693734 (2021).
  • Bakare AB , MeshrkeyF, LoweBet al. MitoCellPhe reveals mitochondrial morphologies in single fibroblasts and clustered stem cells. Am. J. Physiol. Cell Physiol.321(4), C735–C748 (2021).
  • Chan DC . Mitochondrial dynamics and its involvement in disease. Annu. Rev. Pathol.15, 235–259 (2020).
  • Vásquez-Trincado C , García-CarvajalI, PennanenCet al. Mitochondrial dynamics, mitophagy and cardiovascular disease. J. Physiol.594(3), 509–525 (2016).
  • Wang L , YuT, LeeH, O’BrienDK, SesakiH, YoonY. Decreasing mitochondrial fission diminishes vascular smooth muscle cell migration and ameliorates intimal hyperplasia. Cardiovasc. Res.106(2), 272–283 (2015).
  • Chi C , LiDJ, JiangYJet al. Vascular smooth muscle cell senescence and age-related diseases: state of the art. Biochim. Biophys. Acta Mol. Basis Dis.1865(7), 1810–1821 (2019).
  • Salabei JK , CumminsTD, SinghM, JonesSP, BhatnagarA, HillBG. PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress. Biochem. J.451(3), 375–388 (2013).
  • Wang PW , PangQ, ZhouTet al. Irisin alleviates vascular calcification by inhibiting VSMC osteoblastic transformation and mitochondria dysfunction via AMPK/Drp1 signaling pathway in chronic kidney disease. Atherosclerosis346, 36–45 (2022).
  • James AM , CocheméHM, SmithRA, MurphyMP. Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J. Biol. Chem.280(22), 21295–21312 (2005).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.