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Special Report

Exploring Innovation in Stem Cell and Regenerative Medicine in Japan: The Power of the Consortium-Based Approach

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Pages 467-477 | Published online: 27 Aug 2014

References

  • Carlson BM . Stem Cell Anthology: From Stem Cell Biology, Tissue Engineering, Cloning, Regenerative Medicine and Biology.Academic Press , London, UK(2010 ).
  • National Institutes of Health, Stem Cell Information. http://stemcells.nih.gov  
  • Takahashi K , YamanakaS . Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors . Cell126 , 663 – 676 ( 2006 ).
  • Scott CT , McCormickJB , DeRouenMC , Owen-SmithJ . Democracy derived? New trajectories in pluripotent stem cell research . Cell145 ( 6 ), 820 – 826 ( 2011 ).
  • Watatani K , XieZ , NakatsujiN , SengokuS . Global competencies of regional stem cell research: bibliometrics for investigating and forecasting research trends . Regen. Med.8 ( 5 ), 659 – 668 ( 2013 ).
  • Bubela T , StrotmannA , AdamsR , MorrisonS . Commercialization and collaboration: competing policies in publicly funded stem cell research?Cell Stem Cell7 ( 1 ), 25 – 30 ( 2010 ).
  • Pavitt K . Patent statistics as indicators of innovative activities: possibilities and problems . Scientometrics7 , 77 – 99 ( 1985) .  
  • Mills AE , TereskerzPM . Empirical analysis of major stem cell patent cases: the role of universities . Nat. Biotechnol.28 ( 4 ), 325 – 328 ( 2010 ). 
  • Shibata N , KajikawaY , TakedaY , SakataI , MatsushimaK . Detecting emerging research fronts in regenerative medicine by the citation network analysis of scientific publications . Tech. Forecast. Soc. Change78 ( 2 ), 274 – 282 ( 2011 ).
  • Sengoku S , SumikuraK , OkiT , NakatsujiN . Redefining the concept of standardization for pluripotent stem cells . Stem Cell Rev.7 ( 2 ), 221 – 226 ( 2011 ).
  • Kawakami M , SippD , KatoK . Regulatory impacts on stem cell research in Japan . Cell Stem Cell6 ( 5 ), 415 – 418 ( 2010) .
  • Bloomberg. Abe funds stem cells to help cure Japan wasting disease . www.bloomberg.com/news/2013-09-03/abe-funds-stem-cells-to-help-cure-japan-wasting-disease.html
  • Xie Z , SengokuS . Heterogeneities and patterns of innovations in life sciences sector: the case of stem cells employing patent families data . Presented at: 2013 Proceedings of PICMET ’13: Technology Management for Emerging Technologies.San Jose, CA, USA , 28 July–1 August 2013 .
  • The Stem Cell for Safer Medicine . http://sc4sm.org  
  • The NIH Center for Regenerative Medicine . www.crm.nih.gov
  • Chesbrough H . Open Innovation: The New Imperative for Creating and Profiting from Technology.Harvard Business School Press , Boston, MA, USA ( 2003 ).  
  • Etzkowitz H , LeydesdorffL . The dynamics of innovation: from National Systems and ‘Mode 2’ to a Triple Helix of university–industry–government relations . Res. Policy29 , 109 – 123 ( 2000 ).
  • The Tokyo Women’s Medical University/Waseda University Joint Institution for Advanced Biomedical Sciences. http://twins.twmu.ac.jp/first/gaiyou.html
  • Haraguchi Y , ShimizuT , SasagawaTet al. . Fabrication of functional three-dimensional tissues by stacking cell sheets in vitro . Nat. Protoc.7 ( 5 ), 850 – 858 ( 2012 ).
  • Sekine H , ShimizuT , SakaguchiKet al. . In vitro fabrication of functional three-dimensional tissues with perfusable blood vessels , Nat. Commun.4 , 1399 ( 2013 ).
  • Sakaguchi K , ShimizuT , HoraguchiSet al. . In vitro engineering of vascularized tissue surrogates , Sci. Rep.3 , 1316 ( 2013 ).
  • Sengoku S . A consortium-based approach for open innovation: exploring a unique and optimal model for Japan and stem cell technology . Hitotsubashi Business Review61 ( 3 ), 68 – 84 ( 2013 ).
  • Shimizu T , YamatoM , KikuchiA , OkanoT . Cell sheet engineering for myocardial tissue reconstruction . Biomaterials24 ( 13 ) 2309 – 2316 ( 2003 ).
  • Yamada N , OkanoT , SakaiH , KarikusaF , Sawasaki , SakuraiY . Thermo-responsive polymeric surfaces; control of attachment and detachment of cultured cells . Macromol. Chem. Rapid Commun.11 , 571 – 576 ( 1990 ).
  • Kushida A , YamatoM , KonnoC , KikuchiA , SakuraiY , OkanoT . Temperature-responsive culture dishes allow nonenzymatic harvest of differentiated Madin-Darby canine kidney (MDCK) cell sheets . J. Biomed. Mater. Res.51 ( 2 ), 216 – 223 ( 2000 ).
  • Yamato M , UtsumiM , KushidaA , KonnoC , KikuchiA , OkanoT . Thermo-responsive culture dishes allow the intact harvest of multilayered keratinocyte sheets without dispase by reducing temperature . Tissue Eng.7 ( 4 ), 473 – 480 ( 2001 ).
  • Matsuda N , ShimizuT , YamatoM , OkanoT . Tissue engineering based on cell sheet technology . Adv. Mater.19 ( 20 ), 3089 – 3099 ( 2007 ).
  • Yang J , YamatoM , Shimizu Tet al. . Reconstruction of functional tissues with cell sheet engineering . Biomaterials28 ( 34 ), 5033 – 5043 ( 2007 ).
  • Matsuura K , HaraguchiY , ShimizuT , OkanoT . Cell sheet transplantation for heart tissue repair . J. Control. Release169 ( 3 ), 336 – 340 ( 2013) .
  • Elloumi-Hannachi I , YamatoM , OkanoT . Cell sheet engineering: a unique nanotechnology for scaffold-free tissue reconstruction with clinical applications in regenerative medicine . J. Intern. Med.267 ( 1 ), 54 – 70 ( 2010 ).
  • Nishida K , YamatoM , HayashidaYet al. . Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium . N. Engl. J. Med.351 ( 12 ), 1187 – 1196 ( 2004 ).
  • Burillon C , HuotL , JustinVet al. . Cultured autologous oral mucosal epithelial cell sheet (CAOMECS) transplantation for the treatment of corneal limbal epithelial stem cell deficiency . Invest. Ophthalmol. Vis. Sci.53 ( 3 ), 1325 – 1331 ( 2012 ).
  • Wakao S , KitadaM , KurodaYet al. . Multilineage-differentiating stress-enduring (Muse) cells are a primary source of induced pluripotent stem cells in human fibroblasts . Proc. Natl Acad. Sci. USA10824 ), 9875 – 9880 ( 2011 ).
  • Suemori H , YasuchikaK , HasegawaKet al. . Efficient establishment of human embryonic stem cell lines and long-term maintenance with stable karyotype by enzymatic bulk passage . Biochem. Biophys. Res. Commun.345 ( 3 ), 926 – 932 ( 2006 ).
  • Asai Y , TadaM , OtsujiTG , NakatsujiN . Combination of functional cardiomyocytes derived from human stem cells and a highly-efficient microelectrode array system: an ideal hybrid model assay for drug development . Curr. Stem Cell Res. Ther.5 ( 3 ), 227 – 232 ( 2010 ).
  • Highway Program for Realising Regenerative Medicine . www.jst.go.jp/saisei-nw/highway
  • Hirami Y , OsakadaF , TakahashiKet al. . Generation of retinal cells from mouse and human induced pluripotent stem cells . Neurosci. Lett.458 ( 3 ), 126 – 131 ( 2009 ).
  • Jin ZB , OkamotoS , MandaiM , TakahashiM . Induced pluripotent stem cells for retinal degenerative diseases: a new perspective on the challenges . J Genet.88 ( 4 ), 417 – 24 ( 2009 ).
  • Jin ZB , OkamotoS , XiangP , TakahashiM . Integration-free induced pluripotent stem cells derived from retinitis pigmentosa patient for disease modeling . Stem Cells Transl Med.1 ( 6 ), 503 – 509 ( 2012 ).
  • Bergman K , GraffGD . The global stem cell patent landscape: implications for efficient technology transfer and commercial development . Nat. Biotech.25 ( 4 ), 419 – 424 ( 2007 ).  
  • Taylor CJ , BoltonEM , PocockS , SharplesLD , PedersenRA , BradleyJA . Banking on human embryonic stem cells: estimating the number of donor cell lines needed for HLA matching . Lancet366 ( 9502 ), 2019 – 2025 ( 2005 ). ).
  • Rao MS , AuerbachJM . Estimating human embryonic stem-cell numbers . Lancet367 ( 9511 ), 650 ( 2006 ).
  • Crook JM , HeiD , StaceyG . The International Stem Cell Banking Initiative (ISCBI): raising standards to bank on . In Vitro Cell. Dev. Biol. Anim.46 ( 3–4 ), 169 – 172 ( 2010 ). 
  • Ilic D , StephensonE . Promises and challenges of the first clinical-grade induced pluripotent stem cell bank . Regen. Med.8 ( 2 ), 101 – 102 ( 2013 ).
  • Swann GMP . The Economics of Standardization: Final Report for Standards and Technical Regulations Directorate.University of Manchester Press,Manchester, UK ( 2000 ).
  • Weiss M , CargillC . Consortia in the standards development process . J. Am. Soc. Inf. Sci.43 ( 8 ), 559 – 565 ( 1992 ).
  • Brown P , LauderH . Social capital: critical perspectives . In:Human Capital, Social Capital and Collective Intelligence.BaronS , FieldJ , SchullerT (Eds) . Oxford University Press , Oxford, UK , 226 – 242 ( 2001 ).
  • Boder A . Collective intelligence: a keystone in knowledge management . J. Knowl. Manage.10 ( 1 ), 81 – 93 ( 2006 ).
  • Mason C . Regenerative medicine 2.0 . Regen. Med.2 ( 1 ), 11 – 18 ( 2008 ).
  • Rao MS . Funding translational work in cell-based therapy . Cell Stem Cell9 ( 1 ), 7 – 10 ( 2011 ). 
  • Thomas J . Collaborations in stem cell science . Regen. Med.7 ( Suppl. 6 ), 71 – 72 ( 2012 ).
  • Sipp D . Pay-to-participate funding schemes in human cell and tissue clinical studies . Regen. Med.7 ( Suppl. 6 ), 105 – 111 ( 2012 ).
  • Knoepfler PS . Call for fellowship programs in stem cell-based regenerative and cellular medicine: new stem cell training is essential for physicians . Regen. Med.8 ( 2 ), 223 – 225 ( 2013 ).

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