1
Views
4
CrossRef citations to date
0
Altmetric
Original Article

Decrease in Serum Concentration of 5α-Pregnane-3,20-Dione Prior to Spontaneous Labor

, , &
Pages 467-470 | Received 24 Jun 1987, Accepted 29 Apr 1988, Published online: 03 Aug 2009

References

  • Novy M J, Liggins G C. Role of prostaglandins and thromboxanes in the physiologic control of the uterus and in parturition. Semin krinatol 1980; 445–66
  • Otsuki Y, Yamaji K, Fujita M, Nkagi T, Nnizawa O. Serial plasma oxytocin levels during pregnancy and labor. Acta Obstet Gynecol Scand 1983; 62: 15–18
  • Nagata I, Kato K, Makimura N, et al. Comparison of plasma oxytocin levels during spontaneous labor and labor induced by amniotomy, prostaglandin F2α, and prostaglandin E2. Am J Obstet Gynecol 1983; 147: 259–67
  • Bassett J M, Oxborrow T J, Smith I D, Thorburn G D. The concentration of progesterone in the peripheral plasma of the pregnant ewe. J Endocrinol 1969; 45: 449–57
  • Mikhail G, Noall M W, Allen W M. Progesterone levels in the rabbit ovarian vein blood throughout pregnancy. Endocrinology 1961; 69: 504–9
  • Thorburn G D, Schneider W. The progesterone concentration in the plasma of the goat during the oestrous cycle and pregnancy. J Endocrinol 1972; 52: 23–36
  • Bedford C A, Challis J RG, Harrison F A, Heap R B. The role of oestrogens and progesterone in the onset of parturition in various species. J Reprod Fertil 1972, Suppl: 161
  • Csapo A. The in vivo and in vitro effects of estrogen and progesterone on the myometrium. Mechanism of action of steroid hormones, C A Villee, L L Engel. Pergamon Press, London 1961; 126–146
  • Anderson A BM, Flint A PF, Turnbull A. Mechanism of action of glucocorticoids in induction of ovine parturition: effect on placenta steroid metabolism. J Endocrinol 1975; 6661–70
  • Flint A PF, Kingston E J, Robinson J S, Thorburn G D. Initiation of parturition in the goat: evidence for control by foetal glucocorticoid through activation of placental C21-steroid 17α-hydroxylase. J Endocrinol 1978; 78: 367–78
  • Liggins G C. Initiation of spontaneous labor. Clin Obstetr Gynecol 1983; 26: 47–55
  • Flint APE review. Regulations of placental enzymes. Initiation of parturition, Prevention of prematurity. Fourth Ross Conference on Obstetric Research, P C MacDonald, J C Porter. OH: Ross Laboratories, Columbus 1983; 27
  • Batra S, Bengtsson L P, Grundsell H, Sjöberg N-O. Levels of free and protein-bound progesterone in plasma during late pregnancy. J Clin Endocrinol Metab 1976; 42: 1041–47
  • Milewich L, Gomez-Sanchez, Madden J D, MacDonald P C. Isolation and characterization of 5α-Pregnane-3,20-dione and progesterone in peripheral blood of pregnant women. Measurement throughout pregnancy. Gynecol Invest 1975; 6: 291–306
  • Stoa K F, Bessen A. Identification and quantitation of 5α-pregnanedione in human pregnancy plasma. J Steroid Biochem 1975; 621–25
  • Bäckström T, Landgren S, Zetterlund B, . Effects of ovarian steroid hormones on brain excitability and their relation to epilepsy seizure variation during the menstrual cycle. Advances in Epileptology, R J Porter, et al. Raven Press, New York 1984; 269–77
  • Norberg L, Wahlström G, Bäckström T. The anesthetic potency of 3α-hydroxy-5α-pregnane-20-one and 3α-hydroxy-5β-pregnane-20-one determined with an intravenous EEG-threshold method in male rats. Acta Pharmacol et Toxicol 1987; 61: 42–47
  • Bolander H G, Wahlström G, Norberg L. Reevaluation of pharmaco-kinetic properties of some lipid-soluble barbiturates with an EEG-threshold method. Acta Pharmacol et Toxicol 1984; 54: 33–40
  • Bäckström T, Andersson A, Baird D T, Selstam G. The human corpus luteum secretes 5α-pregnan-3,20 dione. Acta Endocrol 1986; 111: 1–6
  • Sanyal M, Villee C. Production and physiologic effects of progesterone metabolites in pregnant and pseudopregnant rats. Endocrinol 1973; 92: 83–93
  • Glasser S, Northcutt R, Chytil F, Strott C. The influence of an antisteriodogenic drug (aminoglutethimide phosphate) on pregnancy maintenance. Endocrinol 1972; 90: 1363–1369
  • Rahman S S, Billiar R B, Little M. Induction of uteroglobin in rabbits by progestagens, estradiol 178 and ACTH. Biol Reprod 1975; 12: 305–14
  • Milewich L, Smith S L, MacDonald. Nonrespiratory functions of the human lung: In vitro metabolism of tritium-labeled progesterone and pregnenolone. J Clin Endocrinol Metab 1980; 50: 507–15
  • Milewich L, Grant N F, Schwarz B E, et al. Progesterone metabolism by placentas of early and late human gestation. Obstet Gynecol 1978; 51: 278–80
  • Milewich L, Grant N F, Schwarz B E, et al. Identification and quantification of progesterone metabolites produced by components of human fetal membranes. J Clin Endocrinol Metab 1977; 45: 400–11
  • Schwartz B E, Milewich L, Grant N F, Porter J C, Johnston J M, MacDonald P C. Progesterone binding and metabolism in human fetal membranes. Ann NY Acad Sci 1977; 286: 304–12
  • Saitoh H, Hirato K, Yanaihara T, Nakayama T. A study of 5α-reductase in human fetal brain. Endocrinol Japan 1982; 29: 461–67

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.