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Original Article

Immunohistochemical studies of organic anion transporters and urate transporter 1 expression in human salivary gland

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Pages 312-316 | Received 08 Aug 2011, Accepted 13 Feb 2012, Published online: 08 May 2012

References

  • Richette P, Bardin T. Gout. Lancet 2010;375:318–28.
  • So A. Developments in the scientific and clinical understanding of gout. Arthritis Res Ther 2008;10:221–6.
  • Mount DB. Molecular physiology and the four-component model of renal urate transport. Curr Opin Nephrol Hypertens 2005;14:460–3.
  • Nigam SK, Bush KT, Bhatnagar V. Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues. Nat Clin Pract Nephrol 2007;3:443–8.
  • Enomoto A, Endou H. Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease. Clin Exp Nephrol 2005;9:195–205.
  • Ahn SY, Nigam SK. Toward a systems level understanding of organic anion and other multispecific drug transporters: a remote sensing and signaling hypothesis. Mol Pharmacol 2009;76:481–90.
  • Bahn A, Hagous Y, Reuter S, Balen D, Brzica H, Kric W, Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13). J Biol Chem 2008;283:16332–41.
  • Sekine T, Cha SH, Endou H. The multispecific organic anion transporter (OAT) family. Pfugers Arch 2000;440:337–50.
  • Kunishima C, Inoue I, Oikawa T, Nakajima H, Komada T, Katayama S. Activating effect of Benzbromarone, a uricosuric drug, on peroxisome proliferators-activated resceptors. PPAR Res 2007:2007;1–5.
  • Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Ho Cha S, Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature 2002;17:447–52.
  • Iwanaga T, Kobayashi D, Hirayama M, Tamai I. Involvement of uric acid transporter in increased renal clearance of the xanthine oxidase inhibitor oxypurinol induced by a uricosuric agent, benzbromarone. Drug Metab Dispos 2005;33:1791–5.
  • El-Sheikh AA, van den Heuvel JJ, Koenderink JB, Russel FG. Effect of hypouricemic and hyperuricemic drugs on the renal urate efflux transporter, multidrug resistance protein 4. Br J Pharmacol 2008;155:1066–75.
  • Imaoka T, Kusuhara H, Adachi-Akahane S, Hasegawa M, Morita N, Endou H, The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules. J Am Soc Nephrol 2004;15:2012–22.
  • Shin HJ, Takeda M, Enomoto A, Fujimura M, Miyazaki H, Anzai N, Interactions of urate transporter URAT1 in human kidney with uricosuric drugs. Nephrology 2011;16:156–62.
  • Hagos Y. Human renal organic anion transporters 4 operates as an asymmetric urate transporter. J Am Soc Nephrol 2007;18:430–9.
  • Shibasaki K, Kimura M, Ikarashi R, Yamaguchi A, Watanabe T. Uric acid concentration in saliva and its changes with the patients receiving treatment for hyperuricemia. Metabolomics 2011; doi:10.1007/s11306-011-0334-z; online published.
  • Enomoto A, Niwa T. Roles of organic anion transporters in the progression of chronic renal failure. Ther Apher Dial 2007;11:27–31.
  • Saito H. Pathophysiological regulation of renal SLC22A organic ion transporters in acute kidney injury: pharmacological and toxicological implications. Pharmacol Ther 2010;125:79–91.
  • Hwang JS, Park EY, Kim WY, Yang CW, Kim J. Expression of OAT1 and OAT3 in differentiating proximal tubules of the mouse kidney. Histol Histopathol 2010;25:33–44.
  • Price KL, Sautin YY, Long DA, Zhang L, Miyazaki H, Mu W, human vascular smooth muscle cells express a urate transporter. J Am Soc Nephrol 2006;17:1791–5.
  • Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus. J Biol Chem 2004;279:45942–50.
  • Hagous Y, Bahn A, Vormefelde SV, Brockmöller J, Burckhardt G. Torasemide transport by organic anion transporters contributes to hyperuricemia. J Am Soc Nephrol 2007;18:3101–9.
  • Hediger MA, Johnson RJ, Miyazaki H, Endou H. Molecular physiology of urate transport. Physiology (Bethesda) 2005;20:125–33.
  • Zhang R, Yang X, Li J, Wu J, Peng WX, Dong XQ, Upregulation of rat renal cortical organic anion transporter (OAT1 and OAT3) expression in response to ischemia/reperfusion injury. Am J Nephrol 2008;8:772–83.
  • Saito M, Mamada H, Anzai N, Shirasaka Y, Nakanishi T, Tamai I. Renal secretion of uric acid by Organic Anion Transporter 2. Biol Pharm Bull 2010;33:498–503.
  • Matsuo H, Chiba T, Nagamori A, Domoto H, Phetdee K, Wiriyasermkul P, Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia. Am J Hum Genet 2008;83:744–51.
  • Anzai N, Ichida K, Jutabha P, Kimura T, Babu E, Jin CJ, Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in human. J Biol Chem 2008;238:26834–8.
  • Matsuo H, Takada T, Ichida K, Nakamura T, Nakayama A, Ikebuchi Y, Common defects of ABCG2, a high-capacity urate exporter, cause gout. Sci Transl Med 2009;1:5ra11.