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Original Article

Expression of Wnt3a, Wnt10b, β-catenin and DKK1 in periodontium during orthodontic tooth movement in rats

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Pages 217-223 | Received 31 Jan 2015, Accepted 30 Aug 2015, Published online: 28 Sep 2015

References

  • Melsen B. Biological reaction of alveolar bone to orthodontic tooth movement. Angle Orthod 1999;69:151–8.
  • Garlet TP, Coelho U, Silva JS, Garlet GP. Cytokine expression pattern in compression and tension sites of the periodontal ligament during orthodontic tooth movement in humans. Eur J Oral Sci 2007;115:355–62.
  • Pavlin D, Dove SB, Zadro R, Gluhak-Heinrich J. Mechanical loading stimulates differentiation of periodontal osteoblasts in a mouse osteoinduction model: effect on type I collagen and alkaline phosphatase genes. Calcif Tissue Int 2000;67:163–72.
  • Kanzaki H, Chiba M, Takahashi I, Haruyama N, Nishimura M, Mitani H. Local OPG gene transfer to periodontal tissue inhibits orthodontic tooth movement. J Dent Res 2004;83:920–5.
  • Kanzaki H, Chiba M, Arai K, Takahashi I, Haruyama N, Nishimura M, et al. Local RANKL gene transfer to the periodontal tissue accelerates orthodontic tooth movement. Gene Ther 2006;13:678–85.
  • Grant M, Wilson J, Rock P, Chapple I. Induction of cytokines, MMP9, TIMPs, RANKL and OPG during orthodontic tooth movement. Eur J Orthod 2013;35:644–51.
  • Zhang MM, Feng DF, Shao P, Sun TT, Wang L, Yang BF. Nifedipine regulated periodontal ligament remodeling: an experimental study in rats. Acta Odontol Scand 2008;66:327–33.
  • Robinson JA, Chatterjee-Kishore M, Yaworsky PJ, Cullen DM, Zhao W, Li C, et al. Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone. J Biol Chem 2006;281:31720–8.
  • Armstrong VJ, Muzylak M, Sunters A, Zaman G, Saxon LK, Price JS, et al. Wnt/betacatenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor alpha. J Biol Chem 2007;282:20715–27.
  • Tang Y, Zhou X, Gao B, Xu X, Sun J, Cheng L, et al. Modulation of Wnt/β-catenin signaling attenuates periapical bone lesions. J Dent Res 2014;93:175–82.
  • Bennett CN, Ouyang H, Ma YL, Zeng Q, Gerin I, Sousa KM, et al. Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation. J Bone Miner Res 2007;22:1924–32.
  • Lim WH, Liu B, Cheng D, Williams BO, Mah SJ, Helms JA. Wnt signaling regulates homeostasis of the periodontal ligament. J. Periodont. Res. 2014;49:751–9.
  • Lim WH, Liu B, Mah SJ, Yin X, Helms JA. Alveolar Bone Turnover and Periodontal Ligament Width are Controlled by Wnt. J Periodontol 2015;86:319–26.
  • Heo JS, Lee SY, Lee JC. Wnt/beta-catenin signaling enhances osteoblastogenic differentiation from human periodontal ligament fibroblasts. Mol Cells 2010;30:449–54.
  • Alhashimi N, Frithiof L, Brudvik P, Bakhiet M. CD40-CD40L expression during orthodontic tooth movement in rats. Angle Orthod 2004;74:100–5.
  • Tan L, Ren Y, Wang J, Jiang L, Cheng H, Sandham A, et al. Osteoprotegerin and ligand of receptor activator of nuclear factor kappaB expression in ovariectomized rats during tooth movement. Angle Orthod 2009;79:292–8.
  • Rooker SM, Liu B, Helms JA. Role of Wnt signaling in the biology of the periodontium. Dev Dyn 2010;239:140–7.
  • Glass DA, Karsenty G. 2nd Canonical Wnt signaling in osteoblasts is required for osteoclast differentiation. Ann N Y Acad Sci 2006;1068:117–30.
  • Megat Abdul Wahab R, Md Dasor M, Senafi S, Abang Abdullah AA, Yamamoto Z, Jemain AA, et al. Crevicular Alkaline Phosphatase Activity and Rate of Tooth Movement of Female Orthodontic Subjects under Different Continuous Force Applications. Int J Dent. 2013;2013:245818
  • Nagai M, Yoshida A, Sato N, Wong DT. Messenger RNA level and protein localization of transforming growth factor-beta1 in experimental tooth movement in rats. Eur J Oral Sci 1999;107:475–81.
  • Boland GM, Perkins G, Hall DJ, Tuan RS. Wnt 3a promotes proliferation and suppresses osteogenic differentiation of adult human mesenchymal stem cells. J Cell Biochem 2004;93:1210–30.
  • Ota K, Quint P, Ruan M, Pederson L, Westendorf JJ, Khosla S, et al. TGF-β induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts. Endocrinology 2013;154:3745–52.
  • Kim-Weroha NA, Ferris A, Holladay B, Kotha SP, Kamel MA, Johnson ML. In vivo load activated propagation of β-catenin signaling in osteocytes through coordinated downregulation of inhibitors of Lrp5. J Bone Miner Res 2008;23:S13
  • Vinyoles M, Del Valle-Pérez B, Curto J, Viñas-Castells R, Alba-Castellón L, García de Herreros A. Multivesicular GSK3 sequestration upon Wnt signaling is controlled by p120-catenin/cadherin interaction with LRP5/6. Mol Cell 2014;53:444–57.
  • Hu H, Hilton MJ, Tu X, Yu K, Ornitz DM, Long F. Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Development 2005;132:49–60.
  • Premaraj S, Souza I, Premaraj T. Mechanical loading activates β-catenin signaling in periodontal ligament cells. Angle Orthod 2011;81:592–9.
  • Bafico A, Liu G, Yaniv A, Gazit A, Aaronson SA. (2001). Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat Cell Biol 2001;3:683–6.
  • Shiotani A, Shibasaki Y, Sasaki T. Localization of receptor activator of NFkappaB ligand, RANKL, in periodontal tissues during experimental movement of rat molars. J Electron Microsc (Tokyo) 2001;50:365–9.
  • Fujita K, Janz S. Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF. Mol Cancer 2007;6:71
  • Napimoga MH, Nametala C, da Silva FL, Miranda TS, Bossonaro JP, Demasi AP, et al. Involvement of the Wnt-β-catenin signalling antagonists, sclerostin and dickkopf-related protein 1, in chronic periodontitis. J Clin Periodontol 2014;41:550–7.
  • Niida A, Hiroko T, Kasai M, Furukawa Y, Nakamura Y, Suzuki Y, et al. DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway. Oncogene 2004;23:8520–6.
  • Kalajzic Z, Peluso EB, Utreja A, Dyment N, Nihara J, Xu M, et al. Effect of cyclical forces on the periodontal ligament and alveolar bone remodeling during orthodontic tooth movement. Angle Orthod 2014;84:297–303.

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