‘Plain lignocaine’ vs ‘Lignocaine with vasoconstrictor’—Comparative evaluation of pain during administration and post-extraction wound healing by a double blinded randomized controlled clinical trial

References

• Milgrom P, Coldwell SE, Getz T, et al. Four dimensions of fear of dental injections. J Am Dent Assoc. 1997;128:756–766.
   PubMed Web of Science ®Google Scholar
• Van Wijk AJ, Hoogstraten J. Anxiety and pain during dental injections. J Dent. 2009;37:700–704.
   PubMed Web of Science ®Google Scholar
• Nusstein JM, Beck M. Effectiveness of 20% benzocaine as a topical anesthetic for intraoral injections. Anesth Prog. 2003;50:159–163.
   PubMedGoogle Scholar
• Shahidi Bonjar AH. Syringe micro vibrator (SMV) a new device being introduced in dentistry to alleviate pain and anxiety of intraoral injections, and a comparative study with a similar device. Ann Surg Innov Res. 2011;5:1. doi:10.1186/1750-1164-5-1.
   PubMedGoogle Scholar
• Kaufman E, Epstein JB, Gorsky M, et al. Preemptive analgesia and local anesthesia as a supplement to general anesthesia: a review. Anesth Prog. 2005;52:29–38.
   PubMedGoogle Scholar
• Lathwal G, Pandit IK, Gugnani N, et al. Efficacy of different precooling agents and topical anesthetics on the pain perception during intraoral injection: a comparative clinical study. Int J Clin Pediatr Dent. 2015;8:118–122.
   Google Scholar
• Heaton LJ, Leroux BG, Ruff PA, et al. Computerized dental injection fear treatment: a randomized clinical trial. J Dent Res. 2013;92:S37–S42.
   PubMed Web of Science ®Google Scholar
• Wilson KE, Welbury RR, Girdler NM. A study of the effectiveness of oral midazolam sedation for orthodontic extraction of permanent teeth in children: a prospective, randomised, controlled, crossover trial. Br Dent J. 2002;192:457–462.
   PubMed Web of Science ®Google Scholar
• Vermeulen M, Vinckier F, Vandenbroucke J. Dental general anesthesia: clinical characteristics of 933 patients. ASDC J Dent Child. 1991;58:27–30.
   PubMed Web of Science ®Google Scholar
• Malamed SF. Handbook of local anesthesia. 6th ed. St. Louis, Missouri: Elsevier; 2013:39.
   Google Scholar
• Brown RS, Rhodus NL. Epinephrine and local anesthesia revisited. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100:401–408.
   PubMed Web of Science ®Google Scholar
• Pérusse R, Goulet JP, Turcotte JY. Contraindications to vasoconstrictors in dentistry: Part I. Cardiovascular diseases. Oral Surg Oral Med Oral Pathol. 1992;74:679–686.
   PubMedGoogle Scholar
• Pérusse R, Goulet JP, Turcotte JY. Contraindications to vasoconstrictors in dentistry: Part II. Hyperthyroidism, diabetes, sulfite sensitivity, cortico-dependent asthma, and pheochromocytoma. Oral Surg Oral Med Oral Pathol. 1992;74:687–691.
   PubMedGoogle Scholar
• Seng GF, Gay BJ. Dangers of sulfites in dental local anesthetic solutions: warning and recommendations. J Am Dent Assoc. 1986;113:769–770.
   PubMed Web of Science ®Google Scholar
• Malamed SF. Handbook of Local Anesthesia. 6th ed. St. Louis, Missouri: Elsevier; 2013:190.
   Google Scholar
• Malamed SF. Handbook of local anesthesia. 6th ed. St. Louis, Missouri: Elsevier; 2013:250.
   Google Scholar
• Malamed SF. Handbook of local anesthesia. 6th ed. St. Louis, Missouri: Elsevier; 2013:211.
   Google Scholar
• Malamed SF. Handbook of local anesthesia. 6th ed. St. Louis, Missouri: Elsevier; 2013:248.
   Google Scholar
• Krebs EE, Carey TS, Weinberger M. Accuracy of the pain numeric rating scale as a screening test in primary care. J Gen Intern Med. 2007;22:1453–1458.
   PubMed Web of Science ®Google Scholar
• Landry RG, Turnbell RS, Howley T. Effectiveness of benzydamine HCL in the treatment of periodontal post-surgical patients. Res Clinic Forums. 1988;10:105–118.
   Google Scholar
• Malamed SF. Handbook of Local Anesthesia, 6th ed. St. Louis, Missouri: Elsevier; 2013:93.
   Google Scholar
• Malamed SF. Handbook of Local Anesthesia. 6th ed. St. Louis, Missouri: Elsevier; 2013:257.
   Google Scholar
• Davies RJ. Buffering the pain of local anaesthetics: a systematic review. Emerg Med (Fremantle). 2003;15:81–88.
   PubMedGoogle Scholar
• Sever C, Kulahci Y, Acar A, et al. Unusual hand frostbite caused by refrigerant liquids and gases. Ulus Travma Acil Cerrahi Derg. 2010;16:433–438.
   PubMed Web of Science ®Google Scholar
• Meechan JG, Day PF. A comparison of intraoral injection discomfort produced by plain and epinephrine-containing lidocaine local anesthetic solutions: a randomized, double-blind, split-mouth, volunteer investigation. Anesth Prog. 2002;49:44–48.
   PubMedGoogle Scholar
• Hille B. The pH-dependent rate of action of local anesthetics on the node of Ranvier. J Gen Physiol. 1977;69:475–496.
   PubMed Web of Science ®Google Scholar
• Malamed SF. Handbook of local anesthesia. 6th ed. St. Louis, Missouri: Elsevier; 2013:277.
   Google Scholar
• Sveen K. Effect of the addition of a vasoconstrictor to local anesthetic solution on operative and postoperative bleeding, analgesia and wound healing. Int J Oral Surg. 1979;8:301–306.
   PubMedGoogle Scholar
• Malamed SF. Handbook of local anesthesia. 6th ed. St. Louis, Missouri: Elsevier; 2013:43.
   Google Scholar
• Meechan JG, Venchard GR, Rogers SN, et al. Local anaesthesia and dry socket. A clinical investigation of single extractions in male patients. Int J Oral Maxillofac Surg. 1987;16:279–284.
   PubMed Web of Science ®Google Scholar
• Howe GL. Minor oral surgery. 3rd ed. Linacre House, Jordan Hill, 1985:92;124.
   Google Scholar
• College C, Feigal R, Wandera A, et al. Bilateral versus unilateral mandibular block anesthesia in a pediatric population. Pediatr Dent. 2000;22:453–457.
   PubMedGoogle Scholar
• Chi D, Kanellis M, Himadi E, et al. Lip biting in a pediatric dental patient after dental local anesthesia: a case report. J Pediatr Nurs. 2008;23:490–493.
   PubMedGoogle Scholar
• Malamed SF. Handbook of local anesthesia. 6th ed. St. Louis, Missouri: Elsevier; 2013:61.
   Google Scholar