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Acta Oto-Laryngologica Volume 75, 1973 - Issue 2-6
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Original Article

The Effects Of Ethacrynic Acid Upon The Cochlear Endolymph And Stria Vascularis: A Preliminary Report

S. K. Bosher Ferens Institute of Otolaryngology, Middlesex Hospital Medical School, University of London, London, England
,
C. Smith Ferens Institute of Otolaryngology, Middlesex Hospital Medical School, University of London, London, England
&
R. L. Warren Ferens Institute of Otolaryngology, Middlesex Hospital Medical School, University of London, London, England
Pages 184-191 | Published online: 08 Jul 2009

References

  • Bosher S. K., Warren R. L. Observations on the electrochemistry of the cochlear endolymph of the rat: a quantitative study of its electrical potential and ionic composition as determined by means of flame spectrophotometry. Proc Roy Soc Biol 1968; 171: 227
  • Bosher S. K., Warren R. L. A study of the electrochemistry and osmotic relationships of the cochlear fluids in the neonatal rat at the time of the development of the endocochlear potential. J Physiol (Lond.) 1971; 212: 139
  • Cohn E. S., Gordes E. H., Brusilow S. W. Ethacrynic acid effect on the composition of cochlear fluids. Science 1971; 171: 910
  • Johnstone B. M. The relation between endolymph and the endocochlear potential during anoxia. Acta Otolaryng (Stockh.) 1965; 60: 113
  • Konishi T., Mendelsohn M. Effect of ouabain on cochlear potentials and endolymph composition in guinea pigs. Acta Otolaryng (Stockh.) 1970; 69: 192
  • Kuijpers W., Bonting S. L. The cochlear potentials. I. The effect of ouabain on the cochlear potentials of the guinea pig. Pfluegers Arch Ges Physiol 1970a; 320: 348
  • Kuijpers W., Bonting S. L. The cochlear potentials. II. The nature of the cochlear endolymphatic resting potential. Pfluegers Arch Ges Physiol 1970b; 320: 359
  • Mathog R. H., Thomas W. G., Hudson W. R. Ototoxicity of new and potent diuretics. Arch Ofolaryng (Chic.) 1970; 92: 7
  • Matz J. M., Beal D. D., Krames L. Ototoxicity of ethacrynic acid. Arch Otolaryng (Chic.) 1969; 90: 152
  • Nakai Y. Electronmicroscopic study of the inner ear after ethacrynic acid intoxication. Pract Otorhinolaryng (Basel) 1971; 33: 366
  • Prazma J., Thomas W. G., Fischer N. D., Preslar J. M. J. Ototoxicity of the ethacrynic acid. Arch Otolaryng (Chic.) 1972; 95: 448
  • Quick C. A., Duvall A. J. Early changes in the cochlear duct from ethacrynic acid. Laryngoscope 1970; 80: 954
  • Silverstein H., Yules R. B. The effect of diuretics on cochlear petentials and inner ear fluids. Laryxgoscope 1971; 81: 873

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