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Original Article

Cochlear Damage from Chlorhexidine in Guinea Pigs

Pages 259-271 | Received 08 Sep 1978, Published online: 08 Jul 2009

References

  • Ansel H. C. Hemolysis of erythrocytes by antibacterial preservatives IV. J Pharm Sci 1967; 56: 616
  • Ballantyne J. Iatrogenic deafness. J Laryngol Otol 1970; 84: 967
  • Bicknell P. G. Sensorineural deafness following myringoplasty operations. J Laryngol Otol 1971; 85: 957
  • Brinemark P. I., Albrektsson B., Lindstrom J., Lundborg G. Local tissue effects of wound disinfectants. Acta Chir Scand 1966; 357: 166, Suppl
  • Davies G. E., Francis J., Martin A. R., Rose F. L., Swain G. 1 :6-di-4′-chlorophenyldiguanido-hexane (“Hibitane”). Laboratory investigation of a new antibacterial agent of high potency. Brit J Pharmacol 1954; 9: 192
  • Duvall A. J., Wersäll J. Site of action of streptomycin upon inner ear sensory cells. Acta Otolaryngol (Stockh.) 1964; 57: 581
  • Engström H., Ades H. W., Andersson A. Structural Patterns of the Organ of Corti. Almqvist & Wiksell, Uppsala 1966
  • Engström H., Kohonen A. Cochlear damage from ototoxic antibiotics. Acta Otolaryngol (Stockh.) 1965; 59: 171
  • Foulkes D. M. Some toxicological observations on chlorhexidine. J Periodont Res 1973; 8(Suppl. 12)55
  • Haug H. P., Giebel W., Breuniger H. Die Ausbreitung von Tetracyclin im Innenohr nach unter-schiedlicher Applikation im Mittelohr. Arch Oto Rhino Lunngol 1978; 218: 229
  • Hawkins J. E., Jr. Drug ototoxicity. Handhook of Sensory Physiology, Vol. V/3. Auditory System. Clinicul cind special topics, W. D. Keidel, W. D. Neff. Springer Verlag, Berlin-Heidelberg-New York 1976; 707–748
  • Hawkins J. E., Jr, Engstrüom H. Effect of kanamycin on cochlear cytoarchitecture. Acta Otolaryngol (Stockh.) 1964; 188: 100, Suppl
  • Hennebert D., Fernández C. Ototoxicity of quinine in experimental animals. Arch Otolrrryngol 1959; 70: 321
  • Hugo W. B., Longworth A. R. Some aspects of the mode of action of chlorhexidine. J Pharm Pharmacol 1964; 16: 655
  • Kimura R., Perlman H. B. Arterial obstruction of the labyrinth. Part I. Cochlear changes. Ann Otol Rhinol Laryngol 1958; 67: 5
  • Kohonen A. Effect of some ototoxic drugs upon the pattern and innervation of cochlear sensory cells in the guinea pig. Acta Orolaryngol (Stockh.) 1965; 208, Suppl
  • Kohonen A., Tarkkanen J. Cochlear damage from ototoxic antibiotics. Acta Otolaryngol (Stockh.) 1969; 68: 90
  • Koide Y., Hata A., Hando R. Vulnerability of the organ of Corti in poisoning. Acta Otolaryngol (Stockh.) 1965; 61: 332
  • Küpper K., Stupp H., Orsulakova A., Quante M. Vergleichende Untersuchungen der Ototoxicität verschiedener antibiotischer Substanzen bei lokaler Applikation am Innenohr des Meerschweinchens. Arch Klin Exp Ohren Nasan Kehlkopfheilkd 1970; 196: 169
  • Läkartidningen, Aktuellt om läkemedel Klorhexidin starkt toxiskt för innerörat. Läkartidningen 1975; 72: 1213
  • Lawrence C. A. Antimicrobial activity, in vitro, of chlorhexidine. J Am Pharm Assoc 1960; 49: 731
  • Lawrence M. Effects of interference with terminal blood supply on organ of Corti. Laryngoscope 1966; 76: 1318
  • Morizono T., Johnstone B. M., Hadjar E. The ototoxicity of antiseptics. J Otolaryngol Soc Aust 1973; 3: 550
  • Proud G. O., Mittelman Y., Seiden G. Ototoxicity of topically applied chloramphenicol. Arch Otolaryngol 1968; 87: 580
  • Sadé J. Discussion. Sensorineural Hearing Loss. Ciba Foundation. 1970; 321
  • Schacht J. Interaction of neomycin with phos-phoinositide metabolism in guinea pig inner ear and brain tissues. Ann Otol Rhinol Laryngol 1974; 83: 613
  • Schuknecht H. F. Ablation therapy in the management of Ménière's disease. Acta Otolaryngol (Stockh.) 1957; 132, Suppl
  • Shenoi P. M. Ototoxicity of absorbable gelatin sponge. Proc Roy Soc Med 1973; 66: 193
  • Spoendlin H. Zur Ototoxizitat des Streptomyzins. Pract Otorhinolaryngol 1966; 28: 305
  • Sugiura S., Paparella M. M. The pathology of labyrinthine ossification. Laryngoscope 1967; 77: 1974
  • Wersall J., Björkroth B., Flock Å., Lundquist P. G. Experiments on ototoxic effects of antibiotics. Adv Otorhinolaryngol 1973; 20: 14
  • Weston-Hurst E. Adhesive arachnoiditis and vascular blockage caused by detergents and other chemical irritants: An experimental study. J Pathol Bacteriol 1955; 70: 167
  • Ylikoski J., Wersall J., Björkroth B. Correlative studies on the cochlear pathology and hearing loss in guinea pigs after intoxication with ototoxic antibiotics. Acta Otolaryngol (Stockh.) 1974; 326, Suppl

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