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Acta Oto-Laryngologica Volume 103, 1987 - Issue 1-2
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Original Article

The Function of Migratory Epidermis in the Healing of Tympanic Membrane Perforations in Guinea-pig: A Photographic Study

Alan Johnson Temporal Bone Histopathology Laboratory, Department of Otolaryngology, University of Toronto, Toronto, Canada
&
Michael Hawke Temporal Bone Histopathology Laboratory, Department of Otolaryngology, University of Toronto, Toronto, Canada
Pages 81-86 | Published online: 08 Jul 2009

References

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  • Schuknecht H F. Pathology of the Ear. Harvard University Press, Cambridge, Mass 1974; 218: 226
  • McMinn R MH, Taylor M. The cytology of repair in experimental perforations of the tympanic membrane. Br J Surg 1966; 53(3)222–32
  • McIntire C, Benitez J T. Spontaneous repair of the tympanic membrane. Histopathological studies in the cat. Ann Otol Rhinol Larvngol 1970; 79: 1129–31
  • Reijnen C JH, Kuijpers W. The healing pattern of the drum membrane. Acta Otolaryngol (Stockh) 1971, Suppl 287
  • Clawson J P, Litton W B. The healing process of tympanic membrane perforations. Trans Am Ac Ophthal Otolarvngol 1974; 75: 1302–12
  • Reeve D RE. Repair of large experimental perforations of the tympanic membrane. J Laryngol Otol 1977; 91: 767–78
  • Boedts D. The tympanic epithelium in normal and pathological conditions. Acta Oto-rhino-laryngol Belg 1978; 32: 293–420
  • Stenfors L-E, Carlsöö B, Salén B, Winblad B. Repair of experimental tympanic membrane perforations. Acta Otolaryngol (Stockh) 1980; 90: 332–41
  • Litton W B. Epidermal migration in the ear: the location and characteristics of the generation center revealed by utilizing a radioactive DNA precursor. Acta Otolaryngol (Stockh) 1968, Suppl 240
  • O'Donoghue G M. Epithelial migration on the guinea-pig tympanic membrane: the influence of perforation and ventilating tube insertion. Clin Otolaryngol 1983; 8: 297–303
  • Vizian C B, Matoltsy A G, Mescon H. Epithelialization of small wounds. J Invest Dermatol 1964; 43: 499–507
  • Raknerud N. The ultrastructure of the interfollicular epidermis of the hairless (hr/hr) mouse. J Ultrastruct Res 1975; 52: 32–51
  • Johnson A, Hawke M. An ultrastructural study of the skin of the tympanic membrane and external ear canal of the guinea-pig. J Otolaryngol 1985; 14: 357–64
  • Johnson A, Hawke M, Berger G. Keratin wrinkles, cell ridges and desquamation in the external auditory canal. J Otolaryngol 1984; 13: 345–54
  • Alberti P WMR. Epithelial migration on the tympanic membrane. J Laryngol Otol 1964; 78: 808–30
  • Christiansen C B. Photography in treatment of tympanic membrane perforations. J Laryngol Otol 1984; 98: 107–111

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