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Acta Oto-Laryngologica Volume 131, 2011 - Issue 11
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INNER EAR

The differentiation of mesenchymal stem cells into inner ear hair cell-like cells in vitro

He QinDepartment of Otolaryngology Head and Neck Surgery, Institute of Otolaryngology, General Hospital, Beijing, China; Center of Otolaryngology of PLA, Navy General Hospital, Beijing, China
,
Li-Dong ZhaoDepartment of Otolaryngology Head and Neck Surgery, Institute of Otolaryngology, General Hospital, Beijing, China
,
Jian-He SunDepartment of Otolaryngology Head and Neck Surgery, Institute of Otolaryngology, General Hospital, Beijing, China
,
Li-Li RenDepartment of Otolaryngology Head and Neck Surgery, Institute of Otolaryngology, General Hospital, Beijing, China
,
Wei-Wei GuoDepartment of Otolaryngology Head and Neck Surgery, Institute of Otolaryngology, General Hospital, Beijing, China
,
Hui-Zhan LiuDepartment of Otolaryngology Head and Neck Surgery, Institute of Otolaryngology, General Hospital, Beijing, China
,
Suo-Qiang ZhaiDepartment of Otolaryngology Head and Neck Surgery, Institute of Otolaryngology, General Hospital, Beijing, China
&
Shi-Ming YangDepartment of Otolaryngology Head and Neck Surgery, Institute of Otolaryngology, General Hospital, Beijing, ChinaCorrespondence[email protected] [email protected]
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Pages 1136-1141 | Received 25 Mar 2011, Accepted 16 Jun 2011, Published online: 15 Aug 2011

References

  • Roberson DW, Rubel EW. Cell division in the gerbil cochlea after acoustic trauma. Am J Otol 1994;15:28–34.
  • Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002;418:41–9.
  • Xu W, Zhang X, Qian H, Zhu W, Sun X, Hu J, Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro. Exp Biol Med (Maywood) 2004;229:623–31.
  • Egusa H, Schweizer FE, Wang CC, Matsuka Y, Nishimura I. Neuronal differentiation of bone marrow-derived stromal stem cells involves suppression of discordant phenotypes through gene silencing. J Biol Chem 2005;280:23691–7.
  • Kondo T, Johnson SA, Yoder MC, Romand R, Hashino E. Sonic hedgehog and retinoic acid synergistically promote sensory fate specification from bone marrow-derived pluripotent stem cells. Proc Natl Acad Sci U S A 2005;102:4789–94.
  • Woodbury D, Reynolds K, Black IB. Adult bone marrow stromal stem cells express germline, ectodermal, endodermal, and mesodermal genes prior to neurogenesis. J Neurosci Res 2002;69:908–17.
  • Grove JE, Bruscia E, Krause DS. Plasticity of bone marrow-derived stem cells. Stem Cells 2004;22:487–500.
  • Satoh T, Fekete DM. Clonal analysis of the relationships between mechanosensory cells and the neurons that innervate them in the chicken ear. Development 2005;132:1687–97.
  • Sanchez-Ramos J, Song S, Cardozo-Pelaez F, Hazzi C, Stedeford T, Willing A, Adult bone marrow stromal cells differentiate into neural cells in vitro. Exp Neurol 2000;164:247–56.
  • Kabos P, Ehtesham M, Kabosova A, Black KL, Yu JS. Generation of neural progenitor cells from whole adult bone marrow. Exp Neurol 2002;178:288–93.
  • Doetzlhofer A, White PM, Johnson JE, Segil N, Groves AK. In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme. Dev Biol 2004;272:432–47.
  • Guan K, Chang H, Rolletschek A, Wobus AM. Embryonic stem cell-derived neurogenesis. Retinoic acid induction and lineage selection of neuronal cells. Cell Tissue Res 2001;305:171–6.
  • Qian X, Davis AA, Goderie SK, Temple S. FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells. Neuron 1997;18:81–93.
  • León Y, Vazquez E, Sanz C, Vega JA, Mato JM, Giraldez F, Insulin-like growth factor-I regulates cell proliferation in the developing inner ear, activating glycosyl-phosphatidylinositol hydrolysis and Fos expression. Endocrinology 1995;136:3494–503.
  • Li H, Liu H, Heller S. Pluripotent stem cells from the adult mouse inner ear. Nat Med 2003;9:1293–9.
  • Li H, Roblin G, Liu H, Heller S. Generation of hair cells by stepwise differentiation of embryonic stem cells. Proc Natl Acad Sci U S A 2003;100:13495–500.

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