109
Views
0
CrossRef citations to date
0
Altmetric
ONCOLOGY

Preparation of human scFv antibody against nasopharyngeal carcinoma and identification of its specificity

, , , , , , & show all
Pages 663-670 | Received 21 Nov 2011, Accepted 27 Dec 2011, Published online: 12 Apr 2012

References

  • Cho WC. Nasopharyngeal carcinoma: molecular biomarker discovery and progress. Mol Cancer 2007;6:1.
  • Marks JE, Phillips JL, Menck HR. The National Cancer Date Base report on the relation of race and national origin to the histology of NPC. Cancer 1998;83:582–8.
  • Lee AW, Poon YF, Foo W. Retrospective analysis of 5037 patients with NPC treated during 1976–1985: overall survival and patterns of failure. Int J Radiat Oncol Biol Phys 1992;23:261–70.
  • Sanguineti G, Geara FB, Garden AS, Tucker SL, Ang KK, Morrison WH, Carcinoma of the nasopharynx treated by radiotherapy alone: determinants of local and regional control. Int J Radiat Oncol Biol Phys 1997;37:985–96.
  • Lee AW, Tung SY, Chua DT, Ngan RK, Chappell R, Tung R, Randomized trial of radiotherapy plus concurrent-adjuvant chemotherapy vs radiotherapy alone for regionally advanced nasopharyngeal carcinoma. J Natl Cancer Inst 2010;102:1188–98.
  • Wu AM, Senter PD. Arming antibodies: prospects and challenges for immuno-conjugates. Nat Biotechnol 2005;23:1137–46.
  • Balhorn R, Hok S, Burke PA, Lightstone FC, Cosman M, Zemla A, Selective high-affinity ligand antibody mimics for cancer diagnosis and therapy: initial application to lymphoma leukemia. Clin Cancer Res 2007;13:5621–8.
  • Pfeiffer P, Qvortrup C, Eriksen JG. Current role of antibody therapy in patients with metastatic colorectal cancer. Oncogene 2007;26:3661–78.
  • Fietz T, Thiel E. Antibody therapy in non-Hodgkin's lymphoma: the role of rituximab, 90Y-ibritumomab tiuxetan, and alemtuzumab. Recent Results Cancer Res 2007;176:153–63.
  • Berger M, Shankar V, Vafai A. Therapeutic applications of monoclonal antibodies. Am J Med Sci 2002;324:14–30.
  • Köhler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975;256:495–7.
  • Hudson PJ, Souriau C. Engineered antibodies. Nat Med 2003;9:129–34.
  • McCafferty J, Griffiths AD, Winter G, Chiswell DJ. Phage antibodies: filamentous phage displaying antibody variable domains. Nature 1990;348:552–4.
  • Kim SJ, Park Y, Hong HJ. Antibody engineering for the development of therapeutic antibodies. Mol Cells 2005;20:17–29.
  • Cai X, Garen A. Anti-melanoma antibodies from melanoma patients immunized with genetically modified autologous tumor cells: selection of specific antibodies from single-chain Fv fusion phage libraries. Proc Natl Acad Sci USA 1995;92:6537–41.
  • Allen D, Cumano A, Dildrop R. Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development. Immunol Rev 1987;96:5–22.
  • Dohmen SE, Mulder A, Verhagen QJ, Eijsink C, Frank-vanDijk ME, van der Schoot CE. Production of recombinant Ig molecules from antigen-selected single B cells and restricted usage of Ig-gene segments by anti-D antibodies. J Immunol Methods 2005;298:9–20.
  • Shui X, Huang J, Li YH, Xie PL, Li GC. Construction and selection of human Fab antibody phage display library of liver cancer. Hybridoma 2009;28:341–7.
  • He X, Li G, Zhu J. Construction and selection of human anti-idiotypic antibody single chain variable fragments or CDR3 fragments of nasopharyngeal carcinoma. J Exp Clin Cancer Res 2004;23:607–15.
  • Vaughan TJ, Williams AJ, Pritchard K, Osbourn JK, Pope AR, Earnshaw JC, Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library. Nat Biotechnol 1996;14:309–14.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.