158
Views
12
CrossRef citations to date
0
Altmetric
LARYNX

A high nuclear nm23-H1 expression is associated with a better prognosis in elderly patients with laryngeal carcinoma

, , , , , , , & show all
Pages 874-880 | Received 25 Nov 2012, Accepted 09 Feb 2013, Published online: 14 Jun 2013

References

  • Balducci L, Ershler WB. Cancer and ageing: a nexus at several levels. Nat Rev Cancer 2005;5:655–62.
  • Chu EA, Kim YJ. Laryngeal cancer: diagnosis and preoperative work-up. Otolaryngol Clin North Am 2008;41:673–95.
  • Bosnar MH, De Gunzburg J, Bago R, Brecevic L, Weber I, Pavelic J. Subcellular localization of A and B Nm23/NDPK subunits. Exp Cell Res 2004;298:275–84.
  • Steeg PS, Bevilacqua G, Pozzatti R, Liotta LA, Sobel ME. Altered expression of NM23, a gene associated with low tumor metastatic potential, during adenovirus 2 Ela inhibition of experimental metastasis. Cancer Res 1988;48:6550–4.
  • Tee YT, Chen GD, Lin LY, Ko JL, Wang PH. Nm23–H1: a metastasis-associated gene. Taiwan J Obstet Gynecol 2006;45:107–13.
  • Lee CS, Redshaw A, Boag G. nm23-H1 protein immunoreactivity in laryngeal carcinoma. Cancer 1996;77:2246–50.
  • Gunduz M, Ayhan A, Gullu I, Onerci M, Hosal AS, Gursel B, et al. nm23 protein expression in larynx cancer and the relationship with metastasis. Eur J Cancer 1997;33:2338–41.
  • Sobin LH, Gospodarowicz MK, Wittekind C. editors. TNM classification of malignant tumors. 7th edn. Oxford: Wiley-Blackwell. 2009.
  • Extermann M. Management issues for elderly patients with breast cancer. Curr Treat Options Oncol 2004;5:161–9.
  • Marioni G, Staffieri A, Lora L, Fermo S, Giacomelli L, La Torre FB, et al. mTOR expression and prognosis in elderly patients with laryngeal carcinoma: uni- and multivariate analyses. Oral Oncol 2012;48:530–4.
  • Marioni G, Blandamura S, Lionello M, Giacomelli L, Staffieri C, Fasanaro E, et al. Nuclear MASPIN expression relates to a better prognosis in elderly patients with laryngeal carcinoma. Acta Otolaryngol 2011;131:1220–5.
  • Marioni G, Staffieri A, Manzato E, Ralli G, Lionello M, Giacomelli L, et al. A higher CD105-assessed microvessel density and worse prognosis in elderly patients with laryngeal carcinoma. Arch Otolaryngol Head Neck Surg 2011;137:175–80.
  • Mhawech-Fauceglia P, Dulguerov P, Beck A, Bonet M, Allal AS. Value of ezrin, maspin and nm23-H1 protein expressions in predicting outcome of patients with head and neck squamous-cell carcinoma treated with radical radiotherapy. J Clin Pathol 2007;60:185–9.
  • Li X, Hu R, Qu J, He Q, Chen Y, Li J, et al. Identification of nm23-H1 as a metastatic suppressor and prognostic factor in nasopharyngeal carcinoma by proteomic analysis. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2012;37:17–26.
  • Ismail N, Kaur G, Hashim H. Nuclear localization and intensity of staining of nm23 protein is useful marker for breast cancer progression. Cancer Cell Int 2008;8:6.
  • Bosnar MH, Bago R, Cetković H. Subcellular localization of Nm23/NDPK A and B isoforms: a reflection of their biological function? Mol Cell Biochem 2009;329:63–71.
  • Kaetzel DM, Zhang Q, Yang M, McCorkle JR, Ma D, Craven RJ. Potential roles of 3'-5' exonuclease activity of NM23-H1 in DNA repair and malignant progression. J Bioenerg Biomembr 2006;38:163–7.
  • Karanjawala ZE, Lieber MR. DNA damage and aging. Mech Ageing Dev 2004;125:405–16.
  • Kim SH, Lee SY, Park HR, Sung JM, Park AR, Kang S, et al. Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance. Cancer 2011;117:1864–73.
  • Marshall JC, Collins J, Marino N, Steeg P. The Nm23-H1 metastasis suppressor as a translational target. Eur J Cancer 2010;46:1278–82.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.