References
- Henkin RI, Bradley DF. Hypogeusia corrected by Ni++ and Zn++. Life Sci 1970;9:701–9.
- Burch RE, Sackin DA, Ursick JA, Jetton MM, Sullivan JF. Decreased taste and smell acuity in cirrhosis. Arch Intern Med 1978;138:743–6.
- Hambidge KM, Hambidge C, Jacobs M, Baum JD. Low levels of zinc in hair,anorexia, poor growth, and hypogeusia in children. Pediatr Res 1972;6:868–74.
- Ikeda M, Ikui A, Komiyama A, Kobayashi D, Tanaka M. Causative factors of taste disorders and therapeutic effects of zinc agents among aged people. J Laryngol Otol 2008;122:155–60.
- Sakagami M, Ikeda M, Tomita H, Ikui A, Aiba T, Takeda N, et al. A zinc containing compound, polaprezinc, is effective for patients with taste disorders: randomized, double-blind, placebo-controlled, multi-center study. Acta Otolaryngol 2009;129:1115–20.
- Komai M, Goto T, Suzuki H, Takeda T, Furukawa Y. Zinc deficiency and taste dysfunction; contribution of carbonic anhydrase, a zinc-metalloenzyme, to normal taste sensation. BioFactors 2000;12:65–70.
- Hamano H, Yoshinaga K, Eta R, Emori Y, Kawasaki D, Iino Y, et al. Effect of polaprezinc on taste disorders in zinc-deficient rats. Biofactors 2006;28:185–93.
- Lindemann B. Receptors and transduction in taste. Nature 2001;413:219–25.
- Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS. The receptors and cells for mammalian taste. Nature 2006;444:288–94.
- Hoon MA, Adler E, Lindemeier J, Battey JF, Ryba NJ, Zuker CS. Putative mammalian taste recepters: a class of taste-specific GPCRs with distinct topographic selectivity. Cell 1999;96:541–51.
- Chandrashekar J, Mueller KL, Hoon MA, Adler E, Feng L, Guo W, et al. T2Rs function as bitter taste receptors. Cell 2000;100:703–11.
- Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, Bufe B, et al. The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 2010;35:157–70.
- Lin W, Finger TE, Rossier BC, Kinnamon SC. Epithelial Na+ channel subunits in rat taste cells: localization and regulation by aldosterone. J Comp Neurol 1999;405:406–20.
- Chandrashekar J, Kuhn C, Oka Y, Yarmolinsky DA, Hummler E, Ryba NJ, et al. The cells and peripheral representation of sodium taste in mice. Nature 2010;464:297–301.
- Onoda K, Hirai R, Takao K, Kokubun S, Ikeda M. Patients with hypogeusia show changes in expression of T2R taste receptor genes in their tongues. Laryngoscope 2011;121:2592–7.
- Hirai R, Takao K, Onoda K, Kokubun S, Ikeda M. Patients with phantogeusia show increased expression of T2R taste receptor genes in their tongues. Ann Otol Rhinol Laryngol 2012;121:113–18.
- Sekine H, Takao K, Yoshinaga K, Kokubun S, Ikeda M. Effects of zinc deficiency and supplementation on gene expression of bitter taste receptors (TAS2Rs) on the tongue in rats. Laryngoscope 2012;122:2411–17.
- Miura H, Kusakabe Y, Sugiyama C, Kawamatsu M, Ninomiya Y, Motoyama J, et al. Shh and Ptc are associated with taste bud maintenance in the adult mouse. Mech Dev 2001;106:143–5.
- Goodrich LV, Johnson RL, Milenkovic L, McMahon JA, Scott MP. Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev 1996;10:301–12.
- Miura H, Kato H, Kusakabe Y, Tagami M, Miura-Ohnuma J, Ookura T, et al. Shh signaling and regulatory gene expression in the mouse taste buds. Chem Senses 2005;30(Suppl):i50–1.