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MIDDLE EAR

The oncoprotein, gankyrin, is up-regulated in middle ear cholesteatoma

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Pages 238-243 | Received 05 Jul 2013, Accepted 01 Sep 2013, Published online: 27 Jan 2014

References

  • Mallet Y, Nouwen J, Lecomte-Houcke M, Desaulty A. Aggressiveness and quantification of epithelial proliferation of middle ear cholesteatoma by MIB1. Laryngoscope 2003;113:328–31.
  • Park K, Moon SK, Choung YH, Choi HS. Expression of beta-defensins in human middle ear cholesteatoma. Acta Otolaryngol 2003;123:236–40.
  • Byun JY, Yune TY, Lee JY, Yeo SG, Park MS. Expression of CYLD and NF-κB in human cholesteatoma epithelium. Mediators Inflamm 2010;2010:1–6.
  • Wakamori M, Umehara T, Yokoyama S. A series of bacterial co-expression vectors with rare-cutter recognition sequences. Protein Exp Purif 2010;74:88–98.
  • Higashitsuji H, Higashitsuji H, Itoh K, Sakurai T, Nagao T, Sumitomo Y, et al. The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53. Cancer Cell 2005;8:75–87.
  • Huisman MA, De Heer E, Grote JJ. Cholesteatoma epithelium is characterized by increased expression of Ki-67, p53 and p21, with minimal apoptosis. Acta Otolaryngol 2003;123:377–82.
  • Motamed M, Powe D, Kendall C, Birchall JP, Banerjee AR. p53 Expression and keratinocyte hyperproliferation in middle ear cholesteatoma. Clin Otolaryngol Allied Sci 2002;27:505–8.
  • Raynov AM, Moon SK, Choung YH, Hong SP, Park K. Nucleoplasm staining patterns and cell cycle-associated expression of Ki-67 in middle ear cholesteatoma. Am J Otolaryngol 2005;26:296–301.
  • Sudhoff H, Dazert S, Gonzales AM, Borkowski G, Park SY, Baird A, et al. Angiogenesis and angiogenic growth factors in middle ear cholesteatoma. Am J Otol 2000;21:793–8.
  • Vitale RF, Pereira CSB, Alves AL, Fregnani JHTG, Ribeiro FQ. TNF-R2 expression in acquired middle ear cholesteatoma. Braz J Otorhinolaryngol 2011;77:531–6.
  • Jung MH, Lee JH, Cho JG, Jung HH, Hwang SJ, Chae SW. Expressions of caspase-14 in human middle ear cholesteatoma. Laryngoscope 2009;118:1047–50.
  • Choung YH, Park K, Kang SO, Markov Raynov A, Ho Kim C, Choung PH. Expression of the gap junction proteins connexin 26 and connexin 43 in human middle ear cholesteatoma. Acta Otolaryngol 2006;126:138–43.
  • Li J, Knobloch TJ, Kresty LA, Zhang Z, Lang JC, Schuller DE, et al. Gankyrin, a biomarker for epithelial carcinogenesis, is overexpressed in human oral cancer. Anticancer Res 2011;31:2683–92.
  • Kojima H, Tanaka Y, Tanaka T, Miyazaki H, Shiwa M, Kamide Y, et al. Cell proliferation and apoptosis in human middle ear cholesteatoma. Arch Otolaryngol Head Neck Surg 1998;124:261–4.
  • Iakova P, Timchenko L, Timchenko NA. Intracellular signaling and hepatocellular carcinoma. Semin Cancer Biol 2011;21:28–34.
  • Allred DC, Clark GM, Elledge R, Fuqua SA, Brown RW, Chamness GC, et al. Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J Natl Cancer Inst 1993;85:200–6.
  • Macip S, Igarashi M, Berggren P, Yu J, Lee SW, Aaronson SA. Influence of induced reactive oxygen species in p53-mediated cell fate decisions. Mol Cell Biol 2003;23:8576–85.
  • Ganguli G, Abecassis J, Wasylyk B. MDM2 induces hyperplasia and premalignant lesions when expressed in the basal layer of the epidermis. EMBO J 2000;19:5135–47.

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