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Acta Oto-Laryngologica Volume 110, 1990 - Issue 1-2
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Original Article

An Alternative Treatment for the Reduction of Tympanic Membrane Perforations: Sodium Hyaluronate: A Double Blind Study

M. P. Rivas Lacarte Departments of Oto-Rhino-Laryngology, Viladecans Hospital, Barcelona, Spain
,
T. Casasin Departments of Pharmacy, Viladecans Hospital, Barcelona, Spain
,
F. Pumarola Departments of Oto-Rhino-Laryngology, Viladecans Hospital, Barcelona, Spain
&
A. Alonso Departments of Statistics, Viladecans Hospital, Barcelona, Spain
Pages 110-114 | Received 11 Jul 1989, Accepted 12 Dec 1989, Published online: 08 Jul 2009

References

  • Stenfors L E, Berghem L, Bloom G D, Hellström S, Söderberg O. Exogenous hyaluronic acid (Healon) accelerates the healing of experimental myringotomies. Auris-Nasus-Larynx (Tokyo) 1985; Suppl. 1: 217–8
  • Stenfors L E. Repair of tympanic membrane perforations using hyaluronic acid: An alternative to myringoplasty. J Laryngol Otol 1989; 103: 39–40
  • Stenfors L E. Treatment of tympanic membrane perforations with hyaluronan in an open pilot study of unselected patients. Acta Otolaryngol (Stockh) 1987; Suppl. 442: 81–7
  • Stenfors L E. Repair of traumatically ruptured tympanic membrane using hyaluronan. Acta Otolaryngol (Stockh) 1987; Suppl. 442: 88–91
  • Rivas M P, Casasin T, Pumarola F, Alonso A. Tratamiento de las perforaciones timpanicas con hialuronato sódico I. Relatión con la etiología de la perforateón. II. Audiometría antes y después del tratamiento. O.R.L.–DIPS Internacional (Barcelona) 1989; 5: 229–34
  • Clawson J P, Litton W B. The healing process of tympanic membrane perforations. Trans Am Acad Ophthalmol Otolaryngol 1971; 75: 1302–12
  • Bothner H, Wik H. Rheology of hyaluronate. Acta Otolaryngol (Stockh) 1987; Suppl. 442: 25–30
  • Gibbs D A, Merill E W, Smith K A, Balazs E A. Rheology of hyaluronic acid. Biopolymers 1968; 6: 777–91
  • Hakansson L, Hallagren R, Venge P. Regulation of granulocyte function by hyaluronic acid. In vitro and in vivo effects on phagocytosis, locomotion and metabolism. J Clin Invest 1980; 66: 298–305
  • Hellstrom S, Laurent C. Hyaluronan and healing of tympanic membrane perforations. An experimental study. Acta Otolaryngol (Stockh) 1987; Suppl. 442: 54–61
  • Morris E R, Ress D A, Welsh E J. Conformation and dynamic interactions in hyaluronate solutions. J Mol Biol 1980; 138: 383–400
  • Reeve D RE. Repair of large experimental perforations of the tympanic membrane. J Laryngol Otol 1977; 91: 767–78

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