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Original Article

Epidermal Growth Factor Receptor, c-erbB-2 and p53 Overexpressions in Epithelial Hyperplastic Lesions of the Larynx

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Pages 105-110 | Published online: 08 Jul 2009

References

  • Kambič V, Gale N. Epithelial hyperplastic lesions of the larynx. Elsevier, Amsterdam 1995; 1–265
  • Uhlman D L, Adams G, Knapp D, Aeppli D M, Nie-Hans G. Immunohistochemical staining for markers of future neoplastic progression in the larynx. Cancer Res 1996; 56: 2199–205
  • Rusch V, Klimstra D, Linkov I, Dmitrovsky E. Aberrant expression of p53 or the epidermal growth factor receptor is frequent in early bronchial neoplasia, and coexpression precedes squamous cell carcinoma development. Cancer Res 1995; 55: 1365–72
  • Shin D M, Ro J Y, Hong W K, Hittelman W N. Dys-regulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis. Cancer Res 1994; 54: 3153–9
  • Wagner U, Sauter G, Moch H, et al. Patterns of p53, erbB-2, and EGF-r expression in premalignant lesions of the urinary bladder. Hum Pathol 1995; 26: 970–8
  • Kearsley J H, Leonard J H, Walsh M D, Wright G R. A comparison of epidermal growth factor receptor (EGFR) and c-erbB-2 oncogene expression in head and neck squamous cell carcinomas. Pathology 1991; 23: 189–94
  • Miyaguchi M, Olofsson J, Hellquist H B. Expression of epidermal growth factor receptor in laryngeal dysplasia and carcinoma. Acta Otolaryngol (Stockh) 1990; 110: 309–13
  • Underwood M, Bartlett J, Reeves J, Gdrdiner D S, Scott R, Cooke T. c-erbB-2 gene amplification: a molecular marker in recurrent bladder tumors?. Cancer Res 1995; 55: 2422–30
  • Bacus S, Zelnick C R, Plowman G, Yarden Y. Expression of the erbB-2 family of growth factor receptors and their ligands in breast cancers. Am J Clin Pathol 1994; 102((Suppl 1))S13–24
  • Gorgoulis V G, Barbatis C, Poulias I, Karameris A M. Molecular and immunohistochemical evaluation of epidermal growth factor receptor and c-erb-B-2 gene product in transitional cell carcinomas of the urinary bladder: a study in Greek patients. Mod Pathol 1995; 8: 758–64
  • Craven J M, Pavelic Z P, Stambrook P J, et al. Expression of c-erbB-2 gene in human head and neck carcinoma. Anticancer Res 1992; 12: 2273–6
  • Field J K, Spandidos D A, Yiagnisis M, Gosney J R, Papadimitriou K, Stell P M. c-erbB-2 Expression in squamous cell carcinoma of the head and neck. Anticancer Res 1992; 12: 613–20
  • Bron J, Monnier P. Molecular alterations in head and neck squamous cell carcinoma. Clin Otolaryngol 1995; 20: 291–8
  • Dolcetti R, Doglioni C, Maestro R, et al. p53 over-expression is an early event in the development of human squamous-cell carcinoma of the larynx: genetic and prognostic implications. Int J Cancer 1992; 52: 178–82
  • Shin D M, Kim J, Ro J Y, et al. Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis. Cancer Res 1994; 54: 321–6
  • Munck-Wikland E, Edstrom S, Jungmark E, Kuylenstierna R, Lindholm J, Auer G. Nuclear DNA content, proliferating-cell nuclear antigen (PCNA) and p53 immunostaining in predicting progression of laryngeal cancer in situ lesions. Int J Cancer 1994; 56: 95–9
  • Pavelic Z P, Li Y Q, Stambrook P J, et al. Overexpres-sion of p53 protein is common in premalignant head and neck lesions. Anticancer Res 1994; 14: 2259–66
  • Kambič V, Gale N, Ferluga D. Laryngeal hyperplastic lesions, follow-up study and application of lectins and anticytokeratins for their evaluation. Pathol Res Pract 1992; 188: 1067–77
  • Lavieille J P, Brainbilla E, Riva-Lavieille C, Reyt E, Charachon R, Brambilla C. Immunohistochemica∼ detection of p53 protein in preneoplastic lesions and squainous cell carcinoma of the head and neck. Actd Otolaryngol (Stockh) 1995; 115: 334–9
  • Poljak M, Gale N., Kambič V, Ferluga D, Fischinger J. Overexpression of p53 protein in benign and malignant laryngeal epithelial lesions. Anticancer Res 1996; 16: 1947–52

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