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Research Article

Treatment Of Acute Methylmercury Ingestion By Hemodialysis With N-Acetylcysteine (Mucomyst) Infusion And 2,3-Dimercaptopropane Sulfonate

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Pages 31-49 | Published online: 25 Sep 2008

References

  • Bakir F., Damluji S. F., Amin-Zaki L. Methyl mercury poisoning in Iraq. an interuniversity report, Science 1973; 181: 230–240
  • Harada M., Smith A. M. Minimata disease. A medical report, WE Smith Minimata, AM Smith. Holt, Rinehart and Winston, New York 1975; 180–192
  • Clarkson T. W., Magos K., Cox C. Tests of efficacy of antidotes for removal of methyl mercury in human poisoning during the Iraq outbreak. J Pharmacol Exp Ther 1981; 218: 74–83
  • WHO Task Group on Envrionmental Health. Environmental Health Criteria 1 - Mercury. WHO, Geneva 1976
  • Magos L., Clarkson T. W. Atomic absorption determination of total, inorganic, and organic mercury in blood. J Assoc Of Anal Chem 1972; 55: 966–971
  • Giovanoli-Jakubczak T., Greenwood M. R. Determination of total inorganic mercury in hair by flameless atomic absorption, and of methyl mercury by gas chromatography. Clin Chem 1974; 20: 222–229
  • Kershaw T. G., Dhahir P. H., Clarkson T. W. The relationship between blood levels and dose of methylmercury in man. Arch Environ Health 1980; 35: 28–36
  • Miettinen J. K. Absorption and elimination of dietary mercury (Hg2+) and methylmercury in man. Mercury, mercurials, and mercaptans, MW Miller, TW Clarkson. CC Thomas, Springfield, Illinois 1973; 233–243
  • Clarkson T. W. The pharmacology of mercury compounds. Ann Rev Pharmacol 1972; 12: 375–406
  • Magos L., Peristianis G. C., Snowden R. T. Postexposure preventive treatment of methylmercury intoxication in rats with dimercaptosuccinic acid. Toxicol Appl Pharmacol 1978; 45: 463–475
  • Zimmer L., Carter D. E. Effects of complexing treatment of administered with the onset of methylmercury neurotoxic signs. Toxicol Appl Pharmacol 1979; 51: 29–38
  • Elhassani S. B. The Many Faces of Methylmercury Poisoning. J Toxicol:CI in Toxicol 1982–1983; 19: 875–906
  • Norseth T., Clarkson T. W. Intestinal transport of 203Hg-labelled methylmercury chloride: Role of biotransformation in rats. Arch Environ Health 1971; 22: 568–577
  • Ishiara N., Shiojimas S., Suzuki T. Selective enhancement of urinary oraanic mercury excretion by D-penicillamine. Br J Indeed 1974; 31: 245–249
  • Clarkson T. W., Small H., Norseth T. Excretion and absorption of methylmercury after polythiol resin treatment. Arch Environ Health 1973; 26: 173–176
  • Margel S. 1981. A novel approach for heavy metal poisoning treatment, a model. Mercury poisoning by means of chelatinq microspheres: Hemoperfusion and oral administration. J Med Chem 1981; 24: 1263–1266
  • Kostyniak P. J., Clarkson T. W., Cestero R. V. An extracorporeal complexing hemodialysis system for the treatment of methylmercury poisoning. I. In vitro studies of the effects of four complexing agents on the distribution and dialyzability of methyl mercury in human blood. J Pharmacol Exp Ther 1975; 192: 260–269
  • Kostyniak P. J., Clarkson T. W., Al-Abbasi A. H. An extracorporeal complexing hemodialysis system for the treatment of methylmercury poisoning. II. In vivo applications in the dog. J Pharmacol Exp Ther 1977; 203: 253–263
  • Al-Abbasi A. H., Kostyniak P. J., Clarkson T. W. An extracorporeal complexing hemodialysis system for the treatment of methylmercury poisoning. III. Clinical applications. J Pharmacol Exp Ther 1978; 207: 249–254
  • Aaseth J., Friedheim E. A.H. Treatment of methylmercury poisoning in mice with 2,3-dimercaptosuccinic acid and other complexing thiols. Acta Pharmacol et Toxicol 1973; 42: 248–252
  • Gabard B. Treatment of methylmercury poisoning in the rat with sodium 2,3-dimercaptopropaent-sulfonate: influence of dose and mode of administration. Toxicol Appl Pharmacol 1976; 38: 415–424
  • Gabard B., Walser R. Note on the metabolism of the mercury chelating agent sodium 2,3-dimercaptopropane-1-sulfonate. J Toxicol Environ Health 1979; 5: 759–764
  • Aposhian H. V. DMSA and DMPS–water soluble antidotes for heavy metal poisoning. Ann Rev Pharmacol Toxicol 1983; 23: 193–215

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