The Impact of Allodynia on the Efficacy of Almotriptan When Given Early in Migraine: Data From the “Act When Mild” Study

REFERENCES

• Bigal, M. E., Ashina, S., Burstein, R., Reed, M. L., Buse, D., Serrano, D., (2008). Prevalence and characteristics of allodynia in headache sufferers: A population study. Neurology, 70, 1525–1533.
   PubMed Web of Science ®Google Scholar
• Burstein, R., Collins, B., & Jakubowski, M. (2004). Defeating migraine pain with triptans: A race against the development of cutaneous allodynia. Annals of Neurology, 55, 19–26.
   PubMed Web of Science ®Google Scholar
• Burstein, R., Cutrer, M. F., & Yarnitsky, D. (2000). The development of cutaneous allodynia during a migraine attack: Clinical evidence for the sequential recruitment of spinal and supraspinal nociceptive neurons in migraine. Brain, 123(Pt 8), 1703– 1709.
   PubMed Web of Science ®Google Scholar
• Burstein, R., Yamamura, H., Malick, A., & Strassman, A. M. (1998). Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons. Journal of Neurophysiology, 79, 964–982.
   PubMed Web of Science ®Google Scholar
• Burstein, R., Yarnitsky, D., Goor-Aryeh, I., Ransil, B. J., & Bajwa, Z. H. (2000). An association between migraine and cutaneous allodynia. Annals of Neurology, 47, 614–624.
   PubMed Web of Science ®Google Scholar
• Díaz-Insa, S., Goadsby, P. J., Zanchin, G., de Klippel, N., Geraud, G., Cunha, L., (2009). Early treatment with almotriptan allows a good outcome even in allodynic migraine patients: An Act when Mild (AwM) substudy. Cephalalgia, 29:101–78. PC.02.
   Google Scholar
• Dowson, A. J., Massiou, H., Lainez, J. M., & Cabarrocas, X. (2004). Almotriptan improves response rates when treatment is within 1 hour of migraine onset. Headache, 44, 318–322.
   PubMed Web of Science ®Google Scholar
• Freitag, F. G., Finlayson, G., Rapoport, A. M., Elkind, A. H., Diamond, M. L., Unger, J. R., (2007). Effect of pain intensity and time to administration on responsiveness to almotriptan: Results from AXERT 12.5 mg Time Versus Intensity Migraine Study (AIMS). Headache, 47, 519–530.
   PubMed Web of Science ®Google Scholar
• Freitag, F., Smith, T., Mathew, N., Rupnow, M., Greenberg, S., Mao, L., (2008). Effect of early intervention with almotriptan vs placebo on migraine-associated functional disability: Results from the AEGIS Trial. Headache, 48, 341–354.
   PubMed Web of Science ®Google Scholar
• Goadsby, P. J., Charbit, A. R., Andreou, A. P., Akerman, S., & Holland, P. R. (2009). Neurobiology of migraine. Neuroscience, 161, 327–341.
   PubMed Web of Science ®Google Scholar
• Goadsby, P. J., Lipton, R. B., & Ferrari, M. D. (2002). Migraine-current understanding and treatment. New England Journal of Medicine, 346, 257–270.
   PubMed Web of Science ®Google Scholar
• Goadsby, P. J., Zanchin, G., Geraud, G., de Klippel, N., Diaz-Insa, S., Gobel, H., (2008). Early vs. non-early intervention in acute migraine-'Act when Mild (AwM)’. A double-blind, placebo-controlled trial of almotriptan. Cephalalgia, 28, 383–391.
   PubMed Web of Science ®Google Scholar
• Graham, J. R., & Wolff, H. G. (1938). Mechanism of migraine headache and action of ergotamine tartrate. Archives of Neurology and Psychiatry, 39, 737–763.
   Google Scholar
• Jakubowski, M., Silberstein, S., Ashkenazi, A., & Burstein, R. (2005). Can allodynic migraine patients be identified interictally using a questionnaire? Neurology, 65, 1419–1422.
   PubMed Web of Science ®Google Scholar
• Láinez, M. J. (2007). Almotriptan: Meeting today's needs in acute migraine treatment. Expert Review of Neurotherapeutics, 7, 1659–1673.
   PubMedGoogle Scholar
• Láinez, M. J., Pascual, J., Mateos, V., & Galvan, J. (2004). Real world experience comparing neurologists and primary care physician management of acute migraine with almotriptan in Spain. Paper presented at the 56 th Annual Meeting of the American Academy of Neurology, San Francisco, CA.
   Google Scholar
• Landy, S. H., McGinnis, J. E., & McDonald, S. A. (2007). Clarification of developing and established clinical allodynia and pain-free outcomes. Headache, 47, 247–252.
   PubMed Web of Science ®Google Scholar
• Lantéri-Minet, M., Allaf, B., & Mick, G. (2006). Right triptan use in clinical conditions: Results of TEMPO study. Neurology, 66(Supplement 2), A43.
   Google Scholar
• LoPinto, C., Young, W. B., & Ashkenazi, A. (2006). Comparison of dynamic (brush) and static (pressure) mechanical allodynia in migraine. Cephalalgia, 26, 852–856.
   PubMed Web of Science ®Google Scholar
• Mathew, N. T. (2003). Early intervention with almotriptan improves sustained pain-free response in acute migraine. Headache, 43, 1075–1079.
   PubMed Web of Science ®Google Scholar
• Mathew, N. T., Finlayson, G., Smith, T. R., Cady, R. K., Adelman, J., Wright, P., (2007). Early intervention with almotriptan: Results of the AEGIS trial (AXERT® Early Migraine Intervention Study). Headache, 47, 189–198.
   PubMed Web of Science ®Google Scholar
• Mathew, N. T., Kailasam, J., & Seifert, T. (2004). Clinical recognition of allodynia in migraine. Neurology, 63, 848–852.
   PubMed Web of Science ®Google Scholar
• Moskowitz, M. A., Bolay, H., & Dalkara, T. (2004). Deciphering migraine mechanisms: Clues from familial hemiplegic migraine genotypes. Annals of Neurology, 55, 276–280.
   Google Scholar
• Moskowitz, M. A., Henrikson, B. M., Markowitz, S., & Saito, K. (1988). Intra- and extracraniovascular nociceptive mechanisms and the pathogenesis of pain. In J. Olesen and L. Edvinsson (eds.), Basic Mechanisms of Headache. Amsterdam: Elsevier, 429–437.
   Google Scholar
• Pascual, J., & Cabarrocas, X. (2002). Within-patient early versus delayed treatment of migraine attacks with almotriptan: The sooner the better. Headache, 42, 28–31.
   PubMed Web of Science ®Google Scholar
• Pascual, J., Láinez, J. M., Leira, R., Titus, F., Mateos, V., Galván, J., (2003). 2000. [Almotriptan in the treatment of migraine attacks in clinical practice: Results of the TEA 2000 observational study]. Neurologia, 18, 7–17.
   PubMed Web of Science ®Google Scholar
• Pascual, J., Tranche, S., Leira, R., Lainez, J. M., Mateos, V., & Galvan, J. (2003). Almotriptan in clinical practice: Experience in a primary care vs neurology setting [abstract]. Headache, 43, 525.
   Google Scholar
• Schoenen, J., De Klippel, N., Giurgea, S., Herroelen, L., Jacquy, J., Louis, P., (2008). Almotriptan and its combination with aceclofenac for migraine attacks: A study of efficacy and the influence of auto-evaluated brush allodynia. Cephalalgia, 28, 1095–1105.
   PubMed Web of Science ®Google Scholar
• Selby, G., & Lance, J. W. (1960). Observations on 500 cases of migraine and allied vascular headache. Journal of Neurology, Neurosurgery, and Psychiatry, 23, 23–32.
   PubMed Web of Science ®Google Scholar
• Strassman, A. M., Raymond, S. A., & Burstein, R. (1996). Sensitization of meningeal sensory neurons and the origin of headaches. Nature, 384, 560–564.
   PubMed Web of Science ®Google Scholar